Autophagy
Autophagy(自噬)
Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.
Autophagy 相关产品(1140)
- GC15684KB-R7943 mesylateCAS: 182004-65-5纯度: >98.50%
An inhibitor of the reverse Na + /Ca 2+ exchanger
- GC15706Aspirin (Acetylsalicylic acid)CAS: 50-78-2纯度: >99.50%
A non-selective, irreversible COX inhibitor
- GC15736Rosuvastatin CalciumCAS: 147098-20-2纯度: >99.50%
Rosuvastatin Calcium是一种竞争性HMG-CoA还原酶抑制剂，IC 50 值为11nM。
- GC15794Valproic acid sodium salt (Sodium valproate)CAS: 1069-66-5纯度: >98.00%
Valproic acid sodium salt (Sodium valproate)（VPA）是一种具有口服活性的组蛋白脱乙酰酶 （HDAC）抑制剂，IC 50 值为1.5mM，抑制HDAC1的IC 50 值为400μM，同时可诱导HDAC2的降解。
- GC15814Pamapimod (R-1503, Ro4402257)CAS: 449811-01-2纯度: >99.50%
An orally bioavailable inhibitor of p38α MAP kinase
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC15668 | Meprednisone | 1247-42-3 | >99.50% | |
A corticosteroid | ||||
| GC15680 | Perifosine | 157716-52-4 | >98.00% | |
Perifosine 是 Akt 的抑制剂 。 | ||||
| GC15684 | KB-R7943 mesylate | 182004-65-5 | >98.50% | |
An inhibitor of the reverse Na + /Ca 2+ exchanger | ||||
| GC15706 | Aspirin (Acetylsalicylic acid) | 50-78-2 | >99.50% | |
A non-selective, irreversible COX inhibitor | ||||
| GC15725 | PTC-209 | 315704-66-6 | >98.00% | |
PTC-209 是一种小分子化合物，可选择性抑制 BMI-1，在 HT1080 细胞中的 IC50 为 0.5μM，是一种很有前途的抗癌药物在体外，PTC-209 以 0.1 到 10μM 之间的剂量处理人结直肠癌细胞，以剂量依赖性方式降低 BMI-1 蛋白水平，同时减少细胞生长。 | ||||
| GC15730 | Kaempferide | 491-54-3 | >98.00% | |
A flavonoid with diverse biological activities | ||||
| GC15736 | Rosuvastatin Calcium | 147098-20-2 | >99.50% | |
Rosuvastatin Calcium是一种竞争性HMG-CoA还原酶抑制剂，IC 50 值为11nM。 | ||||
| GC15741 | LY2603618 | 911222-45-2 | >98.00% | |
A Chk1 inhibitor | ||||
| GC15742 | OSU-03012 (AR-12) | 742112-33-0 | - | |
An anti-cancer celecoxib analog | ||||
| GC15785 | Saquinavir mesylate | 149845-06-7 | >98.50% | |
An HIV protease inhibitor | ||||
| GC15794 | Valproic acid sodium salt (Sodium valproate) | 1069-66-5 | >98.00% | |
Valproic acid sodium salt (Sodium valproate)（VPA）是一种具有口服活性的组蛋白脱乙酰酶 （HDAC）抑制剂，IC 50 值为1.5mM，抑制HDAC1的IC 50 值为400μM，同时可诱导HDAC2的降解。 | ||||
| GC15810 | Clinofibrate | 30299-08-2 | >99.50% | |
A hypolipidemic agent | ||||
| GC15814 | Pamapimod (R-1503, Ro4402257) | 449811-01-2 | >99.50% | |
An orally bioavailable inhibitor of p38α MAP kinase | ||||
| GC15818 | RAF265 | 927880-90-8 | >99.50% | |
A B-Raf and VEGFR2 inhibitor | ||||
| GC15826 | Isosorbide | 652-67-5 | >98.00% | |
A dianhydrohexitol | ||||
| GC15854 | Mefloquine hydrochloride | 51773-92-3 | >99.50% | |
An antimalarial compound | ||||
| GC15857 | Sodium butyrate | 156-54-7 | >99.00% | |
A short-chain fatty acid and HDAC inhibitor | ||||
| GC15864 | CCT128930 | 885499-61-6 | >99.50% | |
An inhibitor of Akt2 | ||||
| GC15875 | ABT-751 (E7010) | 141430-65-1 | >99.50% | |
An inhibitor of microtubule polymerization | ||||
| GC15890 | Cilostazol | 73963-72-1 | >99.50% | |
A PDE3A inhibitor | ||||
| GC15904 | PP242 | 1092351-67-1 | >98.50% | |
Potent inhibitor of mTOR kinase in both mTORC1 and mTORC2 | ||||
| GC15924 | L-779,450 | 303727-31-3 | >98.50% | |
A B-Raf inhibitor | ||||
| GC15929 | Levosimendan | 141505-33-1 | >99.50% | |
A calcium sensitizer | ||||
| GC15951 | URB597 | 546141-08-6 | >99.00% | |
An inhibitor of FAAH | ||||