GlpBio

GSK467

目录号: GC34604纯度: >99.00%
GSK467 is a cell penetrant and selective inhibitor of KDM5B (JARID1B/PLU1) with Ki of 10 nM. GSK467 shows apparent 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other JmJ family members.
GSK467
Cas No.: 1628332-52-4
规格价格库存数量操作
1mg¥666.00现货
1
5mg¥1,665.00现货
1
10mg¥2,502.00现货
1
10mM (in 1mL DMSO)¥1,832.00现货
1
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文献被引

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产品描述 Description

GSK467 is a cell penetrant and selective inhibitor of KDM5B (JARID1B/PLU1) with Ki of 10 nM. GSK467 shows apparent 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other JmJ family members.

[1] Johansson C, et al. Nat Chem Biol. 2016 Jul;12(7):539-45.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
1628332-52-4
SMILES
O=C1C2=C(NC(OC3=CN(N=C3)CC4=CC=CC=C4)=N1)C=NC=C2
分子式
C17H13N5O2
分子量
319.32 g/mol
溶解性
DMSO : 20.83 mg/mL (65.23 mM);Water : < 0.1 mg/mL (insoluble)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol