关于 "Bile Acids & Microbiome" 的结果211+ 个结果

Xanthurenic acid是一种内源性II组代谢型谷氨酸受体激动剂，参与丘脑的感觉传递。

Kainic acid (KA)是一种类似于兴奋毒性神经递质谷氨酸的物质。

Asiatic acid是一种五环三萜类化合物，可抑制EGFR活性，对野生型EGFR和T790M/L858R EGFR的IC 50 值分别为0.035nM和0.348nM。

A triterpenoid with diverse biological activities

A trans fatty acid

Hippuric acid (2-Benzamidoacetic acid) 是一种口服活性代谢物。

Pimelic acid (Heptanedioic acid, 1,5-Pentanedicarboxylic acid, 1,7-Heptanedioic acid) originating from fatty acid synthesis pathway is a bona fide precursor of biotin in B. subtilis.

Gambogenic acid是藤黄的主要活性成分，能抑制Aurora A激酶，IC 50 值为1.425μM。

An active metabolite of temozolomide

Chicoric acid是一种羟基肉桂酸，属于苯丙醇类有机化合物，存在于菊苣、 蒲公英和罗勒等多种植物中，具有抗氧化、抗炎、抗糖尿病、抗病毒等多种生物活性。

Minodronic acid (YM529, ONO-5920) is a third-generation nitrogen-cotaining bisphosphonate that is used for the treatment of osteoporosis. Minodronic acid is an aminobisphosphonate that is a selective antagonist of purinergic P2X2/3 receptors involved in pain.

Ursonic acid (Prunol, Malol, beta-Ursolic acid, NSC4060, CCRIS 7123, TOS-BB-0966), present in many plants, is a pentacyclic triterpenoid that can be used as a cosmetics additive and serve as a starting material for synthesis of more potent bioactive derivatives, such as experimental antitumor agents. Ursonic acid induces the apoptosis of human cancer cells through multiple signaling pathways.

Glycolithocholic Acid是次级胆汁酸与甘氨酸的结合物，为体内内源性代谢产物。

A plant hormone with diverse roles

(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid))是一种新型的、具有口服活性的Bcl-2家族蛋白抑制剂，可抑制Bcl-2（K i =260±30nM），Mcl-1（K i =170±10nM）和Bcl-xL（K i =480±40nM）。

D-?Glucosamic acid 是一种内源性代谢产物。

A bisphosphonate that inhibits bone resorption

2-Formylphenoxyacetic acid (2-Carboxymethoxybenzaldehyde) 是一种药物中间体，用于合成各种活性化合物。

UDP-g acid 是一种用于生产多糖的糖，是抗坏血酸生物合成的中间体。