GlpBio

Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite 相关产品(1712)

  • GC61354 structure
    GC61354Trimethylamine N-oxide dihydrate
    CAS: 62637-93-8
    纯度: >98.00%

    A metabolite of choline, phosphatidylcholine, and L-carnitine

  • GC61424 structure
    GC61424Phenylglyoxylic acid
    CAS: 611-73-4
    纯度: >98.50%

    Phenylglyoxylic acid (Benzoyl formate, Phenylglyoxalic acid, Phenylglyoxylate) is a key building block in the field of chemical synthesis and is widely used to synthesize pharmaceutical intermediates or food additives.

  • GC61431 structure
    GC61431DL-Asparagine
    CAS: 3130-87-8
    纯度: >98.00%

    DL-Asparagine是L-Aparagine和D-Aparagine对映异构体的外消旋混合物。DL-Asparagine可以用于细菌的生长培养基中。

  • GC61436 structure
    GC61436Gallic acid hydrate
    CAS: 5995-86-8
    纯度: >98.00%

    A phenol with diverse biological activities

  • GC61442 structure
    GC614421-Methylguanidine hydrochloride
    CAS: 21770-81-0
    纯度: >98.00%

    Methylguanidine is a guanidine compound deriving from protein catabolism.

  • GC61443 structure
    GC61443Thiamine monophosphate chloride (dihydrate)
    CAS: 273724-21-3
    纯度: >98.00% / >99.00%

    Thiamine monophosphate chloride dihydrate (Vitamin B1 Monophosphate Chloride, Sineurina, Phosphothiamine) is an endogenous metabolite.

  • GC61448 structure
    GC61448ATP disodium trihydrate
    CAS: 51963-61-2
    纯度: >98.00%

    ATP Disodium (Adenosine-Triphosphate disodium, ATP disodium salt, Adenosine 5'-triphosphate) is a disodium salt form of adenosine-triphosphate which is a multifunctional nucleoside triphosphate.

  • GC61460 structure
    GC61460Dihydroxyacetone phosphate hemimagnesium hydrate
    纯度: >95.00%

    Dihydroxyacetonephosphate在脂质生物合成和糖酵解中是重要的中间产物。它是一种参与多种代谢途径的生化化合物，包括植物的卡尔文循环和糖酵解。Dihydroxyacetonephosphate被发现与醛缩酶缺乏有关，这是一种先天性代谢错误。

  • GC61482 structure
    GC61482sn-Glycerol 3-phosphate lithium
    纯度: >98.00% / >95.00% / >99.00%

    sn-Glycerol3-phosphatelithium是由胞质甘油3-磷酸脱氢酶途径产生的，利用糖酵解过程中形成的NADH减少二羟丙酮磷酸。

  • GC61487 structure
    GC61487all-trans-Anhydro Retinol
    CAS: 1224-78-8
    纯度: >90.00%

    all-trans-AnhydroRetinol(AnhydrovitaminA)是维生素A的代谢产物。all-trans-AnhydroRetinol用于合成的多种维生素制剂。

  • GC61494 structure
    GC61494D-Sedoheptulose 7-phosphate
    CAS: 2646-35-7
    纯度: >95.00%

    An intermediate in the pentose phosphate pathway

  • GC61496 structure
    GC61496Angiotensin (1-7) (acetate)
    CAS: 2855063-75-9
    纯度: >98.50%

    Angiotensin (1-7) (Ang-(1-7), Angiotensin fragment 1-7) is a bioactive component of the renin-angiotensin system that is formed endogenously from either Ang I or Ang II. Angiotensin (1-7) is a canine ACE inhibitor with an IC50 of 0.65 μM and inhibits the activity mediated by myostatin through Mas receptor.

  • GC61538 structure
    GC6153811-Oxo etiocholanolone
    CAS: 739-27-5
    纯度: >96.00%

    11-oxo Etiocholanolone 是皮质醇和 11-酮睾酮的代谢产物。由皮质醇经可的松和四氢可的酮中间体形成，由11-酮睾酮经5β-11-酮二氢睾酮和3α-11-酮基胆二醇中间体形成.?妊娠期间 11-氧代胆烷醇酮的尿液水平升高，并且在子宫平滑肌瘤患者中升高。11-氧代胆烷醇酮的粪便水平已被用作家畜和散养反刍动物压力的标志物。

  • GC61604 structure
    GC61604Guanylin(human) TFA
    纯度: >97.00%

    Guanylin(human)TFA，一种15个氨基酸的肽，是一种内源性肠鸟苷酸环化酶(intestinalguanylatecyclase)激活剂。Guanylin(human)TFA主要存在于胃肠道中，其通过cGMP依赖性机制调节肠和肾上皮中电解质水的运输。

  • GC61614 structure
    GC61614Succinyladenosine
    CAS: 4542-23-8
    纯度: >99.00%

    Succinyladenosine，是胞内腺苷酸(S-AMP)经5-核苷酸酶脱磷酸化的产物，是腺苷酸琥珀酸酶(ASL)缺乏的生化标志。

  • GC61647 structure
    GC61647(+)-Longifolene
    CAS: 475-20-7
    纯度: >90.00%

    (+)-Longifolene is a naturally occurring, oily liquid hydrocarbon found primarily in the high-boiling fraction of certain pine resins

  • GC61691 structure
    GC61691Arabinose
    CAS: 147-81-9
    纯度: >98.00%

    Arabinose是一种内源性代谢产物。

  • GC61695 structure
    GC61695L-Uridine
    CAS: 26287-69-4
    纯度: >99.50%

    L-Uridine分离自PolyporaceaefungusPoriacocos(Schw.)，是正常RNA成分中的D-尿苷的对映异构体。L-Uridine充当核苷磷酸转移酶的磷酸受体。

  • GC61703 structure
    GC61703DL-Glutamic acid
    CAS: 617-65-2

    DL-谷氨酸是作为基本代谢产物的谷氨酸的共轭酸。与多晶型物α和βL-谷氨酸的第二相相比，DL-谷氨酸具有更好的稳定性。

  • GC61716 structure
    GC617163,5-Dimethylbenzaldehyde
    CAS: 5779-95-3

    3,5-Dimethylbenzaldehyde是一种化学合成中的分子砌块。

  • GC61736 structure
    GC61736D-Ribose 5-phosphate disodium dihydrate
    CAS: 207671-46-3
    纯度: >99.00%

    D-Ribose5-phosphatedisodiumdihydrate是戊糖磷酸途径(PPP)氧化分支的中间产物，是PPP非氧化分支的最终产物。D-Ribose5-phosphate用于核苷酸和核酸的合成。

  • GC61759 structure
    GC61759(R)-3-Hydroxybutanoic acid sodium
    CAS: 13613-65-5
    纯度: >97.00%

    (R)-3-Hydroxybutanoic acid sodium是血液或脑组织中的代谢产物，可参与能量供应途径。

  • GC61792 structure
    GC61792Cyclic ADP-ribose ammonium
    纯度: >99.00%

    An endogenous Ca 2+ mobilizer

  • GC61797 structure
    GC61797L-Palmitoylcarnitine TFA
    纯度: >98.00%

    L-PalmitoylcarnitineTFA是一种长链酰基肉碱和脂肪酸代谢产物，在缺血期间积聚于肌膜并扰乱膜脂环境。L-PalmitoylcarnitineTFA通过与Kir6.2的相互作用抑制KATP通道活性，而不影响单通道电导。