Drug Metabolite
Drug Metabolite(药物代谢物)
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
Drug Metabolite 相关产品(498)
- GC424094-hydroxy Nebivolol (hydrochloride)CAS: 2717115-85-8纯度: >98.00%
A major metabolite of nebivolol
- GC425515-hydroxymethyl Tolterodine (formate)CAS: 380636-49-7纯度: >98.00%
An active metabolite of tolterodine and fesoterodine
- GC425806-hydroxy ChlorzoxazoneCAS: 1750-45-4纯度: >97.00%
6-hydroxy Chlorzoxazone是Chlorzoxazone在体内的主要代谢产物。6-hydroxy Chlorzoxazone主要通过肝脏细胞色素P450酶系统形成，在生化研究中常作为探针用于定量评估CYP2E1的活性。
- GC426067-hydroxy Coumarin Glucuronide (sodium salt)CAS: 168286-98-4纯度: >95.00%
A 7-hydroxy coumarin phase II metabolite
- GC426077-hydroxy Coumarin sulfate (potassium salt)CAS: 1135316-80-1纯度: >98.00%
An internal standard for the quantification of 7-hydroxy coumarin
- GC42693Acetaminophen Glucuronide (sodium salt)CAS: 120595-80-4纯度: >98.00%
An inactive metabolite of acetaminophen
- GC42694Acetaminophen sulfate (potassium salt)CAS: 32113-41-0纯度: >98.00%
An inactive metabolite of acetaminophen
- GC42769all-trans Retinoyl β-D-GlucuronideCAS: 401-10-5纯度: >80.00%
A metabolite of all-trans retinoic acid
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC42405 | 4-hydroxy Atorvastatin (calcium salt) | 265989-44-4 | >90.00% | |
A metabolite of atorvastatin | ||||
| GC42407 | 4-hydroxy Diclofenac | 64118-84-9 | >97.00% | |
A CYP2C9 metabolite of the NSAID diclofenac | ||||
| GC42409 | 4-hydroxy Nebivolol (hydrochloride) | 2717115-85-8 | >98.00% | |
A major metabolite of nebivolol | ||||
| GC42415 | 4-hydroxy Valsartan | 188259-69-0 | >98.00% | |
A major metabolite of valsartan | ||||
| GC42546 | 5-hydroxy Diclofenac | 69002-84-2 | >98.00% | |
An active metabolite of diclofenac | ||||
| GC42548 | 5-hydroxy Saxagliptin (hydrochloride) | - | >95.00% | |
A major active metabolite of saxagliptin | ||||
| GC42549 | 5-hydroxy Thiabendazole | 948-71-0 | - | |
A major metabolite of thiabendazole | ||||
| GC42550 | 5-hydroxy-6-methoxy (S)-Duloxetine | 741693-79-8 | >95.00% | |
A metabolite of (S)-duloxetine | ||||
| GC42551 | 5-hydroxymethyl Tolterodine (formate) | 380636-49-7 | >98.00% | |
An active metabolite of tolterodine and fesoterodine | ||||
| GC42580 | 6-hydroxy Chlorzoxazone | 1750-45-4 | >97.00% | |
6-hydroxy Chlorzoxazone是Chlorzoxazone在体内的主要代谢产物。6-hydroxy Chlorzoxazone主要通过肝脏细胞色素P450酶系统形成，在生化研究中常作为探针用于定量评估CYP2E1的活性。 | ||||
| GC42584 | 6-O-desmethyl Donepezil | 120013-56-1 | >98.00% | |
An active metabolite of donepezil | ||||
| GC42586 | 6α-hydroxy Paclitaxel | 153212-75-0 | >95.00% | |
A metabolite of paclitaxel | ||||
| GC42606 | 7-hydroxy Coumarin Glucuronide (sodium salt) | 168286-98-4 | >95.00% | |
A 7-hydroxy coumarin phase II metabolite | ||||
| GC42607 | 7-hydroxy Coumarin sulfate (potassium salt) | 1135316-80-1 | >98.00% | |
An internal standard for the quantification of 7-hydroxy coumarin | ||||
| GC42608 | 7-hydroxy Methotrexate (sodium salt) | - | >96.00% | |
A metabolite of methotrexate | ||||
| GC42626 | 8-hydroxy Efavirenz | 205754-33-2 | >98.00% | |
A major metabolite of efavirenz | ||||
| GC42633 | 9(E)-Erythromycin A oxime | 111321-02-9 | >95.00% | |
A metabolite of roxithromycin | ||||
| GC42667 | Abacavir Carboxylate | 384380-52-3 | >95.00% | |
An inactive metabolite of abacavir | ||||
| GC42690 | Acecainide (hydrochloride) | 34118-92-8 | >98.00% | |
An active metabolite of procainamide | ||||
| GC42693 | Acetaminophen Glucuronide (sodium salt) | 120595-80-4 | >98.00% | |
An inactive metabolite of acetaminophen | ||||
| GC42694 | Acetaminophen sulfate (potassium salt) | 32113-41-0 | >98.00% | |
An inactive metabolite of acetaminophen | ||||
| GC42769 | all-trans Retinoyl β-D-Glucuronide | 401-10-5 | >80.00% | |
A metabolite of all-trans retinoic acid | ||||
| GC42878 | Avanafil metabolite M16 | 2748151-94-0 | >95.00% | |
A major inactive metabolite of avanafil | ||||
| GC42879 | Avanafil metabolite M4 | - | >98.00% | |
An active metabolite of avanafil | ||||