GlpBio

Glucosidase

Glucosidase(葡萄糖苷酶)

Glucosidases are glycoside hydrolase enzymes.

α-glucosidase is a glucosidase located in the brush border of the small intestine that acts upon α(1→4) bonds. α-Glucosidase inhibitor is a new type of antidiabetics. By reducing the postprandial blood sugar concentration, it can effectively control the blood sugar levels, thereby reducing the occurrence of diabetic complications.

β-glucosidase catalyzes the hydrolysis of the glycosidic bonds to terminal non-reducing residues in β-D-glucosides and oligosaccharides, with release of glucose. β-Glucosidase has attracted substantial attention in the scientific community because of its pivotal role in cellulose degradation, glycoside transformation and many other industrial processes. β-glucosidases catalyze the final step of cellulose hydrolysis and are essential in cellulose degradation.

Glucosidase 相关产品(47)

  • GC18007 structure
    GC18007Voglibose
    CAS: 83480-29-9
    纯度: >98.00%

    An α-glucosidase inhibitor

  • GC18058 structure
    GC18058Conduritol B epoxide
    CAS: 6090-95-5
    纯度: >97.00%

    An irreversible inhibitor of glucocerebrosidase

  • GC30277 structure
    GC302774',5-Dihydroxyflavone
    CAS: 6665-67-4

    4',5-Dihydroxyflavone inhibits soybean LOX-1 and yeast α-glucosidase.

  • GC30637 structure
    GC30637N-Methylmoranoline (MOR 14)
    CAS: 69567-10-8

    An inhibitor of glycoprotein processing and α-glucosidases

  • GC31580 structure
    GC31580Cefetrizole
    CAS: 65307-12-2

    Ceftezole是一种α-Glucosidase抑制剂，其IC50和Ki值分别为2.1μM和0.578μM。

  • GC32074 structure
    GC32074Celgosivir hydrochloride (MBI 3253 (hydrochloride))
    CAS: 141117-12-6
    纯度: >98.00%

    Celgosivir hydrochloride (MBI 3253 (hydrochloride)) (MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride) 是一种 α-葡萄糖苷酶 I 抑制剂；体外试验中抑制牛病毒性腹泻病毒 (BVDV)，IC50 为 1.27 μM。

  • GC32191 structure
    GC32191Celgosivir (MBI 3253)
    CAS: 121104-96-9

    Celgosivir (MBI 3253) (MBI 3253; MDL 28574; MX3253) 是一种 α-葡萄糖苷酶 I 抑制剂；体外试验中抑制牛病毒性腹泻病毒 (BVDV)，IC50 为 1.27 μM。

  • GC34835 structure
    GC34835Terphenyllin
    CAS: 52452-60-5

    A fungal metabolite with antibacterial properties

  • GC35553 structure
    GC35553Brevifolincarboxylic acid
    CAS: 18490-95-4
    纯度: >99.50%

    A phenol with anticancer and anti-inflammatory activities

  • GC36165 structure
    GC36165Glycyrrhisoflavone
    CAS: 116709-70-7
    纯度: >98.00%

    Glycyrrhisoflavone，一种活性异戊二烯类黄酮化合物，主要来源于 Glycyrrhiza uralensis Fisch. 的根部提取物。Glycyrrhisoflavone 抑制 α-葡萄糖苷酶 (α-glucosidase)。

  • GC36347 structure
    GC36347Isotanshinone I
    CAS: 20958-17-2

    Isotanshinone I 能够抑制α-葡萄糖苷酶 (α-glucosidase) 和糖基化终产物 (AGE)，其对 α-glucosidase 和 AGE 的 IC50 值分别为 1.13, 0.432 μM。

  • GC36375 structure
    GC36375Kaempferol 3-O-gentiobioside
    CAS: 22149-35-5
    纯度: >99.50%

    Kaempferol 3-O-gentiobioside 是一种从 C. alata 叶中分离得到的黄酮类化合物，具有抗糖尿病活性。Kaempferol 3-O-gentiobioside 有抗 α-glucosidase 活性，并具有对碳水化合物酶的抑制作用，其 IC50 值为 50.0 ?M。

  • GC38046 structure
    GC38046Gitogenin
    CAS: 511-96-6
    纯度: >99.50%

    A sapogenin with enzyme inhibitory and hormone-releasing activities

  • GC38279 structure
    GC38279Cedryl acetate
    CAS: 77-54-3
    纯度: >95.00%

    Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.

  • GC38995 structure
    GC38995Panasenoside
    CAS: 31512-06-8

    Panasenoside 是一种从 Lilium pumilum D. C 分离的类黄酮。 Panasenoside 具有 α-葡萄糖苷酶 (α-glucosidase) 抑制活性。

  • GC39233 structure
    GC39233Butyl isobutyl phthalate
    CAS: 17851-53-5
    纯度: >97.00%

    Butyl isobutyl phthalate (BIP), isolated from the rhizoid of Laminaria japonica, is a non-competitive inhibitor of α-glucosidase with IC50 of 38 μM. Butyl isobutyl phthalate displays a significant hypoglycemic effect and has the potential for diabetes treatment.

  • GC39795 structure
    GC39795(+)-Afzelechin
    CAS: 2545-00-8
    纯度: >98.00%

    (+)-Afzelechin 是从佛手根的根茎中分离出来的，是一种 α-葡萄糖苷酶 (alpha-glucosidase) 活性抑制剂，ID50 值为 0.13 mM。(+)-Afzelechin 可以延迟食物中碳水化合物的吸收，从而抑制餐后高血糖和高胰岛素血症。

  • GC41992 structure
    GC419921-Deoxynojirimycin (hydrochloride)
    CAS: 73285-50-4
    纯度: >98.00%

    An iminosugar with diverse biological activities

  • GC60706 structure
    GC60706Chrysophanol triglucoside
    CAS: 120181-07-9

    Chrysophanoltriglucoside是一种从决明子中分离出的蒽醌类化合物，可抑制蛋白酪氨酸磷酸酶1B(PTP1B)和α-glucosidase，IC50值分别为80.17和197.06µM。Chrysophanoltriglucoside具有糖尿病研究的潜力。

  • GC60802 structure
    GC60802Eleutherol
    CAS: 480-00-2

    Eleutherol是从E.americana中分离得到的萘类化合物，具有抗真菌(antifungal)活性。Eleutherol抑制白假丝酵母菌，白色念珠菌，酿酒酵母和新型隐球菌的MIC值在7.8-250µg/mL之间。Eleutherol具有α-葡萄糖苷酶(α-glucosidase)抑制活性，IC50>1.00mM。

  • GC61242 structure
    GC61242Resveratroloside
    CAS: 38963-95-0

    Resveratroloside是一种α-glucosidase的竞争新抑制剂，能调节血糖水平。Resveratroloside具有心脏保护作用。

  • GC61635 structure
    GC61635Kaempferol-7-O-rhamnoside
    CAS: 20196-89-8
    纯度: >98.00%

    Kaempferol-7-O-rhamnoside是从ChimonanthusnitensOliv叶子中分离的，一种有效的α-葡萄糖苷酶活性抑制剂。Kaempferol-7-O-rhamnoside有用于糖尿病的潜力。

  • GC61697 structure
    GC61697Naringinase
    CAS: 9068-31-9
    纯度: >98.00%

    Naringinase是一种水解酶复合物，具有α-L-鼠李糖苷酶和β-D-葡萄糖苷酶的活性。Naringinase在自然界中广泛存在。Naringinase可用于类固醇，抗生素的生物转化，主要用于糖苷的水解。

  • GC62551 structure
    GC62551β-Hydroxypropiovanillone
    CAS: 2196-18-1
    纯度: >98.00%

    β-Hydroxypropiovanillone 是一种天然化合物，对 α-葡萄糖苷酶 (α-glucosidase) 具有明显的浓度依赖性抑制作用 (IC50=257.8 μg/mL)。