Endogenous Metabolite
Endogenous Metabolite(内源性代谢物)
Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.
Endogenous Metabolite 相关产品(1712)
- GN10184Oleanolic acidCAS: 508-02-1纯度: >98.00%
Oleanolic acid齐墩果酸是一种天然的五环三萜，长期以来一直被用作治疗肝炎的有效药物。齐墩果酸对多种癌症也有抗肿瘤作用。
- GN10227Sodium DemethylcantharidateCAS: 13114-29-9
Extracted from Mylabris phqlarata pallas;Store the product in sealed, cool and dry condition
- GN10285TheobromineCAS: 83-67-0纯度: >99.00%
A methylxanthine alkaloid with diverse biological activities
- GN10289TrigonellineCAS: 535-83-1纯度: >99.50%
Trigonelline是一种从 Trigonella foenum-graecum L 或 Leonurus artemisia 中分离出来的生物碱，是一种强效且特异性的Nrf2抑制剂。
- GN10342Chondroitin sulfate (from bovine)CAS: 9007-28-7纯度: >98.00% / >95.00%
Chondroitin sulfate (from bovine)是从牛软骨中提取的天然多糖。
- GN10347Nicotinamide (Vitamin B3)CAS: 98-92-0纯度: >99.50%
Nicotinamide (Vitamin B3)是维生素B3的酰胺衍生物，可以抑制SIRT1（IC 50 ：50-180μM）和SIRT2（IC 50 ：2μM）的活性。Nicotinamide还可增加细胞中NAD + 、ATP、ROS水平。
- GN10506UmbelliferoneCAS: 93-35-6纯度: >99.00% / >98.50% / >99.50%
A derivative and metabolite of coumarin with diverse biological activities
- GN10540Fumalic acidCAS: 1135-24-6纯度: >99.00%
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong.
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GN10146 | Butane diacid | 110-15-6 | >98.00% | |
丁烷二酸是一种有效且具有口服活性的抗焦虑剂。 | ||||
| GN10184 | Oleanolic acid | 508-02-1 | >98.00% | |
Oleanolic acid齐墩果酸是一种天然的五环三萜，长期以来一直被用作治疗肝炎的有效药物。齐墩果酸对多种癌症也有抗肿瘤作用。 | ||||
| GN10190 | Cinnamic acid | 140-10-3 | >99.50% | |
肉桂酸是一种天然抗菌剂，对鱼类病原体 A 的最低抑菌浓度 (MIC) 为 250 μg/mL。 | ||||
| GN10227 | Sodium Demethylcantharidate | 13114-29-9 | - | |
Extracted from Mylabris phqlarata pallas;Store the product in sealed, cool and dry condition | ||||
| GN10285 | Theobromine | 83-67-0 | >99.00% | |
A methylxanthine alkaloid with diverse biological activities | ||||
| GN10289 | Trigonelline | 535-83-1 | >99.50% | |
Trigonelline是一种从 Trigonella foenum-graecum L 或 Leonurus artemisia 中分离出来的生物碱，是一种强效且特异性的Nrf2抑制剂。 | ||||
| GN10290 | Norcantharidin | 29745-04-8 | - | |
An inhibitor of PP1 and PP2A | ||||
| GN10306 | Folic acid | 59-30-3 | >99.50% / >98.00% | |
An essential B vitamin | ||||
| GN10342 | Chondroitin sulfate (from bovine) | 9007-28-7 | >98.00% / >95.00% | |
Chondroitin sulfate (from bovine)是从牛软骨中提取的天然多糖。 | ||||
| GN10347 | Nicotinamide (Vitamin B3) | 98-92-0 | >99.50% | |
Nicotinamide (Vitamin B3)是维生素B3的酰胺衍生物，可以抑制SIRT1（IC 50 ：50-180μM）和SIRT2（IC 50 ：2μM）的活性。Nicotinamide还可增加细胞中NAD + 、ATP、ROS水平。 | ||||
| GN10349 | Ergosterol | 57-87-4 | - | |
A fungal sterol | ||||
| GN10382 | Xylitol | 87-99-0 | >98.00% | |
木糖醇是一种化学物质，归类为多元醇或糖醇。 | ||||
| GN10423 | Lipoic acid | 62-46-4 | >99.50% | |
硫辛酸 ((R)-(+)-α-硫辛酸) 是一种抗氧化剂，是线粒体酶复合物的重要辅助因子。 | ||||
| GN10470 | Eriodictyol | 552-58-9;4049-38-1 | >99.50% | |
圣草酚是一种从中药中分离出来的黄酮类化合物，具有抗氧化和抗炎活性。 | ||||
| GN10489 | Hyodeoxycholic acid | 83-49-8 | >99.00% | |
A secondary bile acid | ||||
| GN10492 | Allantoin | 97-59-6 | >99.50% | |
A product of purine and uric acid metabolism | ||||
| GN10506 | Umbelliferone | 93-35-6 | >99.00% / >98.50% / >99.50% | |
A derivative and metabolite of coumarin with diverse biological activities | ||||
| GN10518 | Chitosamine hydrochloride | 66-84-2 | >98.00% | |
An amino monosaccharide | ||||
| GN10540 | Fumalic acid | 1135-24-6 | >99.00% | |
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong. | ||||
| GN10552 | Syringic acid | 530-57-4 | >98.00% | |
A natural O-methylated phenolic acid | ||||
| GN10554 | Phytic acid | 83-86-3 | - | |
Phytic acid 是一种天然存在于豆科植物种子中的抗营养素。 | ||||
| GN10555 | Bilirubin | 635-65-4 | >98.50% / >99.00% | |
Bilirubin是血红素分解代谢产生的黄色终产物，可抑制ADAMTS13对F485-rVWF73-H、D633-rVWF73-H和GST-rVWF71-11K的切割活性，IC 50 值分别为13μM、70μM和17μM。 | ||||
| GN10558 | L-Carnitine inner salt (Standard) | 541-15-1 | >98.00% | |
A conditionally essential nutrient | ||||
| GN10622 | Shikimic acid | 138-59-0 | >99.50% | |
A cyclohexenecarboxylic acid | ||||