GlpBio

Potassium Channel

Potassium Channel(钾离子通道)

Potassium channels are voltage-gated ion channels that selectively permeate potassium ion through the excitable membrane. It regulates the release of neurotransmitters, insulin secretion, smooth muscle contraction and heart rate etc.

Potassium Channel 相关产品(302)

  • GC12547 structure
    GC12547NS 1619
    CAS: 153587-01-0
    纯度: >98.00%

    NS 1619是一种选择性的大电导钙激活钾通道激活剂。

  • GC12575 structure
    GC12575DPO-1
    CAS: 43077-30-1

    An inhibitor of K v 1.5 channels

  • GC13188 structure
    GC13188UCL 2077
    CAS: 918311-87-2

    UCL 2077 是一种选择性慢后超极化 (sAHP) 通道阻滞剂（在培养的海马神经元中 IC50 =500 nM），对超极化后的 Ca2+ 通道、动作电位、输入电阻和介质影响最小。

  • GC13323 structure
    GC13323BDS I

    Kv3.4 potassium channel blocker, potent and reversible

  • GC13353 structure
    GC13353Spadin
    CAS: 1270083-24-3
    纯度: >99.00%

    An inhibitor of K 2P 2.1/TREK1

  • GC13455 structure
    GC13455VU 591 hydrochloride
    CAS: 1315380-70-1
    纯度: >98.00%

    VU 591 hydrochloride 是一种有效的、选择性的肾外髓质钾通道 (ROMK 或 Kir1.1) 抑制剂，IC50 为 0.24 μM。

  • GC13466 structure
    GC13466Flufenamic acid
    CAS: 530-78-9
    纯度: >99.50%

    An NSAID and COX inhibitor

  • GC13490 structure
    GC13490E-4031
    CAS: 113558-89-7
    纯度: >99.00%

    An antiarrhythmic, ERG potassium channel blocker

  • GC13819 structure
    GC13819Tertiapin LQ

    Kir1.1 channel blocker

  • GC13976 structure
    GC13976Doxapram hydrochloride hydrate
    CAS: 7081-53-0
    纯度: >99.50%

    A central respiratory stimulant

  • GC14029 structure
    GC14029Retigabine
    CAS: 150812-12-7

    Retigabine是一种抗惊厥化合物，可激活低阈值电压门控钾通道。

  • GC14044 structure
    GC14044(-)-[3R,4S]-Chromanol 293B
    CAS: 163163-24-4

    (-)-[3R,4S]-Chromanol 293B 是延迟整流器 K+ 电流 (IKs) 的慢速成分的有效选择性抑制剂。

  • GC14073 structure
    GC14073DCPIB
    CAS: 82749-70-0
    纯度: >99.50%

    A VRAC inhibitor

  • GC14113 structure
    GC14113Oxybutynin
    CAS: 5633-20-5
    纯度: >99.50%

    An antagonist of muscarinic acetylcholine receptors

  • GC14116 structure
    GC14116Cromakalim
    CAS: 94470-67-4

    A prototypical KATP channel activator

  • GC14216 structure
    GC14216Chlorpromazine HCl
    CAS: 69-09-0
    纯度: >99.50%

    Chlorpromazine HCl是一种口服有效的、可透过血脑屏障的吩噻嗪类抗精神病药，能够有效抑制D2多巴胺受体和5-HT 2A ，具有很强的镇静作用。

  • GC14239 structure
    GC14239BMS 191011
    CAS: 202821-81-6
    纯度: >98.50%

    A K Ca 1.1/BK channel activator

  • GC14297 structure
    GC14297ShK-Dap22
    CAS: 220384-25-8

    Extremely potent KV1.3 channel blocker

  • GC14515 structure
    GC14515Azimilide
    CAS: 149908-53-2

    A class III antiarrhythmic agent

  • GC14563 structure
    GC14563Ketanserin
    CAS: 74050-98-9
    纯度: >99.00% / >97.00%

    A potent 5-HT 2 receptor antagonist

  • GC14646 structure
    GC14646RuBi-4AP
    CAS: 851956-02-0

    voltage-dependent K+ channel blocker

  • GC14703 structure
    GC14703Oxybutynin chloride
    CAS: 1508-65-2
    纯度: >98.00%

    An antagonist of muscarinic acetylcholine receptors

  • GC14705 structure
    GC14705Tolbutamide Sodium
    CAS: 473-41-6
    纯度: >98.00%

    A SUR1/K ir 6.2 channel inhibitor

  • GC14754 structure
    GC14754Linopirdine dihydrochloride
    CAS: 113168-57-3

    A neurotransmitter release enhancer