GlpBio

Src

Src(Src激酶)

Src (proto-oncogene tyrosine-protein kinase) is a non-receptor protein tyrosine kinase family including 9 members and promotes survival, angiogenesis, proliferation and invasion pathways.

Src 相关产品(101)

  • GC10222 structure
    GC10222KX2-391 dihydrochloride
    CAS: 1038395-65-1
    纯度: >98.00%

    A Src kinase inhibitor

  • GC10344 structure
    GC10344PP 2 (AG 1879)
    CAS: 172889-27-9
    纯度: >98.50%

    PP 2 (AG 1879)是一种选择性Src家族激酶抑制剂。PP 2抑制Lck和Fyn的半数抑制浓度（IC 50 ）分别为0.004μM和0.005μM。

  • GC12185 structure
    GC12185ZM 306416
    CAS: 690206-97-4
    纯度: >99.50%

    A VEGF receptor kinase inhibitor

  • GC13102 structure
    GC13102XL228
    CAS: 898280-07-4
    纯度: >99.00%

    A tyrosine kinase inhibitor

  • GC13343 structure
    GC13343Bosutinib (SKI-606)
    CAS: 380843-75-4
    纯度: >99.50%

    An inhibitor of Src and Abl kinases

  • GC14332 structure
    GC14332NVP-BHG712
    CAS: 940310-85-0
    纯度: >99.50%

    A selective EphB4 kinase inhibitor

  • GC14807 structure
    GC14807Fingolimod (FTY720) HCl
    CAS: 162359-56-0
    纯度: >99.50% / >99.00%

    芬戈莫德(FTY720)是一种免疫抑制剂,通常用于治疗多发性硬化症,也有抗癌作用,可以作为HDACi(组蛋白脱乙酰酶抑制剂)。

  • GC15197 structure
    GC15197Saracatinib (AZD0530)
    CAS: 379231-04-6
    纯度: >99.50% / >99.00%

    A dual inhibitor of c-Src and Abl

  • GC17990 structure
    GC17990PP 1
    CAS: 172889-26-8
    纯度: >98.50%

    PP 1是一种新型的高效、选择性Src家族酪氨酸激酶抑制剂，PP 1有效抑制Lck（IC 50 =5nM）和Fyn（IC 50 =6nM）的磷酸化来阻断T细胞受体信号通路。

  • GA23328 structure
    GA23328Osteogenic Growth Peptide (10-14)
    CAS: 105250-85-9
    纯度: >99.50% / >98.00%

    Osteogenic Growth Peptide (10-14)是具有活性的成骨生长肽（OGP）的C端截短的五肽片段，是一种Src kinase（Src）抑制剂。

  • GC10048 structure
    GC10048MNS
    CAS: 1485-00-3

    An inhibitor of Src, Syk, and platelet aggregation

  • GC10775 structure
    GC10775MLR 1023
    CAS: 41964-07-2
    纯度: >99.50%

    An allosteric Lyn kinase activator

  • GC11003 structure
    GC11003PP121
    CAS: 1092788-83-4
    纯度: >99.00%

    A potent dual inhibitor of tyrosine and phosphoinositide kinases

  • GC11526 structure
    GC11526N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide
    CAS: 190078-50-3

    Phosphopeptide for binding to the src SH2 domain

  • GC11622 structure
    GC11622TG 100801
    CAS: 867331-82-6
    纯度: >98.00%

    TG 100801 是一种前药，可通过在开发过程中的去酯化作用产生 TG 100572，以治疗年龄相关性黄斑变性。 TG 100572 是一种多靶点激酶抑制剂，可抑制受体酪氨酸激酶和 Src 激酶；对于 VEGFR1、VEGFR2、FGFR1、FGFR2、PDGFRβ、Fgr、Fyn、Hck、Lck、Lyn、Src、Yes ， 分别。

  • GC12145 structure
    GC12145ENMD-2076 L-(+)-Tartaric acid
    CAS: 1291074-87-7
    纯度: >98.50%

    ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂，对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。

  • GC12172 structure
    GC121721-Naphthyl PP1
    CAS: 221243-82-9
    纯度: >98.50%

    Inhibitor of modified ‘analog-sensitive’ kinases

  • GC12746 structure
    GC12746N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu
    CAS: 159439-02-8

    Phosphopeptide ligand for the src SH2 domain

  • GC12958 structure
    GC12958ER 27319 maleate
    CAS: 1204480-26-1
    纯度: >99.00%

    Syk激酶的选择性抑制剂

  • GC13117 structure
    GC13117Lck Inhibitor
    CAS: 847950-09-8
    纯度: >98.50%

    A selective inhibitor of lymphocyte-specific protein tyrosine kinase

  • GC13410 structure
    GC13410Masitinib (AB1010)
    CAS: 790299-79-5
    纯度: >99.50%

    An inhibitor of c-Kit

  • GC13592 structure
    GC13592PD173955
    CAS: 260415-63-2
    纯度: >99.00%

    A tyrosine kinase inhibitor

  • GC13600 structure
    GC13600WH-4-023
    CAS: 837422-57-8
    纯度: >98.00%

    An inhibitor of Lck and Src

  • GC13797 structure
    GC13797PP 3
    CAS: 5334-30-5

    A negative control for Src tyrosine kinase inhibitors