GlpBio

Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite 相关产品(1712)

  • GC39480 structure
    GC39480Bisphenol A
    CAS: 80-05-7
    纯度: >99.50%

    Bisphenol A是一种酚类有机合成化合物，是合成塑料（主要是某些聚碳酸酯和环氧树脂）、聚砜的原料。

  • GC39527 structure
    GC395272-O-Methylcytosine
    CAS: 3289-47-2
    纯度: >95.00%

    2-O-Methylcytosine，一种 O-烷基化类似物和 DNA 的加合物，属于受损的核碱基。

  • GC39533 structure
    GC39533Cinnamoylglycine
    CAS: 16534-24-0
    纯度: >95.00%

    Cinnamoylglycine 是人体尿液代谢物，一种肉桂酸和的甘氨酸结合物。Cinnamoylglycine 被用作的尿液标志物，可以用作在抗生素治疗期之后定殖耐药性的标志物。

  • GC39539 structure
    GC39539Moracin M
    CAS: 56317-21-6
    纯度: >98.50%

    Moracin M是一种磷酸二酯酶4（PDE4）抑制剂（PDE4D2：IC 50 = 2.9μM；PDE4B2：IC 50 = 4.5μM；PDE5A1：IC 50 > 40μM；PDE9A2：IC 50 > 100μM）。

  • GC39550 structure
    GC39550Pi-Methylimidazoleacetic acid hydrochloride
    CAS: 1071661-55-6
    纯度: >99.00%

    Pi-Methylimidazoleacetic acid hydrochloride 是一种潜在的神经毒素。

  • GC39617 structure
    GC39617Estrone sulfate potassium
    CAS: 1240-04-6
    纯度: >99.00%

    Estrone sulfate potassium 是一种天然的内源性类固醇，是雌激素酯和缀合物。

  • GC39652 structure
    GC39652D-α-Tocopherol acetate
    CAS: 58-95-7
    纯度: >98.00%

    Vitamin E Acetate (Tocopherol) is the stable form of Vitamin E most often used in cosmetic formulations for its skin care benefits. It protects the cells against free radicals and prevents the peroxidation of body fats as an in-vivo antioxidant.

  • GC39659 structure
    GC39659Iretol
    CAS: 487-71-8
    纯度: >99.00%

    Iretol (2,4,6-trihydroxyanisole) 是一种从 Iris Jorentina 中获得的葡糖苷的降解产物。Iretol 是一种合成天然异黄酮的中间体，例如 Tectorigenin，Irigenin 和 Caviunin。

  • GC39670 structure
    GC39670Cholic acid sodium
    CAS: 361-09-1
    纯度: >98.00%

    A primary bile acid

  • GC39672 structure
    GC39672Sodium 2-hydroxybutanoate
    CAS: 5094-24-6
    纯度: >97.00% / >98.00%

    Sodium 2-hydroxybutanoate (Sodium 2-hydroxybutyrate, Sodium DL-2-hydroxybutyrate), converted from 2-Aminobutyric acid, is an intermediate metabolite.

  • GC39686 structure
    GC396862,2-Dihydroxyacetic acid
    CAS: 563-96-2
    纯度: >95.00%

    Glyoxylic acid monohydrate (2,2-Dihydroxyacetic acid) is an atmospherically relevant ketoacid.

  • GC39688 structure
    GC396883-Amino-2-piperidinone
    CAS: 1892-22-4
    纯度: >98.00%

    3-aminopiperidine-2-one 是所有活生物体中有的代谢产物。3-aminopiperidine-2-one 是一种 δ-内酰胺，其是在位置 3 被氨基取代的 2-哌啶酮。

  • GC39690 structure
    GC396903-Methyl-2-buten-1-ol
    CAS: 556-82-1

    3-Methyl-2-buten-1-ol (Prenol, Prenyl alcohol, Dimethylallyl alcohol) is an endogenous metabolite.

  • GC39691 structure
    GC396914-Hydroxymethylpyrazole
    CAS: 25222-43-9
    纯度: >98.00%

    4-Hydroxymethylpyrazole 是 Fomepizole 的初级代谢产物。Fomepizole 是一种竞争的乙醇脱氢酶抑制剂。

  • GC39702 structure
    GC39702Copper tripeptide
    CAS: 89030-95-5
    纯度: >99.00%

    Copper tripeptide (GHK-Cu) 是一种天然存在的三肽，首先从人血浆中分离，但也可以在唾液和尿液中发现。在伤口愈合期间，Copper tripeptide 可以通过蛋白水解从现有的细胞外蛋白质中除去，并且用作炎性和内皮细胞的化学引诱物。Copper tripeptide 可以增加成纤维细胞中胶原蛋白，弹性蛋白，蛋白多糖和糖胺聚糖中信使 RNA 的产生。Copper tripeptide 是皮肤再生中多种细胞途径的天然调节剂。

  • GC39729 structure
    GC39729trans-Cinnamaldehyde
    CAS: 14371-10-9
    纯度: >99.00%

    Cinnamaldehyde is a flavonoid that is naturally synthesized by the shikimate pathway. Its supplementation can improve glucose and lipid homeostasis in diabetic animals; a TRPA1 agonist.

  • GC39761 structure
    GC397612-Mercaptobenzothiazole
    CAS: 149-30-4
    纯度: >98.00%

    2-Mercaptobenzothiazole (Benzothiazole-2-thiol, 2-MBT, Mercapto-2-benzothiazole) is an exceptionally potent inhibitor of banana polyphenoloxidase and can significantly delay the onset of substrate oxidation at concentrations as low as 100 nM.

  • GC39766 structure
    GC397661,2-Cyclohexanedione
    CAS: 765-87-7

    1,2-环己二酮（1,2-Cyclohexanedione）是一种有机化合物，是三种同分异构的环己二酮之一。它是一种无色化合物，可溶于多种有机溶剂。由二氧化硒氧化环己酮而得

  • GC39767 structure
    GC397672,6-Dihydroxyacetophenone
    CAS: 699-83-2
    纯度: >98.50%

    2,6-Dihydroxyacetophenone 是一种内源性代谢产物。

  • GC39768 structure
    GC397682,6-Dimethylhydroquinone
    CAS: 654-42-2
    纯度: >98.00%

    2,6-Dimethylhydroquinone 是一种内源性代谢产物。

  • GC39769 structure
    GC39769Tyramine hydrochloride
    CAS: 60-19-5
    纯度: >98.00%

    A monoamine and TAAR1 agonist

  • GC39772 structure
    GC397722,4-Dihydroxybenzaldehyde
    CAS: 95-01-2

    2,4-Dihydroxybenzaldehyde 是一种内源性代谢产物。

  • GC39773 structure
    GC397732,6-Dibromophenol
    CAS: 608-33-3
    纯度: >98.00%

    2,6-Dibromophenol 是一种内源性代谢产物。

  • GC39776 structure
    GC397762-Methylacetophenone
    CAS: 577-16-2
    纯度: >98.50%

    2-Methylacetophenone 是一种内源性代谢产物。