D-Sedoheptulose-7-phosphate is an intermediate in the pentose phosphate pathway.1,2 In this pathway, transaldolase catalyzes the transfer of a three carbon dihydroxyacetone moiety from D-sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to generate D-fructose-6-phosphate. D-Sedoheptulose-7-phosphate is also an intermediate in carbon fixation in photosynthetic organisms, as well as in the biosynthesis of lipopolysaccharide, amino acids, secondary metabolites, and antibiotics.3
1.Gumaa, K.A., and McLean, P.The pentose phosphate pathway of glucose metabolism: Enzyme profiles and transient and steady-state content of intermediates of alternative pathways of glucose metabolism in Krebs ascites cellsBiochem. J.115(5)1009-1029(1969) 2.Patra, K.C., and Hay, N.The pentose phosphate pathway and cancerTrends Biochem. Sci.39(8)347-354(2014) 3.Wolosiuk, R.A., Ballicora, M.A., and Hagelin, K.The reductive pentose phosphate cycle for photosynthetic CO2 assimilation: Enzyme modulationFASEB J.7(8)622-637(1993)