GlpBio

VS-5584 analog

目录号: GC48256纯度: >98.00%同义词: Desmethyl-SB2343
A dual inhibitor of PI3Kα and mTOR
VS-5584 analog
Cas No.: 1246535-95-4
规格价格库存数量操作
1 mg¥678.00现货
1
5 mg¥2,978.00现货
1
10 mg¥5,251.00现货
1
25 mg¥10,657.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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产品描述 Description

VS-5584 analog is a dual inhibitor of PI3Kα and mammalian target of rapamycin (mTOR; IC50s = 17 and 150 nM, respectively).1 It is a desmethyl analog of the dual PI3K/mTOR inhibitor VS-5584 .

1.Poulsen, A., Nagaraj, H., Lee, A., et al.Structure and ligand-based design of mTOR and PI3-kinase inhibitors leading to the clinical candidates VS-5584 (SB2343) and SB2602J. Chem. Inf. Model54(11)3238-3250(2014)

产品文档 Product Documents

Purity:>98.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
1246535-95-4
同义词
Desmethyl-SB2343
SMILES
CC(C)N(C=N1)C2=C1C(C3=CN=C(N)N=C3)=NC(N4CCOCC4)=N2
分子式
C16H20N8O
分子量
340.4 g/mol
溶解性
Chloroform: 0.5mg/mL
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol