关于 "GABA Receptor" 的结果24+ 个结果
- γ-Aminobutyric acid (GABA)CAS: 56-12-2
GABA是哺乳动物大脑中一种重要的内源性抑制性神经递质，对GABA A 受体的α6、α1、α4和α5亚基的EC 50 值分别为0.17、2.1、2.1和1.4μM。
- Galanin Receptor Ligand M35CAS: 142846-71-7
Galanin Receptor Ligand M35 是一种高亲和力的甘丙肽受体配体，在大鼠脊髓、大鼠海马和离体小鼠胰岛中起着甘丙肽受体拮抗剂的作用。Galanin Receptor Ligand M35 对人 GalR1 和 GalR2 的 Ki 值分别为 0.11 nM、2.0 nM。
- MC-Gly-Gly-Phe-Gly-GABA-ExatecanCAS: 1599439-52-7
MC-Gly-Gly-Phe-Gly-GABA-Exatecan是ADC的试剂-接头偶联物，与拓扑异构酶Exatecan抑制剂结合，IC50为22μM。
- Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2, (trifluoroacetate salt)
A neuropeptide with diverse biological activities
- Dabcyl-GABA-RPKPVE-Nva-WR-Glu(EDANS)-AK-NH2 (trifluoroacetate salt)
A fluorogenic substrate for MMP-3
- A2A receptor antagonist 1CAS: 443103-97-7
A2Areceptorantagonist1是adenosineA2Areceptor和A1receptor的拮抗剂,Ki值分别为4和264nM。
- GABAA receptor agent 1CAS: 1571-87-5
GABAA receptor agent 1 is a high affinity ligand for Gamma-aminobutyric acid A (GABAA) receptor that exerts potent anticonvulsant activity.
- Thrombin Receptor AntagonistCAS: 207553-92-2
The peptide T1, MSRPACPNDKYE, is based on the sequence of the thrombin receptor domain that functions as a tethered ligand for the receptor itself. T1 has been selected from a phage peptide library as an inhibitor of thrombin triggered platelet aggregation, serotonin release and tyrosine phosphorylation. Its anti-aggregatory activity was about ten-fold higher than that of the previously reported peptide antagonists of the thrombin receptor. MSRPACPNDKYE has served as model peptide in protein modification and MS studies.
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC46339 | (R)-4-Amino-3-hydroxybutyric Acid | 7013-07-2 | Seizure Disorders | ||
A GABA receptor modulator | |||||
| GC17321 | RuBi-GABA | 1028141-88-9 | GABA Receptor | ||
RuBi-GABA 是一种新型的钌基笼状 GABA 化合物。 | |||||
| GC12506 | 3-Methyl-GABA | 71424-95-8 | GABA Receptor | ||
3-Methyl-GABA 是一种有效的 GABA 氨基转移酶激活剂。 | |||||
| GA11007 | Boc-GABA-OH | 57294-38-9 | PROTAC Linker | ||
Boc-GABA-OH 是一种 PROTAC 接头，可用于合成 UNC6852，一种 EED 靶向 PROTAC。 | |||||
| GC50000 | γ-Aminobutyric acid (GABA) | 56-12-2 | - | ||
GABA是哺乳动物大脑中一种重要的内源性抑制性神经递质，对GABAA受体的α6、α1、α4和α5亚基的EC50值分别为0.17、2.1、2.1和1.4μM。 | |||||
| GC14150 | DPNI-caged-GABA | 927866-58-8 | GABA Receptor | ||
activates GABAA receptor | |||||
| GC11612 | RuBi GABA trimethylphosphine | - | GABA Receptor | ||
GABAB receptor agonist | |||||
| GC70650 | γ-Acetylenic GABA hydrochloride | 103451-26-9 | GABA Receptor | ||
γ-Acetylenic GABA hydrochloride是GABA转氨酶的不可逆抑制剂。 | |||||
| GC33504 | 4-Acetamidobutanoic acid (N-acetyl GABA) | 3025-96-5 | Endogenous Metabolite | ||
A GABA derivative | |||||
| GC36102 | Galanin Receptor Ligand M35 | 142846-71-7 | Peptides | ||
Galanin Receptor Ligand M35 是一种高亲和力的甘丙肽受体配体，在大鼠脊髓、大鼠海马和离体小鼠胰岛中起着甘丙肽受体拮抗剂的作用。Galanin Receptor Ligand M35 对人 GalR1 和 GalR2 的 Ki 值分别为 0.11 nM、2.0 nM。 | |||||
| GA10603 | Z-GABA-OH,Z-gama-Abu-OH | 5105-78-2 | Others | ||
Z-GABA-OH,Z-gama-Abu-OH | |||||
| GC73889 | MC-Gly-Gly-Phe-Gly-GABA-Exatecan | 1599439-52-7 | Drug-Linker Conjugates for ADC | ||
MC-Gly-Gly-Phe-Gly-GABA-Exatecan是ADC的试剂-接头偶联物，与拓扑异构酶Exatecan抑制剂结合，IC50为22μM。 | |||||
| GC11275 | C34 | 40592-88-9 | HSC | ||
C34是一种可口服的Toll样受体4(TLR4)选择性拮抗剂，C34通过抑制TLR4/MyD88/NF-κB信号通路，减少促炎细胞因子的产生，从而发挥抗炎作用。 | |||||
| GC47164 | Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2, (trifluoroacetate salt) | - | Proteolysis | ||
A neuropeptide with diverse biological activities | |||||
| GC43369 | Dabcyl-GABA-RPKPVE-Nva-WR-Glu(EDANS)-AK-NH2 (trifluoroacetate salt) | - | Proteolysis | ||
A fluorogenic substrate for MMP-3 | |||||
| GC43083 | C3a Receptor Agonist | 944997-60-8 | Neuroscience | ||
C3a Receptor Agonist是一种选择性的补体3a受体（C3aR）特异性激动剂。 | |||||
| GC16363 | TGR5 Receptor Agonist | 1197300-24-5 | GPCR19 | ||
A TGR5 agonist | |||||
| GP20716 | Leptin Receptor Human | - | Leptin | ||
Leptin Binding Domain Human Recombinant | |||||
| GP20717 | Leptin Receptor Chicken | - | Leptin | ||
Leptin Receptor Chicken Recombinant | |||||
| GP20896 | sRANK Receptor Human | - | RANK Ligand | ||
Soluble RANK Receptor Human Recombinant | |||||
| GC32019 | Interferon receptor agonist | 2215120-36-6 | IFNAR | ||
干扰素受体激动剂（化合物 6）是一种干扰素 (IFN) 受体诱导剂。 | |||||
| GC30918 | A2A receptor antagonist 1 | 443103-97-7 | Adenosine Receptor | ||
A2Areceptorantagonist1是adenosineA2Areceptor和A1receptor的拮抗剂,Ki值分别为4和264nM。 | |||||
| GC60862 | GABAA receptor agent 1 | 1571-87-5 | GABA Receptor | ||
GABAA receptor agent 1 is a high affinity ligand for Gamma-aminobutyric acid A (GABAA) receptor that exerts potent anticonvulsant activity. | |||||
| GA23607 | Thrombin Receptor Antagonist | 207553-92-2 | - | ||
The peptide T1, MSRPACPNDKYE, is based on the sequence of the thrombin receptor domain that functions as a tethered ligand for the receptor itself. T1 has been selected from a phage peptide library as an inhibitor of thrombin triggered platelet aggregation, serotonin release and tyrosine phosphorylation. Its anti-aggregatory activity was about ten-fold higher than that of the previously reported peptide antagonists of the thrombin receptor.
MSRPACPNDKYE has served as model peptide in protein modification and MS studies. | |||||