GlpBio

Secretin (rat) (trifluoroacetate salt)

目录号: GC48327纯度: >95.00%
A neuropeptide hormone
Secretin (rat) (trifluoroacetate salt)
规格价格库存数量操作
1mg¥3,727.00现货
1
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产品描述 Description

Secretin is a neuropeptide hormone that regulates secretion from the stomach, pancreas, and liver.1,2 It binds to the rat secretin receptor (SCT-R; Ki = 3.3 nM) and increases intracellular cAMP (EC50 = 1 nM) in COS cells expressing rat SCT-R.3 It also increases SCT-R phosphorylation 7.2-fold at a concentration of 0.1 μM. Secretin dose-dependently increases the volume of pancreatic secretion and inhibits gastric acid secretion induced by gastrin I in rats when administered at a dose of 100 pmol/kg per hour.4

1.Kopin, A.S., Wheeler, M.B., and Leiter, A.B.Secretin: Structure of the precursor and tissue distribution of the mRNAProc. Natl. Acad. Sci. U.S.A.87(6)2299-2303(1990) 2.Sekar, R., and Chow, B.K.Metabolic effects of secretinGen. Comp. Endocrinol.18118-24(2013) 3.Ozcelebi, F., Holtmann, M.H., Rentsch, R.U., et al.Agonist-stimulated phosphorylation of the carboxyl-terminal tail of the secretin receptorMol. Pharmacol.48(5)818-824(1995) 4.Solomon, T.E., Keire, D.A., Gong, P., et al.Receptor subtypes: Species variations in secretin affect potency for pancreatic but not gastric secretionPancreas26(3)300-305(2003)

产品文档 Product Documents

Purity:>95.00%Appearance:A solid

化学性质Chemical Properties

SMILES
NC([C@H](C(C)C)NC([C@H](CC(C)C)NC(CNC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CO)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CCC(O)=O)NC([C@H](CO)NC([C@@]([C@@H](C)O)([H])NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC(CNC([C@@H](NC([C@H](CO)NC([C@@H](N[H])CC1=CN=CN1)=O)=O)CC(O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC(O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
分子式
C129H216N42O42•XCF3COOH
分子量
3027.4 g/mol
溶解性
Water: 1 mg/ml
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol