GlpBio

Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2, (trifluoroacetate salt)

目录号: GC47164纯度: >95.00%同义词: MMP Fluorogenic Substrate III
A neuropeptide with diverse biological activities
Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2, (trifluoroacetate salt)
Cas No.: N/A
规格价格库存数量操作
500 μg¥5,069.00现货
1
电话: 400-920-5774Email: sales@glpbio.cn

文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-2, MMP-3, and MMP-9.1 Upon enzymatic cleavage by MMP-1, MMP-2, MMP-3, or MMP-9 at the Gly-Leu site, EDANS is separated from the Dabcyl quencher and its fluorescence can be used to quantify MMP-1, MMP-2, MMP-3, and MMP-9 activity.1,2 EDANS displays excitation/emission maxima of 340/485 nm, respectively.

1.Beekman, B., Drijfhout, J.W., Bloemhoff, W., et al.Convenient fluorometric assay for matrix metalloproteinase activity and its application in biological mediaFEBS Lett.390(2)221-225(1996) 2.Krismastuti, F.S.H., Pace, S., and Voelcker, N.H.Porous silicon resonant microcavity biosensor for matrix metalloproteinase detectionAdv. Funct. Mater.24(23)3639-3650(2014)

产品文档 Product Documents

Purity:>95.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
N/A
同义词
MMP Fluorogenic Substrate III
SMILES
CN(C)C1=CC=C(/N=N/C2=CC=C(C(NCCCC(N3[C@H](C(N[C@@H](CCC(N)=O)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCC(NCCNC4=CC=CC5=C4C=CC=C5S(O)(=O)=O)=O)C(N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)C)=O)=O)=O)=O)=O)CCC3)=O)=O)C=C2)C=C1.FC(F)(C(O)=O)F
分子式
C63H88N16O14S.XCF3COOH
分子量
1325.5 g/mol
溶解性
Formic Acid: 1 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol