GlpBio

Niraparib metabolite M1 (Niraparib carboxylic acid metabolite M1)

目录号: GC33452纯度: >99.50%同义词: 尼拉帕尼代谢物; Niraparib carboxylic acid metabolite M1; M1 metabolite of niraparib
Niraparib 代谢物 M1 (Niraparib carboxy acid metabolite M1) 是 niraparib 的代谢物，后者作为一种新型聚 (ADP-核糖) 聚合酶 (PARP) 抑制剂。
Niraparib metabolite M1 (Niraparib carboxylic acid metabolite M1)
Cas No.: 1476777-06-6
规格价格库存数量操作
1mg¥1,350.00现货
1
5mg¥3,960.00现货
1
10mM (in 1mL DMSO)¥2,800.00现货
1
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产品描述 Description

Niraparib metabolite M1 is a metabolite of niraparib, and the latter one acts as a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.

Niraparib metabolite M1 has the validation in plasma and urine for the support of clinical studies such as the mass balance study and the absolute bioavailability study[1].

[1]. van Andel L, et al. Liquid chromatography-tandem mass spectrometry assay for the quantification of niraparib and its metabolite M1 in human plasma and urine. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Nov 19;1040:14-21.

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
1476777-06-6
同义词
尼拉帕尼代谢物; Niraparib carboxylic acid metabolite M1; M1 metabolite of niraparib
SMILES
O=C(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C12)O
分子式
C19H19N3O2
分子量
321.37 g/mol
溶解性
DMSO : ≥ 100 mg/mL (311.17 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol