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Home >> Signaling Pathways >> Apoptosis >> Other Apoptosis

Other Apoptosis(其他细胞凋亡)

  1. Cat.No. 产品名称 Information
  2. GC38165 Euphorbia Factor L1

    大戟因子L1

     Euphorbia factor L1, a diterpenoid isolated from Euphorbia lathyris, inhibits osteoclastogenesis and induces osteoclast apoptosis.
  3. GC38392 Euscaphic acid

    野鸦椿酸

     A triterpene with diverse biological activities
  4. GC14791 F16 A potential antitumor agent
  5. GC38437 Fangchinoline

    防己诺林碱

     An alkaloid with diverse biological activities
  6. GC14499 Fenoprofen calcium hydrate

    非诺洛芬钙盐二水合物,Fenoprofen calcium salt dihydrate

     An NSAID
  7. GC12940 Fidaxomicin

    非达霉素; OPT-80; PAR-101

     A natural antibiotic
  8. GC36046 Fimasartan

    非马沙坦; BR-A-657

     Fimasartan (Kanarb) is a non-peptide angiotensin II receptor antagonist (ARB) with noncompetitive, insurmountable binding with the AT1 receptor. It is used for the treatment of hypertension and heart failure.
  9. GC41261 Flavokawain B

    黄卡瓦胡椒素B,Flavokavain B

     Induces cancer cell apoptosis
  10. GC36050 Flavokawain C

    卡瓦胡椒素C

     Flavokawain C 是存在卡瓦胡椒根中的天然查尔酮。Flavokawain C 对多种人类癌症细胞系产生细胞毒性，对 HCT 116 细胞作用的 IC50 值为 12.75 μM。
  11. GC16875 FLLL32

    (2E,2'E)-1,1'-环己基亚基二[3-(3,4-二甲氧基苯基)-2-丙烯-1-酮]

     An inhibitor of JAK2/STAT3 signaling
  12. GC13210 Flubendazole

    氟苯咪唑

     An anthelmintic
  13. GC14144 Fludarabine

    氟达拉滨; F-ara-A; NSC 118218

     Fludarabine是一种抑制DNA合成的嘌呤类似物。
  14. GC15134 Fludarabine Phosphate (Fludara)

    磷酸氟达拉滨; NSC 118218 phosphate

     A prodrug form of fludarabine and 2-fluoro-ara-ATP
  15. GC16880 Flurbiprofen

    氟比洛芬; dl-Flurbiprofen

     A non-selective COX inhibitor
  16. GN10527 Formononetin

    刺芒柄花素: Biochanin B: Flavosil; Formononetol

     Formononetin是一种强效的FGFR2抑制剂，其IC50值约为4.31μM。Formononetin能有效抑制血管生成和肿瘤生长。
  17. GC36065 Formosanin C

    重楼皂苷B

     Polyphyllin B (Formosanin C, FC), a diosgenin saponin isolated from Paris formosana, is an immunomodulator with antitumor activity. Polyphyllin B (Formosanin C, FC) induces apoptosis.
  18. GC33029 Forodesine (BCX-1777 freebase)

    呋咯地辛; BCX-1777; Immucillin-H

     A nucleoside analog and PNP inhibitor
  19. GC32708 Forodesine hydrochloride (BCX-1777)

    BCX-1777 hydrochloride; Immucillin-H hydrochloride

     A nucleoside analog and PNP inhibitor
  20. GC12308 Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium

    CA 4DP; CA 4P; Combretastatin A4 disodium phosphate

     A potent inhibitor of tubulin polymerization
  21. GC25428 Foscenvivint (ICG-001) Foscenvivint (ICG-001) antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300. ICG-001 induces apoptosis.
  22. GC10647 FR 180204

    ERK Inhibitor II

     A potent, cell-permeable inhibitor of ERK1/2
  23. GC16310 FTI 277 HCl FTI 277 HCl 是法尼基转移酶 (FTase) 的抑制剂；一种高效的 Ras CAAX 肽模拟物，可拮抗 H-和 K-Ras 致癌信号传导。
  24. GC32138 Furazolidone

    呋喃唑酮

     A nitrofuran antiprotozoal and antibacterial agent
  25. GC12178 G-749

    G-749

     An FLT3 kinase inhibitor
  26. GC36103 Galanthamine hydrobromide Galanthamine氢溴酸盐是长效的中心活性的乙酰胆碱酯酶（AChE）抑制剂，IC50为410 nM，同时是神经元烟碱乙酰胆碱受体的变构增强剂。
  27. GN10388 Gallic acid

    没食子酸; 3,4,5-Trihydroxybenzoic acid

     A phenol with diverse biological activities
  28. GC17655 Ganetespib (STA-9090)

    STA9090, STA 9090

     Ganetespib (STA-9090) (STA-9090) 是一种热休克蛋白 90 (HSP90) 抑制剂，在多种血液和实体肿瘤细胞系中表现出强效细胞毒性。 Ganetespib (STA-9090) 通过抑制 HIF-1α 在结直肠癌中具有抗血管生成作用；和 STAT3。
  29. GC36114 Ganoderenic acid D

    灵芝烯酸D

     Ganoderenic acid D 是一种灵芝提取物 (GLE)，三萜。 Ganoderenic acid D 通过诱导细胞周期停滞和细胞凋亡 apoptosis 来抑制癌细胞的增殖。
  30. GN10109 Ganoderic Acid A

    灵芝酸 A

     A triterpene with diverse biological activities
  31. GC13474 Garcinol

    山竹子素

    Garcinol是组蛋白乙酰转移酶p300和PCAF的非特异性抑制剂，IC50分别为7μM和5μM。
  32. GC36122 Gardenin B

    栀子黄素B

     Gardenin B 是从 Baccharis scandens 中分离出的一种黄酮类化合物。Gardenin B 能诱导人白血病细胞死亡，诱导的凋亡发生与多个 caspases 相关。
  33. GC32710 GDC-0077 (RG6114)

    GDC-0077; RG6114

     Inavolisib (GDC-0077, RG6114, RO-7113755) is a potent selective inhibitor of PI3K alpha (PI3Kα) with an IC50 of 0.038 nM. GDC-0077 is >300-fold more selective for PI3K alpha over the other class I PI3K isoforms (beta, delta, and gamma) and >2000-fold more selective over PIK family members. GDC-0077 binds to the ATP binding site of PI3K and inhibits the phosphorylation of PIP2 to PIP3.
  34. GC14247 GDC-0623

    RG 7421; MEK inhibitor 1

     A potent, ATP-uncompetitive inhibitor of MEK1
  35. GC10816 GDC-0941

    GDC-0941

     A pan inhibitor of class I PI3K isoforms
  36. GC11177 GDC-0980 (RG7422)

    (S)-1-[4-[[2-(2-氨基嘧啶-5-基)-7-甲基-4-(吗啉-4-基)噻吩并[3,2-D]嘧啶-6-基]甲基]哌嗪-1-基]-2-羟基丙-1-酮,GDC-0980; GNE 390; RG 7422

     A dual inhibitor of PI3K and mTOR
  37. GC36130 Gemcitabine elaidate

    反油酸吉西他滨; CP-4126; CO-101; Gemcitabine 5'-elaidate

     A prodrug form of gemcitabine
  38. GN10076 Geniposidic acid

    京尼平苷酸

     An iridoid glycoside with diverse biological activities
  39. GC14102 Genistein

    染料木素; NPI 031L

     染料木黄酮是一种异黄酮，属于类黄酮化合物，存在于多种植物中。
  40. GC36132 Genistein 8-c-glucoside

    染料木素 8-C-葡萄糖苷; G8CG

     Genistein 8-c-glucoside (G8CG) 是从 Lupinus luteus L 花中分离的一种天然葡萄糖苷。Genistein 8-c-glucoside 诱导线粒体膜去极化并诱导细胞凋亡 (apoptosis)。
  41. GC40673 Geranyl Acetate

    乙酸香叶酯

     A monoterpene with diverse biological activities
  42. GC19164 GGTI298 Trifluoroacetate A geranylgeranyltransferase I inhibitor
  43. GN10453 Ginkgolide B

    银杏内酯 B; 白果苦内酯 B; BN-52021

     Ginkgolide B是从银杏叶中提取的一种萜内酯，是血小板活化因子（PAF）的特异性拮抗剂, IC50为 3.6μM。
  44. GN10148 Ginsenoside F2

    人参皂苷F2

     A ginsenoside with diverse biological activities
  45. GC36137 Ginsenoside F4

    人参皂苷F4

     Ginsenoside F4 (GF4)，人参皂甙，从三七或红参中分离。Ginsenoside F4 (GF4) 通过诱导凋亡 (apoptosis) 对人淋巴细胞瘤 JK 细胞具有抑制作用。Ginsenoside F4 (GF4) 抑制 IL-1β 处理的软骨细胞中基质金属蛋白酶 13 (MMP 13) 的表达，阻断兔软骨组织培养中的软骨损坏，具有防止病变组织的软骨胶原基质分解的治疗潜力。
  46. GN10544 Ginsenoside Rg1

    人参皂苷 Rg1; Panaxoside A; Panaxoside Rg1

     人参皂苷Rg1是人参的主要活性成分之一，是一种具有多种生物活性的甾体糖苷。人参皂苷Rg1可降低大脑Aβ 水平并减少 NF-κB 核转移。
  47. GN10019 Ginsenoside Rg6

    人参皂苷 Rg6

     Ginsenoside Rg6 抑制 TNF-α 诱导的 NF-κB 转录活性，在 HepG2 细胞中的 IC50 为 29.34 μM。
  48. GN10686 Ginsenoside Rh2

    人参皂苷 Rh2; 20(S)-Ginsenoside Rh2; 20(S)-Rh2; Ginsenoside-Rh2

     A natural steroid glycoside with diverse effects
  49. GC32998 Ginsenoside Rh4

    人参皂苷RH4

     Ginsenoside Rh4 is an important active ingredient of traditional Chinese medicine ginseng, which has been shown to inhibit Wnt/β-Catenin, JAK2/STAT3, TGF-β/Smad2/3 and other signaling pathways.
  50. GN10584 Ginsenoside Rk1

    人参皂苷

     人参皂甙 Rk1 是通过在高温下加工人参植物（主要是 Sung Ginseng，SG）而产生的独特成分 。
  51. GC38606 Glaucocalyxin A

    蓝萼甲素

     Glaucocalyxin A is a biologically active ent-kauranoid diterpenoid isolated from Rabdosia japonica var. glaucocalyx with antitumor and anti-inflammatory activity. Glaucocalyxin A induces G2/M cell cycle arrest and apoptosis through the PI3K/Akt pathway in human bladder cancer cells.

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