GlpBio

PF 750

目录号: GC15358纯度: >98.00%同义词: N-苯基-4-(3-喹啉基甲基)-1-哌啶甲酰胺
A selective, potent FAAH inhibitor
PF 750
Cas No.: 959151-50-9
规格价格库存数量操作
1mg¥277.00现货
1
5mg¥1,124.00现货
1
10mg¥1,987.00现货
1
25mg¥2,376.00现货
1
50mg¥8,516.00现货
1
10mM (in 1mL DMSO)¥762.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC50s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme’s active site serine nucleophile[1].

References:
[1]. Ahn K, et al. Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry. 2007 Nov 13;46(45):13019-30.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
959151-50-9
同义词
N-苯基-4-(3-喹啉基甲基)-1-哌啶甲酰胺
化学名
N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide
SMILES
O=C(NC1=CC=CC=C1)N2CCC(CC3=CC4=CC=CC=C4N=C3)CC2
分子式
C22H23N3O
分子量
345.44 g/mol
溶解性
DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:5): 0.125 mg/ml,Ethanol: 1 mg/ml
保存条件
Store at RT
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol