GlpBio

Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite 相关产品(1712)

  • GC30613 structure
    GC306135-Hydroxydopamine hydrochloride
    CAS: 5720-26-3
    纯度: >95.00%

    5-Hydroxydopamine是人尿液中天然存在的胺。

  • GC30615 structure
    GC30615Nicotinuric acid
    CAS: 583-08-4

    A metabolite of niacin

  • GC30616 structure
    GC306163-Hydroxybutyric acid
    CAS: 300-85-6
    纯度: >95.00% / >98.50%

    3-羟基丁酸（3-Hydroxybutyric acid，D-β-hydroxybutyrate，BHB）是一类组蛋白脱乙酰酶（HDAC）的内源性和特异性抑制剂，抑制HDAC1、HDAC3和HDAC4的IC50分别为5.3、2.4和4.5 mM。

  • GC30617 structure
    GC30617Tetradecanoylcarnitine
    CAS: 25597-07-3

    Tetradecanoylcarnitine是人体中的肉毒碱，参与长链脂肪酸的β型氧化。

  • GC30618 structure
    GC30618Orotidine
    CAS: 314-50-1
    纯度: >90.00% / >95.00%

    Orotidine是一种由核糖和orotic acid组成的嘧啶核苷，可在尿液排泄物中发现。

  • GC30620 structure
    GC30620D(+)-Raffinose pentahydrate (D-Raffinose pentahydrate)
    CAS: 17629-30-0
    纯度: >98.00%

    A natural trisaccharide

  • GC30622 structure
    GC306222-Oxo-3-phenylpropanoic acid
    CAS: 156-06-9
    纯度: >99.00%

    2-Oxo-3-phenylpropanoic acid (Phenylpyruvic acid) is used in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase.

  • GC30623 structure
    GC30623(S)-3-Hydroxyisobutyric acid
    CAS: 2068-83-9
    纯度: >93.00%

    (S)-3-Hydroxyisobutyric acid 是一种重要的器官间代谢物，是 l-缬氨酸和胸腺嘧啶途径的中间体，也是良好的糖异生底物。

  • GC30624 structure
    GC30624L-Alloisoleucine ((3R)-LS-Isoleucine)
    CAS: 1509-34-8
    纯度: >98.00%

    A branched-chain amino acid

  • GC30629 structure
    GC306292-Oxobutanoic acid
    CAS: 600-18-0

    2-Oxobutanoic acid (2-Oxobutyrate, 2-ketobutyric acid, 2-oxobutyric acid, alpha-ketobutyric acid, α-ketobutyric acid) is a substance that is involved in the metabolism of many amino acids as well as propanoate metabolism and C-5 branched dibasic acid metabolism.

  • GC30630 structure
    GC306304-Guanidinobutanoic acid
    CAS: 463-00-3
    纯度: >98.00%

    4-Guanidinobutanoate (4-Guanidinobutanoate, gamma-Guanidinobutyric acid, gamma-Guanidinobutanoate) is a normal metabolite present in low concentrations.

  • GC30631 structure
    GC30631Paullinic acid
    CAS: 17735-94-3
    纯度: >95.00%

    An ω-7 fatty acid

  • GC30632 structure
    GC30632Dodecanedioic acid
    CAS: 693-23-2
    纯度: >98.00%

    Dodecanedioic acid is a dicarboxylic acid mainly used in antiseptics, top-grade coatings, painting materials, corrosion inhibitors, surfactants, and engineering plastics.

  • GC30635 structure
    GC306353-Methylxanthine
    CAS: 1076-22-8
    纯度: >99.50%

    A cGMP PDE inhibitor and metabolite of theophylline and caffeine

  • GC30636 structure
    GC306363-Hydroxypicolinic acid (Picolinic acid, 3-hydroxy- (6CI,7CI,8CI))
    CAS: 874-24-8

    A matrix substance for MALDI-MS

  • GC30638 structure
    GC306383-Hydroxymandelic Acid
    CAS: 17119-15-2

    3-HydroxymandelicAcid是Phenylephrine的代谢物，Phenylephrine是α受体(α-receptor)的激动剂。

  • GC30640 structure
    GC30640Homogentisic acid
    CAS: 451-13-8
    纯度: >97.00%

    An intermediate in aromatic amino acid metabolism

  • GC30641 structure
    GC306411-Naphthol (Fourrine ERN)
    CAS: 90-15-3
    纯度: >98.00%

    1-萘酚（1-Naphthol）用于制造染料、中间体、合成香料，是一种激发态质子转移 (ESPT) 荧光分子探针

  • GC30642 structure
    GC306423-Hydroxydodecanoic acid
    CAS: 1883-13-2
    纯度: >98.00%

    A hydroxy fatty acid

  • GC30645 structure
    GC30645p-Hydroxymandelic acid
    CAS: 1198-84-1
    纯度: >97.00%

    p-Hydroxymandelicacid是一种有价值的芳香类化学品，广泛用于生产药物和食品添加剂。

  • GC30646 structure
    GC30646Skatole(3-Methylindole)
    CAS: 83-34-1
    纯度: >99.50%

    Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.

  • GC30649 structure
    GC30649(S)-3,4-Dihydroxybutyric acid
    CAS: 51267-44-8

    (S)-3,4-Dihydroxybutyricacid是一种正常的人体尿液代谢物，在琥珀酸半醛脱氢酶(SSADH)缺乏症患者中浓度增加。

  • GC30651 structure
    GC30651Decyl aldehyde
    CAS: 112-31-2
    纯度: >99.50%

    Decyl aldehyde (Decanal, Capraldehyde, Decanaldehyde) is a naturally occuring organic compound that is used in fragrances and flavoring.

  • GC30652 structure
    GC30652Melanin
    CAS: 8049-97-6
    纯度: >99.00% / >98.00%

    Melanin是一种具有多功能的生物色素，可以抵御环境压力，如紫外线(UV)，氧化剂和电离辐射。