Spiro-oxanthromicin A is a polyketide that has been found in Streptomyces.1 It induces mislocalization of K-RAS in MDCK cells (IC50 = 26.7 µM).
1.Salim, A.A., Xiao, X., Cho, K.J., et al.Rare Streptomyces sp. polyketides as modulators of K-Ras localisationOrg. Biomol. Chem.12(27)4872-4878(2014)
















