Drug Metabolite(药物代谢物)

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products for Drug Metabolite

Cat.No. 产品名称 Information
GC43400 Dehydro Aripiprazole (hydrochloride)
脱氢阿立哌唑盐酸盐
The primary, active metabolite of aripiprazole
GC43376 Dapagliflozin-3-O-β-D-Glucuronide A metabolite of dapagliflozin
GC43371 Dabigatran Acyl-β-D-Glucuronide
达比加群酰基Β维葡糖苷酸
A major active metabolite of dabigatran
GC43343 Cyclo(L-Tyr-L-Val)
环(酪氨酸-缬氨酸)二肽,Cyclo(L-Tyr-L-Val)
A diketopiperazine fungal metabolite
GC43284 Clozapine N-oxide (hydrochloride)
CNO

A metabolite of clozapine and muscarinic DREADD agonist
GC43281 Clopidogrel Carboxylic Acid (hydrochloride)
(S)-(O-氯苯基)-6,7-二羟噻吩[3,2-C]吡啶-5(4H)-醋酸盐酸盐
A major inactive metabolite of clopidogrel
GC43278 Clindamycin Sulfoxide
克林霉素亚砜
An active metabolite of clindamycin
GC43248 Chlorzoxazone N-Glucuronide A phase II metabolite of chlorzoxazone
GC43225 Celecoxib Carboxylic Acid Acyl-β-D-Glucuronide
塞来昔布羧酸酰基-Β-D-葡糖苷酸
A metabolite of celecoxib
GC43140 Captopril Disulfide
卡托普利二硫化物,SQ 14551
A metabolite and degradation product of captopril
GC42913 Benazeprilat
苯那普利拉,CGS 14831
An ACE inhibitor
GC42887 Axitinib Sulfoxide
阿西替尼杂质A
A major inactive metabolite of axitinib
GC42879 Avanafil metabolite M4 An active metabolite of avanafil
GC42878 Avanafil metabolite M16 A major inactive metabolite of avanafil
GC42769 all-trans Retinoyl β-D-Glucuronide
(E-视黄酰基)-Β-葡糖苷酸
A metabolite of all-trans retinoic acid
GC42694 Acetaminophen sulfate (potassium salt)
4-乙酰氨基酚硫酸钾盐
An inactive metabolite of acetaminophen
GC42693 Acetaminophen Glucuronide (sodium salt)
P-乙酰氨基苯-B-D-葡萄糖酸钠盐
An inactive metabolite of acetaminophen
GC42690 Acecainide (hydrochloride)
N-盐酸乙酰普鲁卡胺
An active metabolite of procainamide
GC42667 Abacavir Carboxylate
阿巴卡韦羧酸盐
An inactive metabolite of abacavir
GC42633 9(E)-Erythromycin A oxime
红霉素肟A
A metabolite of roxithromycin
GC42626 8-hydroxy Efavirenz
8-羟基依法韦伦
A major metabolite of efavirenz
GC42608 7-hydroxy Methotrexate (sodium salt)
7-hydroxy MTX
A metabolite of methotrexate
GC42607 7-hydroxy Coumarin sulfate (potassium salt)
7-HC, 7HCS
An internal standard for the quantification of 7-hydroxy coumarin
GC42606 7-hydroxy Coumarin Glucuronide (sodium salt) A 7-hydroxy coumarin phase II metabolite
GC42586 6α-hydroxy Paclitaxel
6-羟基泰素
A metabolite of paclitaxel
GC42584 6-O-desmethyl Donepezil
6-O-去甲基多奈哌齐
An active metabolite of donepezil
GC42580 6-hydroxy Chlorzoxazone
6-.羟基氯唑沙宗,NSC 24955
6-hydroxy Chlorzoxazone是Chlorzoxazone在体内的主要代谢产物。6-hydroxy Chlorzoxazone主要通过肝脏细胞色素P450酶系统形成，在生化研究中常作为探针用于定量评估CYP2E1的活性。
GC42551 5-hydroxymethyl Tolterodine (formate)
5-羟甲基托特罗定
An active metabolite of tolterodine and fesoterodine
GC42550 5-hydroxy-6-methoxy (S)-Duloxetine
度洛西汀杂质
A metabolite of (S)-duloxetine
GC42549 5-hydroxy Thiabendazole
噻苯咪唑-5-羟基
A major metabolite of thiabendazole
GC42548 5-hydroxy Saxagliptin (hydrochloride) A major active metabolite of saxagliptin
GC42546 5-hydroxy Diclofenac
5-羟基双氯芬酸
An active metabolite of diclofenac
GC42415 4-hydroxy Valsartan
4-羟基缬沙坦
A major metabolite of valsartan
GC42409 4-hydroxy Nebivolol (hydrochloride) A major metabolite of nebivolol
GC42407 4-hydroxy Diclofenac
4′-羟基双氯芬酸
A CYP2C9 metabolite of the NSAID diclofenac
GC42405 4-hydroxy Atorvastatin (calcium salt)
4-羟基阿托伐他汀（钙盐）
A metabolite of atorvastatin
GC42402 4-hydroxy (S)-Duloxetine β-D-Glucuronide (sodium salt)
LY550408
An inactive metabolite of (S)-duloxetine
GC42401 4-hydroperoxy Cyclophosphamide
培磷酰胺,4-OOH-CY
4-hydroperoxy Cyclophosphamide（4-羟基过氧化环磷酰胺），环磷酰胺的活性代谢产物，能够交联DNA并独立于caspase受体激活诱导T细胞凋亡，通过产生活性氧（ROS）激活线粒体死亡途径。
GC42370 4-desmethoxy Omeprazole
埃索美拉唑杂质B
A potential impurity found in commercial omeprazole and esomeprazole magnesium preparations
GC42307 3-O-methyl-L-DOPA (hydrate)
3-O-甲基-L-多巴一水合物
A metabolite of L-DOPA
GC42275 3-hydroxy Desloratidine
3-羟基去氯雷他定盐酸盐
A major metabolite of desloratadine
GC42274 3-hydroxy Darifenacin
UK 148993
A metabolite of darifenacin
GC42198 3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt)
γ-Hydroxybaclofen
An inactive metabolite of baclofen
GC42189 2-oxo Clopidogrel
甲基(2-氯苯基)(2-氧代-2,6,7,7ALPHA-四氢噻吩并[3,2-C]吡啶-5(4H)-基)乙酸酯
An intermediary metabolite of clopidogrel
GC41937 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
15-KETO-比马前列素
A potential metabolite of Bimatoprost
GC41837 1,3,7-Trimethyluric Acid
1,3,7-三甲基尿酸,8-oxo Caffeine, NSC 11259
A metabolite of caffeine
GC41736 (S)-Dibutyl 3-Hydroxybutyl Phosphate
(S)TBPOH
A compound produced from tributyl phosphate
GC41722 (R,S)-Carvedilol Glucuronide
卡维地洛葡糖苷酸
A phase II metabolite of carvedilol
GC41694 (3S)-hydroxy Quinidine
(3S)-3-羟基奎尼定
An active quinidine metabolite
GC41671 (±)-Equol 4'-sulfate (sodium salt)
R,S-Equol 4'-Sulfate
A metabolite of (±)-equol