Histamine Receptor
Histamine Receptor(组胺受体)
Histamine receptor has 4 subtypes (H1,H2,H3 and H4) which mediates various biological fuctions, including allergic reaction, gastric acid secretion and inflammation etc.
Histamine Receptor 相关产品(236)
- GC38558PF-03654746 TosylateCAS: 1039399-17-1纯度: >99.50%
PF-03654746 Tosylate (PF-03654746) 是一种有效的选择性组胺 H3 receptor 拮抗剂，具有脑渗透性。PF-03654746 Tosylate (PF-03654746) 可减少过敏原引起的鼻炎反应。PF-03654746 Tosylate (PF-03654746) 用于治疗人类认知障碍，改善阿尔茨海默病人 (AD) 的认知。
- GC39479BepotastineCAS: 125602-71-3纯度: >98.00%
Bepotastine是一种非镇静的、具有口服活性的第二代组胺H1受体（histamine H1 receptor）拮抗剂，其作用选择性高于H3受体、α1、α2和β肾上腺素能受体、多巴胺D2受体、血清素5-HT2受体、乙酰胆碱迷走神经受体以及苯二氮䓬受体。
- GC39735Triprolidine hydrochloride monohydrateCAS: 6138-79-0纯度: >99.50%
Triprolidine Hydrochloride is the hydrochloride salt form of Triprolidine, which is the first generation histamine H1 antagonist used in allergic rhinitis.
- GC41715(R)-Cetirizine (hydrochloride)CAS: 130018-87-0纯度: >99.50%
A selective histamine H 1 receptor antagonist
- GC43353Cyproheptadine (hydrochloride hydrate)CAS: 41354-29-4纯度: >99.00%
An antihistamine with antiserotonergic and anticholinergic activities
- GC60072BetahistineCAS: 5638-76-6纯度: >98.00%
A histamine H 3 receptor antagonist and histamine H 1 receptor agonist
- GC60563Acrivastine D7CAS: 172165-56-9
AcrivastineD7(BW825CD7)是Acrivastine的一种氘代化合物。Acrivastine是一种短效的histamine1受体拮抗剂。
- GC60641Betahistine mesylateCAS: 54856-23-4纯度: >98.00%
Betahistine mesylate is the mesylate salt form of Betahistine, a histamine analog and H3 receptor agonist that serves as a vasodilator.
- GC60691Cetirizine Impurity CCAS: 83881-59-8
CetirizineImpurityC是Cetirizine的一种杂质。Cetirizine是羟嗪的羧化代谢物，是第二代抗组胺剂。Cetirizine是一种特异的、具有口服活性的H1受体(histamineH1-receptor)的长效拮抗剂。
- GC60791Doxepin D3 HydrochlorideCAS: 347840-07-7
DoxepinD3Hydrochloride是DoxepinHydrochloride的氘代物。Doxepinhydrochloride是一种口服活性的三环抗抑郁药。Doxepinhydrochloride是一种有效的选择性组胺受体H1拮抗剂。Doxepinhydrochloride也是一种有效的CYP450抑制剂，并显着抑制CYP4502C19和CYP4501A2。
- GC61256Rupatadine D4 fumarateCAS: 1795153-63-7
RupatadineD4fumarate(UR-12592D4fumarate)是Rupatadinefumarate的氘代标记物。RupatadineFumarate(UR-12592Fumarate)富马酸盐是PAF/H1受体双抑制剂，Ki值分别为0.55μM和0.1μM。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC37959 | Zaltidine | 85604-00-8 | >99.00% | |
Zaltidine(CP-57361)是H2受体拮抗剂，有抗分泌活性。 | ||||
| GC38450 | LML134 | 1542135-76-1 | >99.50% | |
LML134 (化合物 18b) 是一种具有口服活性，高选择性 H3R (组胺 3 受体) 反向激动剂，对 hH3R 的 cAMP 和 bdg 的 Kis 分别为 0.3 nM 和 12 nM。LML134 快速穿透大脑，导致高 H3R 占有率，并以快速的动力学特征使其目标脱离。LML134 用于治疗过度睡眠障碍。 | ||||
| GC38558 | PF-03654746 Tosylate | 1039399-17-1 | >99.50% | |
PF-03654746 Tosylate (PF-03654746) 是一种有效的选择性组胺 H3 receptor 拮抗剂，具有脑渗透性。PF-03654746 Tosylate (PF-03654746) 可减少过敏原引起的鼻炎反应。PF-03654746 Tosylate (PF-03654746) 用于治疗人类认知障碍，改善阿尔茨海默病人 (AD) 的认知。 | ||||
| GC39378 | Emedastine | 87233-61-2 | >98.00% | |
A histamine H 1 receptor antagonist | ||||
| GC39479 | Bepotastine | 125602-71-3 | >98.00% | |
Bepotastine是一种非镇静的、具有口服活性的第二代组胺H1受体（histamine H1 receptor）拮抗剂，其作用选择性高于H3受体、α1、α2和β肾上腺素能受体、多巴胺D2受体、血清素5-HT2受体、乙酰胆碱迷走神经受体以及苯二氮䓬受体。 | ||||
| GC39735 | Triprolidine hydrochloride monohydrate | 6138-79-0 | >99.50% | |
Triprolidine Hydrochloride is the hydrochloride salt form of Triprolidine, which is the first generation histamine H1 antagonist used in allergic rhinitis. | ||||
| GC41715 | (R)-Cetirizine (hydrochloride) | 130018-87-0 | >99.50% | |
A selective histamine H 1 receptor antagonist | ||||
| GC43353 | Cyproheptadine (hydrochloride hydrate) | 41354-29-4 | >99.00% | |
An antihistamine with antiserotonergic and anticholinergic activities | ||||
| GC43427 | Dexchlorpheniramine (maleate) | 2438-32-6 | >98.00% | |
A histamine H 1 receptor antagonist | ||||
| GC43598 | Emedastine (fumarate) | 87233-62-3 | >98.00% | |
A histamine H 1 receptor antagonist | ||||
| GC44360 | Nedocromil (sodium salt) | 69049-74-7 | >98.00% | |
A mast cell stabilizer | ||||
| GC46185 | Nimbin | 5945-86-8 | >98.00% | |
A limonoid with diverse biological activities | ||||
| GC48835 | Diphenylpyraline | 147-20-6 | >95.00% | |
A histamine H 1 receptor antagonist | ||||
| GC48892 | NSC 19005 | 5452-87-9 | >95.00% | |
A potential impurity found in commercial preparations of betahistine | ||||
| GC50405 | JNJ 39758979 dihydrochloride | - | - | |
高亲和力和选择性组胺H4拮抗剂；口服生物利用度 | ||||
| GC60072 | Betahistine | 5638-76-6 | >98.00% | |
A histamine H 3 receptor antagonist and histamine H 1 receptor agonist | ||||
| GC60563 | Acrivastine D7 | 172165-56-9 | - | |
AcrivastineD7(BW825CD7)是Acrivastine的一种氘代化合物。Acrivastine是一种短效的histamine1受体拮抗剂。 | ||||
| GC60641 | Betahistine mesylate | 54856-23-4 | >98.00% | |
Betahistine mesylate is the mesylate salt form of Betahistine, a histamine analog and H3 receptor agonist that serves as a vasodilator. | ||||
| GC60691 | Cetirizine Impurity C | 83881-59-8 | - | |
CetirizineImpurityC是Cetirizine的一种杂质。Cetirizine是羟嗪的羧化代谢物，是第二代抗组胺剂。Cetirizine是一种特异的、具有口服活性的H1受体(histamineH1-receptor)的长效拮抗剂。 | ||||
| GC60709 | Cinnarizine D8 | 1185242-27-6 | - | |
An internal standard for the quantification of cinnarizine | ||||
| GC60791 | Doxepin D3 Hydrochloride | 347840-07-7 | - | |
DoxepinD3Hydrochloride是DoxepinHydrochloride的氘代物。Doxepinhydrochloride是一种口服活性的三环抗抑郁药。Doxepinhydrochloride是一种有效的选择性组胺受体H1拮抗剂。Doxepinhydrochloride也是一种有效的CYP450抑制剂，并显着抑制CYP4502C19和CYP4501A2。 | ||||
| GC60924 | Hydroxyzine D8 | 1189480-47-4 | - | |
An internal standard for the quantification of hydroxyzine | ||||
| GC61256 | Rupatadine D4 fumarate | 1795153-63-7 | - | |
RupatadineD4fumarate(UR-12592D4fumarate)是Rupatadinefumarate的氘代标记物。RupatadineFumarate(UR-12592Fumarate)富马酸盐是PAF/H1受体双抑制剂，Ki值分别为0.55μM和0.1μM。 | ||||
| GC61401 | Oxatomide | 60607-34-3 | >99.00% | |
Oxatomide是一种口服活性的H1受体拮抗剂（抗组胺药）。 | ||||