Metaproterenol is a β2-adrenergic receptor (β2-AR) agonist with bronchodilator actions. It inhibits TGF-α-induced hepatocyte DNA synthesis and proliferation in vitro (IC50 = 15 nM), an effect that is reversed by the β2-AR antagonist butoxamine but not the β1-AR antagonist metoprolol . Metaproterenol dose-dependently relaxes lung strips and increases heart rate and inotropy of right atria and left atria, respectively, isolated from guinea pig (pD2s = 6.4, 7.08, and 6.61, respectively). Formulations containing metaproterenol were previously used as long-acting bronchodilators for the treatment of asthma.
Metaproterenol (hemisulfate)
目录号: GC44169纯度: >99.50%同义词: 硫酸奥西那林,Orciprenaline hemisulfate
A long-acting β2-adrenergic receptor agonist
Cas No.: 5874-97-5
| 规格 | 价格 | 库存 | 数量 | 操作 |
|---|---|---|---|---|
| 5mg | ¥120.00 | 现货 | 1 | |
| 10mg | ¥163.00 | 现货 | 1 | |
| 25mg | ¥253.00 | 现货 | 1 | |
| 50mg | ¥350.00 | 现货 | 1 | |
| 100mg | ¥490.00 | 现货 | 1 | |
| 200mg | ¥743.00 | 现货 | 1 | |
| 10mM (in 1mL DMSO) | ¥132.00 | 现货 | 1 |
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Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
产品描述 Description
产品文档 Product Documents
Purity:>99.50%Appearance:A solid
化学性质Chemical Properties
CAS 号
5874-97-5
同义词
硫酸奥西那林,Orciprenaline hemisulfate
SMILES
OC1=CC(O)=CC(C(CNC(C)C)O)=C1.OC2=CC(O)=CC(C(CNC(C)C)O)=C2.O=S(O)(O)=O
分子式
C11H17NO3•1/2H2SO4
分子量
260.3 g/mol
溶解性
DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。
计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度
g/mol
