GlpBio

Histamine Receptor

Histamine Receptor(组胺受体)

Histamine receptor has 4 subtypes (H1,H2,H3 and H4) which mediates various biological fuctions, including allergic reaction, gastric acid secretion and inflammation etc.

Histamine Receptor 相关产品(236)

  • GC31897 structure
    GC31897Pirolate (CP-32387)
    CAS: 55149-05-8

    Pirolate (CP-32387) 是一种组胺 H1 受体拮抗剂。

  • GC31994 structure
    GC31994CI-949
    CAS: 104961-19-5

    CI-949是一种过敏介质释放抑制剂，可抑制组胺(histamine)，白三烯C4/D4(LTC4/LTD4)和血栓素B2(TXB2)的释放，IC50分别为11.4μM，0.5μM和0.1μM。

  • GC32001 structure
    GC32001KP136 (AL136)
    CAS: 76239-32-2

    KP136 (AL136) (AL136) 是一种口服有效的抗过敏剂。

  • GC32050 structure
    GC32050FRG8701
    CAS: 108498-50-6

    FRG-8701是一种新组氨酸H2-receptor拮抗剂，IC50值为0.25至0.43μM。

  • GC32979 structure
    GC32979Chloropyramine hydrochloride
    CAS: 6170-42-9
    纯度: >99.50%

    Chloropyramine hydrochloride (Halopyramine) is a histamine receptor H1 antagonist and has anti-cholinergic, antispasmodic, and antiallergic effects.

  • GC33499 structure
    GC33499Fexofenadine D6 (MDL-16455 D6)
    CAS: 548783-71-7
    纯度: >99.00%

    Fexofenadine D6 (MDL-16455 D6) 被氘标记为 Fexofenadine，它是一种抗组胺药。

  • GC33544 structure
    GC33544(±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6)
    CAS: 1189805-51-3
    纯度: >98.00%

    (±)-Levomepromazine D6 ((±)-Methotrimeprazine D6) 是氘标记的 Methotrimeprazine，它是一种 D3 多巴胺和组胺 H1 受体拮抗剂。

  • GC33879 structure
    GC33879Azelastine
    CAS: 58581-89-8
    纯度: >98.00%

    Azelastine HCl is a potent, second-generation, selective, histamine receptor antagonist, used in the treatment of rhinitis.

  • GC34338 structure
    GC34338H3R-IN-1 Hydrochloride

    H3R-IN-1Hydrochloride是一种有效的组胺受体3(H3R)反向激动剂，详细信息请参考专利文献WO2013107336A1中的化合物2。

  • GC35222 structure
    GC35222ABT-239
    CAS: 460746-46-7
    纯度: >99.00%

    ABT-239 是一种新颖的，高效的，非咪唑类的 H3R 拮抗剂，也是 TRPV1 的拮抗剂。

  • GC35284 structure
    GC35284Alimemazine D6
    CAS: 1346603-88-0

    Alimemazine D6是Alimemazine氘代化合物标准品。

  • GC35471 structure
    GC35471Bavisant
    CAS: 929622-08-2

    Bavisant (JNJ-31001074)是口服活性人H3受体拮抗剂。

  • GC35472 structure
    GC35472Bavisant dihydrochloride
    CAS: 929622-09-3

    Bavisant盐酸盐(JNJ-31001074)是口服活性人H3受体拮抗剂。

  • GC35473 structure
    GC35473Bavisant dihydrochloride hydrate
    CAS: 1103522-80-0
    纯度: >99.50%

    Bavisant dihydrochloride hydrate (JNJ31001074AAC) 是口服活性人H3 受体拮抗剂。

  • GC35655 structure
    GC35655Cetirizine D4 dihydrochloride

    Cetirizine D4二盐酸盐是Cetirizine氘代化合物标准品。

  • GC35656 structure
    GC35656Cetirizine D8 dihydrochloride
    CAS: 2070015-04-0

    An internal standard for the quantification of cetirizine,(R)-cetirizine, and (S)-cetirizine

  • GC35826 structure
    GC35826Decloxizine dihydrochloride
    CAS: 13073-96-6
    纯度: >98.50%

    Decloxizine（UCB-1402; NSC289116）二盐酸盐1型组胺受体H1拮抗剂。

  • GC36278 structure
    GC36278Hydroxyzine D4 dihydrochloride

    Hydroxyzine D4二盐酸盐是Hydroxyzine氘代化合物标准品。

  • GC36279 structure
    GC36279Hydroxyzine pamoate
    CAS: 10246-75-0
    纯度: >99.50%

    Hydroxyzine Pamoate is the pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties.

  • GC36476 structure
    GC36476Lodoxamide tromethamine
    CAS: 63610-09-3
    纯度: >99.00%

    A potent agonist of GPR35 and a mast cell stabilizer

  • GC36875 structure
    GC36875Perphenazine D8 Dihydrochloride

    Perphenazine D8二盐酸盐是Perphenazine氘代化合物标准品。

  • GC36878 structure
    GC36878PF-03654746
    CAS: 935840-31-6

    PF-03654746 是一种有效的选择性 H3 histamine H3 receptor 受体拮抗剂，具有高脑渗透性。PF-03654746 可减少过敏原引起的鼻腔症状，可能是进一步探索过敏性鼻炎的新型治疗策略。PF-03654746 提高阿尔茨海默病 (AD) 的认知功效和改善疾病的效果。

  • GC36931 structure
    GC36931Pitolisant
    CAS: 362665-56-3

    A histamine H 3 receptor antagonist and inverse agonist

  • GC36932 structure
    GC36932Pitolisant oxalate
    CAS: 362665-57-4

    A histamine H 3 receptor antagonist and inverse agonist