Reactive Oxygen Species
Reactive Oxygen Species(活性氧)
Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.
ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Reactive Oxygen Species 相关产品(453)
- GC19765NorbergeninCAS: 79595-97-4纯度: >98.00%
Norbergenin 是 bergenin 的 O-去甲基衍生物，具有中等的抗氧化活性（在 DPPH 自由基清除中 IC50 为 13 μM；在超氧阴离子清除中为 32 μM）。
- GC20007Ginsenoside CKCAS: 39262-14-1纯度: >98.00%
Ginsenoside CK，一种由主要人参皂苷化合物转化而来的次级人参皂苷，比其母体人参皂苷具有更高的生物利用度和溶解性，具有极其重要的意义。
- GC200955,7-Dihydroxy-4-methylcoumarinCAS: 2107-76-8
A synthetic coumarin with diverse biological activities
- GC30033Sinapine thiocyanateCAS: 7431-77-8纯度: >99.00%
Sinapine thiocyanate is the thiocyanate salt form of Sinapine, which shows favorable biological activities such as antioxidant and radio-protective activities.
- GC30046Methoxy-PMS (1-Methoxy PMS)CAS: 65162-13-2纯度: >98.00% / >99.00% / >97.00%
Methoxy-PMS (1-Methoxy PMS)是一种合成电子传递体，广泛用于脱氢酶活性检测等生化分析。其作为氧化还原介体，促进NAD(P)H与四唑盐之间的电子转移以生成可检测的甲臜产物。Methoxy-PMS（C₁₄H₁₃N₂O₄S）是吩嗪硫酸甲酯（PMS）的甲氧基修饰衍生物，其吩嗪环上的甲氧基显著提升了稳定性和溶解度，增强了光稳定性及水溶性，使其适用于长时间酶反应、高通量筛选以及体外实验中的高效氧化还原循环。
- GC30067Butylhydroxyanisole (Butylated hydroxyanisole)CAS: 25013-16-5纯度: >99.00%
丁基羟基茴香醚（Butylated hydroxyanisole）（Butylated hydroxyanisole）是一种抗氧化剂，用作食品添加剂防腐剂。
- GC30263Glucosamine (D-Glucosamine)CAS: 3416-24-8纯度: >98.00%
Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.
- GC30416Mitoquinone (MitoQ)CAS: 444890-41-9纯度: >98.00%
Mitoquinone (MitoQ) 是一种泛醌衍生的抗氧化剂，可以共价连接到亲脂性三苯基膦 (TPP) 阳离子上，专门针对线粒体。
- GC30495Canthaxanthin (E 161g)CAS: 514-78-3纯度: >99.00%
Canthaxanthin (E 161g)是一种橙红色的类胡萝卜素，具有抗氧化、抗肿瘤等多种生物活性。
- GC31272Isosteviol ((-)-Isosteviol)CAS: 27975-19-5纯度: >98.00%
Isosteviol (ISV) is mainly obtained by acid hydrolysis of stevioside, the sweet food additive extracted from the plant Stevia Rebaudiana Bertoni (Bertoni). It possesses various biological activities including anti-hyperglycemic, anti-hypertensive, anti-tumor, anti-inflammatory, and antioxidant effects.
- GC312903-Indolepropionic acidCAS: 830-96-6纯度: >99.50%
A bacterial metabolite with antioxidant and neuroprotective activities
- GC31292Mitoquinone mesylate (Mitoquinone methanesulfonate)CAS: 845959-50-4纯度: >98.00%
Mitoquinone mesylate（Mitoquinone methanesulfonate）是广泛使用的靶向线粒体的抗氧化剂之一。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC19193 | HTHQ | 148081-72-5 | >99.50% | |
An antioxidant | ||||
| GC19377 | Visomitin | 934826-68-3 | >98.00% / >97.00% | |
A mitochondrial antioxidant | ||||
| GC19457 | Trolox | 53188-07-1 | >98.00% | |
Vitamin E derivative with antioxidant properties | ||||
| GC19496 | AAPH | 2997-92-4 | >99.00% | |
A water-soluble azo compound used as a free radical generator | ||||
| GC19759 | Mesotrione | 104206-82-8 | >98.00% | |
甲基磺草酮是一种除草剂，属于苯甲酰环己二酮家族。 | ||||
| GC19762 | Capsanthin (75%) | 465-42-9 | >75.00% | |
A carotenoid with diverse biological activities | ||||
| GC19765 | Norbergenin | 79595-97-4 | >98.00% | |
Norbergenin 是 bergenin 的 O-去甲基衍生物，具有中等的抗氧化活性（在 DPPH 自由基清除中 IC50 为 13 μM；在超氧阴离子清除中为 32 μM）。 | ||||
| GC19819 | Ermanin | 20869-95-8 | - | |
Ermanin 是一种从 Tanacetum microphyllum 中分离出来的类黄酮。 | ||||
| GC20007 | Ginsenoside CK | 39262-14-1 | >98.00% | |
Ginsenoside CK，一种由主要人参皂苷化合物转化而来的次级人参皂苷，比其母体人参皂苷具有更高的生物利用度和溶解性，具有极其重要的意义。 | ||||
| GC20091 | α-Arbutin | 84380-01-8 | >99.00% | |
A glycosylated hydroquinone with diverse biological activities | ||||
| GC20095 | 5,7-Dihydroxy-4-methylcoumarin | 2107-76-8 | - | |
A synthetic coumarin with diverse biological activities | ||||
| GC30006 | H2DCFDA (DCFH-DA) | 4091-99-0 | >97.00% | |
H2DCFDA（DCFH-DA）是一种氧化还原敏感的荧光探针，可用于测量细胞内活性氧水平。 | ||||
| GC30033 | Sinapine thiocyanate | 7431-77-8 | >99.00% | |
Sinapine thiocyanate is the thiocyanate salt form of Sinapine, which shows favorable biological activities such as antioxidant and radio-protective activities. | ||||
| GC30046 | Methoxy-PMS (1-Methoxy PMS) | 65162-13-2 | >98.00% / >99.00% / >97.00% | |
Methoxy-PMS (1-Methoxy PMS)是一种合成电子传递体，广泛用于脱氢酶活性检测等生化分析。其作为氧化还原介体，促进NAD(P)H与四唑盐之间的电子转移以生成可检测的甲臜产物。Methoxy-PMS（C₁₄H₁₃N₂O₄S）是吩嗪硫酸甲酯（PMS）的甲氧基修饰衍生物，其吩嗪环上的甲氧基显著提升了稳定性和溶解度，增强了光稳定性及水溶性，使其适用于长时间酶反应、高通量筛选以及体外实验中的高效氧化还原循环。 | ||||
| GC30067 | Butylhydroxyanisole (Butylated hydroxyanisole) | 25013-16-5 | >99.00% | |
丁基羟基茴香醚（Butylated hydroxyanisole）（Butylated hydroxyanisole）是一种抗氧化剂，用作食品添加剂防腐剂。 | ||||
| GC30080 | Phillygenin (Phillygenol) | 487-39-8 | >98.00% | |
A lignan with diverse biological activities | ||||
| GC30263 | Glucosamine (D-Glucosamine) | 3416-24-8 | >98.00% | |
Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites. | ||||
| GC30416 | Mitoquinone (MitoQ) | 444890-41-9 | >98.00% | |
Mitoquinone (MitoQ) 是一种泛醌衍生的抗氧化剂，可以共价连接到亲脂性三苯基膦 (TPP) 阳离子上，专门针对线粒体。 | ||||
| GC30495 | Canthaxanthin (E 161g) | 514-78-3 | >99.00% | |
Canthaxanthin (E 161g)是一种橙红色的类胡萝卜素，具有抗氧化、抗肿瘤等多种生物活性。 | ||||
| GC30500 | Melittoside | 19467-03-9 | >99.00% | |
An iridoid glycoside | ||||
| GC30532 | Sulcotrione | 99105-77-8 | >99.00% | |
Sulcotrione是β-三酮除草剂，可以抑制羟基苯基丙酮酸双加氧酶(HPPD)。 | ||||
| GC31272 | Isosteviol ((-)-Isosteviol) | 27975-19-5 | >98.00% | |
Isosteviol (ISV) is mainly obtained by acid hydrolysis of stevioside, the sweet food additive extracted from the plant Stevia Rebaudiana Bertoni (Bertoni). It possesses various biological activities including anti-hyperglycemic, anti-hypertensive, anti-tumor, anti-inflammatory, and antioxidant effects. | ||||
| GC31290 | 3-Indolepropionic acid | 830-96-6 | >99.50% | |
A bacterial metabolite with antioxidant and neuroprotective activities | ||||
| GC31292 | Mitoquinone mesylate (Mitoquinone methanesulfonate) | 845959-50-4 | >98.00% | |
Mitoquinone mesylate（Mitoquinone methanesulfonate）是广泛使用的靶向线粒体的抗氧化剂之一。 | ||||