关于 "Ligand for E3 Ligase" 的结果28+ 个结果

Pomalidomide-PEG1-C2-N3是一种合成的E3连接酶配体-linker偶联物，包含基于Pomalidomide的cereblon配体和1个单元PEG的linker。Pomalidomide-PEG1-C2-N3可通过PROTAC技术合成选择性的CDK6降解剂CP-10。CP-10诱导CDK6降解，DC50为2.1nM。

(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 (S,R,S)-AHPC 的 VHL 配体和 5 个单元 PEG linker。

三(3-羟丙基三唑甲基)胺(THPTA) ligand是一种水溶性配体。

Functionalized von-Hippel-Lindau protein ligand (VHL) for research and development; incorporates an E3 ligase ligand plus alkylC3 linker with terminal carboxylic acid ready for conjugation to a target protein ligand

FAP Ligand 1（FL）是一种高亲和力FAP小分子配体，用于将附着的药物靶向表达FAP的成纤维细胞，可用于靶向癌症的放射成像研究。

RNF114 ligand 1是E3泛素连接酶粘合剂。

hRIO2 kinase ligand-1（com 9）是hRIO2激酶的配体，Kd值为520 nM。

凝血酶受体激活剂 5 (TRAP-5) 也称为凝血因子 II 受体 (1-5) 或蛋白酶激活受体 1 (1-5)，用于研究冠心病 (CHD)。

A TLR7 agonist

Thalidomide-NH-CBP/p300 ligand 2 (P-007) 是 CBP 和 p300 的 PROTAC 降解剂。

A red fluorescent dye

Functionalized cereblon ligand for research and development; incorporates an E3 ligase ligand plus an alkylC3 linker with terminal acid ready for conjugation to a target protein ligand

A PD-1/PD-L1 interaction inhibitor

Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal amine ready for conjugation to a target protein ligand

Functionalized cereblon ligand for PROTAC(R) research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal acid ready for conjugation to a target protein ligand

Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG2 linker with terminal amine ready for conjugation to a target protein ligand

Functionalized cereblon ligand for PROTAC(R) research and development; incorporates an E3 ligase ligand plus an alkylC6 linker with terminal acid ready for conjugation to a target protein ligand

Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG3 linker with terminal amine ready for conjugation to a target protein ligand

Functionalized cereblon ligand for PROTAC(R) research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal acid ready for conjugation to a target protein ligand

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand

Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC1-PEG3-alkylC3 linker with terminal amine ready for conjugation to a target protein ligand

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus alkylC2 linker with terminal carboxylic acid ready for conjugation to a target protein ligand

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal amine ready for conjugation to a target protein ligand

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus alkylC6 linker with terminal carboxylic acid ready for conjugation to a target protein ligand