Sulforhodamine 101

目录号: GC12347纯度: >98.00%同义词: 磺基罗丹明 101; Sulforhodamine 101; SR101

A red fluorescent dye

Cas No.: 60311-02-6

规格	价格	库存	数量	操作
50mg	¥452.00	现货	1

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Nature
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618, 1017–1023 (2023)
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610, 366–372 (2022)
Cell
187(9):2288-2304 (2024)
Cell
183(7):1867-1883 (2020)
Science
388(6745) (2025)
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387(6739) (2025)
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387(6734) (2025)
Cell Research
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产品描述 Description

Sulforhodamine 101 is a red fluorescent dye.

Sulforhodamine 101 does not label astrocytes in brainstem slices as strong and specific as in the hippocampus or cortex. To minimize excitatory side effects, the concentration of Sulforhodamine 101 has to be kept as low as possible or the labeling procedure can be performed after the actual experiment[1].

In vivo, epileptic activity can be induced by intra-hippocampal injection of small volumes of 10 μM Sulforhodamine 101 or topical application of 100 μM[1].

References:
[1]. Hülsmann S, et al. Limitations of Sulforhodamine 101 for Brain Imaging. Front Cell Neurosci. 2017 Feb 28;11:44.

实验参考方法 Experimental Reference Method

Cell experiment:

Acute brain slices are usually incubated in carbonated extracellular solution containing 0.5 to1 μM Sulforhodamine 101 for 20 to 30 min and 34 to 37°C. Following this, excess dye is removed over a period of 10 to 30 min using different protocols that were described earlier[1].

Animal experiment:

For in vivo imaging, Sulforhodamine 101 (SR101) is applied topically at concentrations of 250 nM to 300 μM or by bolus injection. Additionally, Sulforhodamine 101 injection over the tail vein (10 mg/mL) has been reported to be successful[1].

References:

[1]. Hülsmann S, et al. Limitations of Sulforhodamine 101 for Brain Imaging. Front Cell Neurosci. 2017 Feb 28;11:44.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号

60311-02-6

同义词

磺基罗丹明 101; Sulforhodamine 101; SR101

化学名

A name could not be generated for this structure.

SMILES

[O-]S(=O)(C1=CC(S(O)(=O)=O)=CC=C1C2=C3C(OC(C2=C4)=C5C6=C4CCCN6CCC5)=C7C(C8=C3)=[N+](CCC8)CCC7)=O

分子式

C₃₁H₃₀N₂O₇S₂

分子量

606.71 g/mol

溶解性

DMF: 20 mg/ml,DMSO: 25 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 2 mg/ml

保存条件

Store at -20°C, protect from light

General tips

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。

Shipping Condition

评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

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分子量 (MW)

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