5-HT Receptor
5-HT Receptor(5-羟色胺受体)
5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.
5-HT Receptor 相关产品(481)
- GC15829Urapidil HClCAS: 64887-14-5纯度: >99.00%
An α 1 -AR antagonist and 5-HT 1A receptor partial agonist
- GC16029Granisetron HClCAS: 107007-99-8纯度: >99.50%
A 5-HT 3 receptor antagonist with antiemetic activity
- GC16312VortioxetineCAS: 508233-74-7纯度: >99.50%
Vortioxetine是一种多模式抗抑郁药，对重组人5-HT1A（K i =15nM）、5-HT1B（K i =33nM）、5-HT3A（K i =3.7nM）、5-HT7（K i =19nM）、noradrenergic β1 receptor（K i =46nM）以及SERT（K i =1.6nM）具有高亲和力。
- GC17981AgomelatineCAS: 138112-76-2纯度: >98.50%
Agomelatine是一种褪黑素（MT）受体激动剂，对MT1和MT2的K i 值分别为0.1 nM和0.12 nM。Agomelatine也是一种5-羟色胺（5-HT）受体拮抗剂，对5-HT 2C 和5-HT 2B 的K i 值分别为631 nM和660 nM。
- GC18006Sumatriptan SuccinateCAS: 103628-48-4纯度: >99.50%
Sumatriptan Succinate是一种具有口服活性的5-HT1受体激动剂，对5-HT1D、5-HT1B和5-HT1F受体的IC 50 值分别为7.3nM、9.3nM和17.8nM。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC15121 | Lasmiditan | 439239-90-4 | - | |
An Analytical Reference Standard | ||||
| GC15153 | Almotriptan Malate | 181183-52-8 | >98.00% | |
An agonist of 5-HT 1B and 5-HT 1D receptors | ||||
| GC15223 | Tropisetron Hydrochloride | 105826-92-4 | >99.50% | |
A 5-HT 3 receptor antagonist | ||||
| GC15463 | Iloperidone | 133454-47-4 | >99.50% | |
An atypical antipsychotic | ||||
| GC15687 | Azasetron HCl | 123040-16-4 | >98.00% | |
A 5-HT 3 receptor antagonist | ||||
| GC15754 | WAY-100635 Maleate | 1092679-51-0 | >99.00% | |
A serotonin 5-HT 1A antagonist | ||||
| GC15829 | Urapidil HCl | 64887-14-5 | >99.00% | |
An α 1 -AR antagonist and 5-HT 1A receptor partial agonist | ||||
| GC16017 | Rotigotine hydrochloride | 125572-93-2 | >99.00% | |
A non-selective dopamine receptor agonist | ||||
| GC16029 | Granisetron HCl | 107007-99-8 | >99.50% | |
A 5-HT 3 receptor antagonist with antiemetic activity | ||||
| GC16142 | Ondansetron | 99614-02-5 | >99.00% | |
A Certified Reference Material | ||||
| GC16226 | BRL-15572 dihydrochloride | 193611-72-2 | >99.00% | |
A 5-HT 1D receptor antagonist | ||||
| GC16270 | WAY-100635 maleate salt | 634908-75-1 | >98.00% | |
A serotonin 5-HT 1A antagonist | ||||
| GC16312 | Vortioxetine | 508233-74-7 | >99.50% | |
Vortioxetine是一种多模式抗抑郁药，对重组人5-HT1A（K i =15nM）、5-HT1B（K i =33nM）、5-HT3A（K i =3.7nM）、5-HT7（K i =19nM）、noradrenergic β1 receptor（K i =46nM）以及SERT（K i =1.6nM）具有高亲和力。 | ||||
| GC16788 | PRX-08066 Maleic acid | 866206-55-5 | - | |
5-HT2B receptor antagonist,potent and selective | ||||
| GC17053 | Eletriptan HBr | 177834-92-3 | >98.00% | |
An agonist of 5-HT 1B and 5-HT 1D receptors | ||||
| GC17061 | Dapoxetine HCl | 129938-20-1 | >99.50% | |
An Analytical Reference Standard | ||||
| GC17130 | BRL-54443 | 57477-39-1 | >99.00% | |
A potent agonist of 5-HT 1E and 5-HT 1F | ||||
| GC17138 | LY310762 | 192927-92-7 | >98.00% | |
A 5-HT 1D antagonist | ||||
| GC17536 | Mosapride Citrate | 112885-42-4 | >98.00% | |
A 5-HT 4 receptor agonist | ||||
| GC17593 | Lurasidone HCl | 367514-88-3 | >98.00% | |
An atypical antipsychotic | ||||
| GC17808 | Zolmitriptan | 139264-17-8 | >99.50% / >98.00% | |
An agonist of 5-HT 1B and 5-HT 1D receptors | ||||
| GC17917 | Palonosetron HCl | 135729-62-3 | >99.50% | |
A 5-HT 3 receptor antagonist | ||||
| GC17981 | Agomelatine | 138112-76-2 | >98.50% | |
Agomelatine是一种褪黑素（MT）受体激动剂，对MT1和MT2的K i 值分别为0.1 nM和0.12 nM。Agomelatine也是一种5-羟色胺（5-HT）受体拮抗剂，对5-HT 2C 和5-HT 2B 的K i 值分别为631 nM和660 nM。 | ||||
| GC18006 | Sumatriptan Succinate | 103628-48-4 | >99.50% | |
Sumatriptan Succinate是一种具有口服活性的5-HT1受体激动剂，对5-HT1D、5-HT1B和5-HT1F受体的IC 50 值分别为7.3nM、9.3nM和17.8nM。 | ||||