Tricosanoic acid is a naturally occurring saturated fatty acid that has been found in various edible mushroom species.1 It inhibits lysis of human erythrocytes induced by S. aureus delta toxin in a concentration-dependent manner.2 Tricosanoic acid levels are decreased in the sebum of patients with papulopustular rosacea and increased in malignant, but not adjacent nonmalignant, prostate tissue in patients with prostate cancer.3,4 Tricosanoic acid has been used as an internal standard for the quantification of fatty acids in chicken egg yolk.5
1.Ribeiro, B., Guedes de Pinho, P., Andrade, P.B., et al.Fatty acid composition of wild edible mushrooms species: A comparative studyMicrochem. J.93(1)29-35(2009) 2.Kapral, F.A.Effect of fatty acids on Staphylococcus aureus delta-toxin hemolytic activityInfect. Immun.13(1)114-119(1976) 3.Ní Raghallaigh, S., Bender, K., Lacey, N., et al.The fatty acid profile of the skin surface lipid layer in papulopustular rosaceaBr. J. Dermatol.166(2)279-287(2012) 4.Jung, K., Reszka, R., Kamlage, B., et al.Tissue metabolite profiling identifies differentiating and prognostic biomarkers for prostate carcinomaInt. J. Cancer133(12)2914-2924(2013) 5.Wang, Y., Sunwoo, H., Cherian, G., et al.Fatty acid determination in chicken egg yolk: A comparison of different methodsPoult. Sci.79(8)1168-1171(2000)