GlpBio

Src

Src(Src激酶)

Src (proto-oncogene tyrosine-protein kinase) is a non-receptor protein tyrosine kinase family including 9 members and promotes survival, angiogenesis, proliferation and invasion pathways.

Src 相关产品(101)

  • GC34109 structure
    GC34109Tirbanibulin Mesylate (KX2-391 (Mesylate))
    CAS: 1080645-95-9
    纯度: >99.50%

    A Src kinase inhibitor

  • GC34110 structure
    GC34110WEHI-345 analog
    CAS: 1354825-62-9
    纯度: >99.00%

    WEHI-345(analog)是一种Src抑制剂。

  • GC34119 structure
    GC341191-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride)
    CAS: 956025-47-1
    纯度: >99.50%

    1-Naphthyl PP1 hydrochloride 是 src 家族激酶 v-Src 的选择性抑制剂

  • GC35209 structure
    GC35209A 419259
    CAS: 364042-47-7

    An inhibitor of Src family kinases

  • GC35213 structure
    GC35213A-770041
    CAS: 869748-10-7
    纯度: >99.00%

    A LCK kinase inhibitor

  • GC35812 structure
    GC35812Dasatinib hydrochloride
    CAS: 854001-07-3
    纯度: >98.50% / >99.00%

    An inhibitor of Abl and Src

  • GC36430 structure
    GC36430Lck inhibitor 2
    CAS: 944795-06-6
    纯度: >98.00%

    Lck inhibitor 2是多靶点酪氨酸激酶抑制剂，对Lck，Btk，Lyn，Btk和Txk的IC50分别为13nM，9nM，3nM，26nM和2nM。

  • GC36546 structure
    GC36546Masitinib mesylate
    CAS: 1048007-93-7
    纯度: >99.50%

    An inhibitor of c-Kit

  • GC37620 structure
    GC37620Secretin, canine
    CAS: 110786-77-1

    Secretin, canine 是一种内分泌激素，刺激分泌富含碳酸氢盐的胰液。Secretin, canine 可通过Src激酶依赖途径调节胃单层细胞的主要细胞功能和旁细胞通透性。

  • GC37771 structure
    GC37771TG 100572
    CAS: 867334-05-2

    TG 100572是多靶点激酶抑制剂，抑制受体酪氨酸激酶 (receptor tyrosine kinases) 和Src激酶 (Src kinases); 对VEGFR1，VEGFR2，FGFR1，FGFR2，PDGFRβ，Fgr，Fyn，Hck，Lck，Lyn，Src，Yes 的 IC50 值分别为2，7，2，16，13，5，0.5，6，0.1，0.4，1，0.2 nM。

  • GC37772 structure
    GC37772TG 100572 Hydrochloride
    CAS: 867331-64-4
    纯度: >99.50%

    TG 100572 Hydrochloride 是多靶点激酶抑制剂，抑制受体酪氨酸激酶 (receptor tyrosine kinases) 和Src激酶 (Src kinases); 对VEGFR1，VEGFR2，FGFR1，FGFR2，PDGFRβ，Fgr，Fyn，Hck，Lck，Lyn，Src，Yes 的 IC50 值分别为2，7，2，16，13，5，0.5，6，0.1，0.4，1，0.2 nM。

  • GC37773 structure
    GC37773TG 100801 Hydrochloride
    CAS: 1018069-81-2

    TG 100801 Hydrochloride 是TG 100572的前药，通过去酯化产生TG 100572，开发用来治疗年龄相关的黄斑变性。TG 100572是多靶点激酶抑制剂，抑制受体酪氨酸激酶 (receptor tyrosine kinases) 和Src激酶 (Src kinases); 对VEGFR1，VEGFR2，FGFR1，FGFR2，PDGFRβ，Fgr，Fyn，Hck，Lck，Lyn，Src，Yes 的 IC50 值分别为2，7，2，16，13，5，0.5，6，0.1，0.4，1，0.2。

  • GC38006 structure
    GC38006β-Hydroxyisovalerylshikonin
    CAS: 7415-78-3
    纯度: >99.50%

    Beta-hydroxyisovalerylshikonin 是一种从Lithospermium radix 中分离出的天然产物，是一种有效的 PTK 抑制剂， 对 EGFR 和 v-Src 受体作用的 IC50 分别为 0.7 μM 和 1 μM。Beta-hydroxyisovalerylshikonin 对多种肿瘤细胞系均有抑制作用，能高效诱导 NCI-H522 和 DMS114 细胞的死亡。

  • GC38864 structure
    GC38864TL02-59
    CAS: 1315330-17-6
    纯度: >99.50%

    TL02-59 is an orally active, selective Src-family kinase Fgr inhibitor with an IC50 of 0.03 nM.

  • GC40054 structure
    GC40054CCT241161
    CAS: 1163719-91-2
    纯度: >98.00%

    A multi-kinase inhibitor

  • GC40080 structure
    GC40080Bosutinib-d8
    CAS: 2733145-45-2
    纯度: >99.00%

    An internal standard for the quantification of bosutinib

  • GC42616 structure
    GC426167-oxo Staurosporine
    CAS: 125035-83-8
    纯度: >98.00%

    An antibiotic with diverse biological activities

  • GC44583 structure
    GC44583PD 089828
    CAS: 179343-17-0
    纯度: >98.00%

    An inhibitor of EGFR, PDGFβ, FGF, and c-Src

  • GC44977 structure
    GC44977Syk Inhibitor
    CAS: 622387-85-3
    纯度: >95.00%

    Potently blocks spleen tyrosine kinase activity

  • GC45687 structure
    GC45687Dasatinib N-oxide
    CAS: 910297-52-8
    纯度: >95.00%

    A major metabolite of dasatinib

  • GC45828 structure
    GC45828Ponatinib-d8
    CAS: 1562993-37-6
    纯度: >99.00%

    An internal standard for the quantification of ponatinib

  • GC46924 structure
    GC46924BIBF 1120-13C-d3
    纯度: >99.00%

    A neuropeptide with diverse biological activities

  • GC47771 structure
    GC47771NG 25 (hydrochloride hydrate)
    纯度: >98.00%

    An inhibitor of MAP4K2 and TAK1

  • GC48992 structure
    GC48992CGP 77675 (hydrate)
    纯度: >98.00%

    An inhibitor of Src family kinases