Kinase inhibitor-1

目录号: GC36392纯度: >99.00%
Kinase inhibitor-1 是 Tarloxotinib 的活性代谢物,是一种不可逆的 pan-ErbB TKI(Kinase inhibitor-1)。

Kinase inhibitor-1
Cas No.: 2135696-72-7
规格价格库存数量操作
5mg¥4,050.00现货
1
10mg¥0.01现货
1
50mg¥0.01现货
1
10mM (in 1mL DMSO)¥4,455.00现货
1

文献被引

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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Kinase inhibitor-1 (Compound 5) is a kinase inhibitor[1]. Kinase[1]

Kinases represent a large family of enzymes that catalyse the phosphorylation of proteins, lipids and metabolites and play a central role in the regulation of a wide variety of cellular processes. Abnormal kinase activity has been related to a wide range of disorders, including cancers[1].

[1]. Jeffrey Bruce Smaill, et al. Kinase inhibitors, prodrug forms thereof and their use in therapy. US9101632B2.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
2135696-72-7
SMILES
BrC1=C(Cl)C=CC(NC2=NC=NC3=CN=C(NC(/C=C/CN(C)C)=O)C=C32)=C1
分子式
C19H18BrClN6O
分子量
461.74 g/mol
溶解性
DMSO: 100 mg/mL (216.57 mM); Water: < 0.1 mg/mL (insoluble)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol