Cardiotoxin Analog (CTX) IV (6-12) (TFA) is a peptide fragment of Cardiotoxin Analog (CTX) IV. Cardiotoxin Analog (CTX) IV is one of the five cardiotoxin isoforms isolated from the venom of the Taiwan cobra (Naja naja atra)[1]. Cardiotoxin Analog (CTX) IV possesses arginine at the N-terminal end and is the only cardiotoxin isoform known so far that possesses a positively charged residue at the N-terminal amino acid[2].
References:
[1] Jayaraman G, Kumar TK, Tsai CC, et al. Elucidation of the solution structure of cardiotoxin analogue V from the Taiwan cobra (Naja naja atra)--identification of structural features important for the lethal action of snake venom cardiotoxins. Protein Sci. 2000;9(4):637-646.
[2] Jang JY, Krishnaswamy T, Kumar S, et al. Comparison of the hemolytic activity and solution structures of two snake venom cardiotoxin analogues which only differ in their N-terminal amino acid. Biochemistry. 1997;36(48):14635-14641.
Cardiotoxin Analog (CTX) IV (6-12) (TFA)是Cardiotoxin Analog (CTX) IV的一段肽段。Cardiotoxin Analog (CTX) IV是从台湾眼镜蛇（Naja naja atra）毒液中分离出的五种心脏毒素亚型之一[1]。Cardiotoxin Analog (CTX) IV的N端为精氨酸，是目前已知唯一在N端带有正电荷残基的蛇毒心脏毒素亚型[2]。