GlpBio

Potassium Channel

Potassium Channel(钾离子通道)

Potassium channels are voltage-gated ion channels that selectively permeate potassium ion through the excitable membrane. It regulates the release of neurotransmitters, insulin secretion, smooth muscle contraction and heart rate etc.

Potassium Channel 相关产品(302)

  • GC16690 structure
    GC16690Y-27152
    CAS: 127408-30-4

    Y-27152 是 KATP (Kir6) 通道开放剂 Y-26763 的前药，是一种长效的 K+ 通道开放剂，具有较少的心动过速:对清醒状态的高血压大鼠和狗的抗高血压作用。

  • GC16717 structure
    GC167171-EBIO
    CAS: 10045-45-1
    纯度: >99.50%

    An activator of KCa channels

  • GC16848 structure
    GC16848P1075
    CAS: 60559-98-0
    纯度: >97.00%

    P1075是一种有效的、磺酰脲受体2相关的ATP敏感性的钾通道（SUR2-K IR 6） 的激活剂，EC 50 值为45±10nM。

  • GC16945 structure
    GC16945Astemizole
    CAS: 68844-77-9
    纯度: >99.50%

    Astemizole是一种强效抗组胺化合物，可拮抗组胺H1受体，IC 50 值为4nM。

  • GC16948 structure
    GC16948Valinomycin
    CAS: 2001-95-8
    纯度: >98.00% / >95.00%

    缬霉素Valinomycin是一种十二肽抗生素,从几种链霉菌菌株中获得。

  • GC17001 structure
    GC17001Verruculogen
    CAS: 12771-72-1
    纯度: >95.00%

    A tremorgenic mycotoxin

  • GC17264 structure
    GC17264ZM 226600
    CAS: 147695-92-9

    Kir6 (KATP) channel opener

  • GC17272 structure
    GC17272Charybdotoxin
    CAS: 95751-30-7

    A blocker of K+ channels

  • GC17280 structure
    GC17280NS 5806
    CAS: 426834-69-7
    纯度: >98.00%

    An I to current activator

  • GC17518 structure
    GC17518YS-035 hydrochloride
    CAS: 89805-39-0

    A calcium channel blocker

  • GC17595 structure
    GC17595CP 339818 hydrochloride
    CAS: 478341-55-8

    KV1.3 channel antagonist

  • GC17661 structure
    GC17661E-4031 dihydrochloride
    CAS: 113559-13-0
    纯度: >98.50%

    An antiarrhythmic, ERG potassium channel blocker

  • GC17739 structure
    GC17739PNU 37883 hydrochloride
    CAS: 57568-80-6

    PNU 37883 hydrochloride (PNU 37883A) 是一种选择性血管 ATP 敏感性钾 (Kir6, KATP) 通道阻滞剂。

  • GC17787 structure
    GC17787UK 78282 hydrochloride
    CAS: 136647-02-4

    KV1.3 and KV1.4 voltage-gated potassium channel blocker

  • GC17909 structure
    GC17909NS 6180
    CAS: 353262-04-1
    纯度: >99.50%

    An inhibitor of IKCa1/K Ca 3.1 channels

  • GC18203 structure
    GC18203Annonacin
    CAS: 111035-65-5
    纯度: >98.00%

    A mitochondrial complex I inhibitor

  • GC18210 structure
    GC18210GAL-021
    CAS: 1380341-99-0
    纯度: >98.00%

    A BK Ca channel blocker

  • GC18629 structure
    GC18629VU0071063
    CAS: 333415-38-6
    纯度: >99.00%

    A K ir 6.2/SUR1 activator

  • GC19004 structure
    GC19004SKA-121
    CAS: 1820708-73-3
    纯度: >99.00%

    A positive-gating modulator of IKCa1/K Ca 3.1 channels

  • GC19183 structure
    GC19183GSK369796 Dihydrochloride
    CAS: 1010411-21-8
    纯度: >98.00%

    An antimalarial agent

  • GC19480 structure
    GC19480AUT1
    CAS: 1311136-84-1
    纯度: >99.50%

    A positive modulator of K v 3.1b, K v 3.2a, and K v 3.3

  • GC30267 structure
    GC30267Pinacidil monohydrate
    CAS: 85371-64-8
    纯度: >99.00% / >98.00%

    Pinacidil monohydrate一种抗高血压药物，属于钾通道开放剂，通过激活ATP敏感性钾通道使血管平滑肌松弛。

  • GC30280 structure
    GC30280Chlorpromazine D6 hydrochloride
    CAS: 1228182-46-4
    纯度: >99.50%

    Chlorpromazine D6 hydrochloride是 Chlorpromazine 的氘代物，可被用于 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。

  • GC30891 structure
    GC30891Almitrine mesylate (Almitrine bismesylate)
    CAS: 29608-49-9
    纯度: >98.00%

    Almitrine mesylate (Almitrine bismesylate, Almitrine dimethanesulfonate, Almitrine dimesylate), a pharmacologically unique respiratory stimulant, acts as an agonist of peripheral chemoreceptors located on the carotid bodies. Almitrine mesylate inhibits the activity of Ca2+-dependent K+ channel by decreasing its open probability with IC50 of 0.22 μM.