关于 "Bile Acids & Microbiome" 的结果211+ 个结果
- Asiatic acidCAS: 464-92-6
Asiatic acid是一种五环三萜类化合物,可抑制EGFR活性,对野生型EGFR和T790M/L858R EGFR的IC 50 值分别为0.035nM和0.348nM。
- Hippuric acid (2-Benzamidoacetic acid)CAS: 495-69-2
Hippuric acid (2-Benzamidoacetic acid) 是一种口服活性代谢物。
- Pimelic acid (1,5-Pentanedicarboxylic acid)CAS: 111-16-0
Pimelic acid (Heptanedioic acid, 1,5-Pentanedicarboxylic acid, 1,7-Heptanedioic acid) originating from fatty acid synthesis pathway is a bona fide precursor of biotin in B. subtilis.
- Chicoric acidCAS: 6537-80-0
Chicoric acid是一种羟基肉桂酸,属于苯丙醇类有机化合物,存在于菊苣、 蒲公英和罗勒等多种植物中,具有抗氧化、抗炎、抗糖尿病、抗病毒等多种生物活性。
- Minodronic acidCAS: 180064-38-4
Minodronic acid (YM529, ONO-5920) is a third-generation nitrogen-cotaining bisphosphonate that is used for the treatment of osteoporosis. Minodronic acid is an aminobisphosphonate that is a selective antagonist of purinergic P2X2/3 receptors involved in pain.
- Ursonic acidCAS: 6246-46-4
Ursonic acid (Prunol, Malol, beta-Ursolic acid, NSC4060, CCRIS 7123, TOS-BB-0966), present in many plants, is a pentacyclic triterpenoid that can be used as a cosmetics additive and serve as a starting material for synthesis of more potent bioactive derivatives, such as experimental antitumor agents. Ursonic acid induces the apoptosis of human cancer cells through multiple signaling pathways.
- (R)-(-)-Gossypol acetic acid (AT-101 (acetic acid))CAS: 866541-93-7
(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid))是一种新型的、具有口服活性的Bcl-2家族蛋白抑制剂,可抑制Bcl-2(K i =260±30nM),Mcl-1(K i =170±10nM)和Bcl-xL(K i =480±40nM)。
- 2-Formylphenoxyacetic acidCAS: 6280-80-4
2-Formylphenoxyacetic acid (2-Carboxymethoxybenzaldehyde) 是一种药物中间体,用于合成各种活性化合物。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC11459 | Xanthurenic acid | 59-00-7 | mGluR | ||
Xanthurenic acid是一种内源性II组代谢型谷氨酸受体激动剂,参与丘脑的感觉传递。 | |||||
| GC16667 | Kainic acid | 487-79-6 | Kainate Receptors | ||
Kainic acid (KA)是一种类似于兴奋毒性神经递质谷氨酸的物质。 | |||||
| GN10702 | Asiatic acid | 464-92-6 | Parasite | ||
Asiatic acid是一种五环三萜类化合物,可抑制EGFR活性,对野生型EGFR和T790M/L858R EGFR的IC50值分别为0.035nM和0.348nM。 | |||||
| GN10390 | Ursolic acid | 77-52-1 | Autophagy | ||
A triterpenoid with diverse biological activities | |||||
| GC33773 | Elaidic acid | 112-79-8 | Endogenous Metabolite | ||
A trans fatty acid | |||||
| GC33778 | Hippuric acid (2-Benzamidoacetic acid) | 495-69-2 | Endogenous Metabolite | ||
Hippuric acid (2-Benzamidoacetic acid) 是一种口服活性代谢物。 | |||||
| GC33811 | Pimelic acid (1,5-Pentanedicarboxylic acid) | 111-16-0 | Endogenous Metabolite | ||
Pimelic acid (Heptanedioic acid, 1,5-Pentanedicarboxylic acid, 1,7-Heptanedioic acid) originating from fatty acid synthesis pathway is a bona fide precursor of biotin in B. subtilis. | |||||
| GC38062 | Gambogenic acid | 173932-75-7 | Histone Methyltransferase | ||
Gambogenic acid是藤黄的主要活性成分,能抑制Aurora A激酶,IC50值为1.425μM。 | |||||
| GC52076 | Temozolomide Acid | 113942-30-6 | Drug Metabolite | ||
An active metabolite of temozolomide | |||||
| GC64993 | Chicoric acid | 6537-80-0 | Reactive Oxygen Species | ||
Chicoric acid是一种羟基肉桂酸,属于苯丙醇类有机化合物,存在于菊苣、 蒲公英和罗勒等多种植物中,具有抗氧化、抗炎、抗糖尿病、抗病毒等多种生物活性。 | |||||
| GC36613 | Minodronic acid | 180064-38-4 | Other Apoptosis | ||
Minodronic acid (YM529, ONO-5920) is a third-generation nitrogen-cotaining bisphosphonate that is used for the treatment of osteoporosis. Minodronic acid is an aminobisphosphonate that is a selective antagonist of purinergic P2X2/3 receptors involved in pain. | |||||
| GC37873 | Ursonic acid | 6246-46-4 | Other Apoptosis | ||
Ursonic acid (Prunol, Malol, beta-Ursolic acid, NSC4060, CCRIS 7123, TOS-BB-0966), present in many plants, is a pentacyclic triterpenoid that can be used as a cosmetics additive and serve as a starting material for synthesis of more potent bioactive derivatives, such as experimental antitumor agents. Ursonic acid induces the apoptosis of human cancer cells through multiple signaling pathways. | |||||
| GC43778 | Glycolithocholic Acid | 474-74-8 | Bile Acids & Microbiome | ||
Glycolithocholic Acid是次级胆汁酸与甘氨酸的结合物,为体内内源性代谢产物。 | |||||
| GC20006 | (±)-Abscisic acid | 14375-45-2 | - | ||
A plant hormone with diverse roles | |||||
| GC34096 | (R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) | 866541-93-7 | Autophagy | ||
(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid))是一种新型的、具有口服活性的Bcl-2家族蛋白抑制剂,可抑制Bcl-2(Ki=260±30nM),Mcl-1(Ki=170±10nM)和Bcl-xL(Ki=480±40nM)。 | |||||
| GC62919 | D-Glucosamic acid | 3646-68-2 | Endogenous Metabolite | ||
D-?Glucosamic acid 是一种内源性代谢产物。 | |||||
| GC45187 | Zoledronic Acid (hydrate) | 165800-06-6 | Autophagy | ||
A bisphosphonate that inhibits bone resorption | |||||
| GD41269 | 2-Formylphenoxyacetic acid | 6280-80-4 | - | ||
2-Formylphenoxyacetic acid (2-Carboxymethoxybenzaldehyde) 是一种药物中间体,用于合成各种活性化合物。 | |||||
| GC26596 | UDP-g acid | 2616-64-0 | - | ||
UDP-g acid 是一种用于生产多糖的糖,是抗坏血酸生物合成的中间体。 | |||||
