GlpBio

Reverse Transcriptase

Reverse Transcriptase(逆转录酶)

Reverse transcriptase, also known as RNA-directed DNA polymerase catalyzes the transcription of RNA into DNA. It is key to the retroviruses infection.

Reverse Transcriptase 相关产品(65)

  • GC32381 structure
    GC32381BF738735
    CAS: 1436383-95-7
    纯度: >99.00%

    BF738735是一种磷脂酰肌醇4-激酶IIIβ(PI4KIIIβ)抑制剂，IC50为5.7nM。

  • GC33536 structure
    GC33536Etravirine D4 (TMC-125 D4)
    CAS: 1142095-93-9

    Etravirine D4 (TMC-125 D4) (TMC-125 D4) 是氘标记的 Etravirine。

  • GC33990 structure
    GC339902,2'-Anhydrouridine (2,2'-Cyclouridine)
    CAS: 3736-77-4
    纯度: >98.00%

    An inhibitor of uridine phosphorylase

  • GC35130 structure
    GC351304'-Ethynyl-2'-deoxyadenosine
    CAS: 306305-07-7

    4'-Ethynyl-2'-deoxyadenosine (4'-E-dA)，是一种核苷逆转录酶 (RT) 抑制剂， 是一种抗病毒药物，对耐药HIV变异型具有较强的抑制作用，在MT-4细胞中，EC50 值为 98 nM。

  • GC35731 structure
    GC35731Corydine
    CAS: 476-69-7

    An aporphine alkaloid with diverse biological activities

  • GC35835 structure
    GC35835Delavirdine
    CAS: 136817-59-9

    A non-nucleoside reverse transcriptase inhibitor

  • GC37674 structure
    GC37674SPK-601
    CAS: 1096687-52-3
    纯度: >98.00%

    SPK-601(LMV-601)是卵磷脂特异磷脂酶C（PC-PLC）抑制剂，可用作抗菌剂。

  • GC37690 structure
    GC37690Stavudine sodium
    CAS: 134624-73-0

    An inhibitor of HIV reverse transcriptase

  • GC37758 structure
    GC37758Tenofovir alafenamide fumarate
    CAS: 379270-38-9
    纯度: >99.50%

    Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.

  • GC37759 structure
    GC37759Tenofovir alafenamide hemifumarate
    CAS: 1392275-56-7
    纯度: >99.50%

    Tenofovir alafenamide hemifumarate是HIV-1核苷酸逆转录酶（RT）的前药。

  • GC37760 structure
    GC37760Tenofovir Disoproxil
    CAS: 201341-05-1
    纯度: >99.50%

    A prodrug of the antiviral tenofovir

  • GC42731 structure
    GC42731Adefovir
    CAS: 106941-25-7
    纯度: >98.00%

    An active metabolite of adefovir dipivoxil

  • GC42784 structure
    GC42784AMI-1 (sodium salt)
    纯度: >99.00%

    A cell permeable inhibitor of PRMTs

  • GC43600 structure
    GC43600Emtricitabine S-oxide
    CAS: 152128-77-3
    纯度: >98.00%

    A potential impurity found in commercial emtricitabine preparations

  • GC45825 structure
    GC45825Etravirine-d6
    CAS: 1142096-06-7
    纯度: >99.00%

    An internal standard for the quantification of etravirine

  • GC46767 structure
    GC46767Abacavir-d4
    CAS: 1260619-56-4
    纯度: >99.00%

    An internal standard for the quantification of abacavir

  • GC47770 structure
    GC47770Nevirapine-d4
    CAS: 1051418-95-1
    纯度: >99.00%

    An internal standard for the quantification of nevirapine

  • GC48103 structure
    GC48103Stavudine-13C-d3
    CAS: 2750534-86-0
    纯度: >99.00%

    A neuropeptide with diverse biological activities

  • GC49022 structure
    GC49022Didanosine-d2
    CAS: 69655-05-6
    纯度: >99.00%

    An internal standard for the quantification of didanosine

  • GC60357 structure
    GC60357Tenofovir diphosphate
    CAS: 166403-66-3

    An HIV reverse transcriptase and HBV polymerase inhibitor

  • GC60358 structure
    GC60358Tenofovir diphosphate triethylamine
    CAS: 2122333-63-3

    Tenofovirdiphosphatetriethylamine(TFV-DPtriethylamine)是一种ATP竞争性的DNA聚合酶(DNApolymerases)抑制剂，且是1型HIV(HIV-1)逆转录酶(RT)的底物。

  • GC61134 structure
    GC61134Nigranoic acid
    CAS: 39111-07-4

    Nigranoicacid是五味子中分离得到的一种三萜类化合物。Nigranoicacid能抑制HIV-1逆转录酶。在脑缺血再灌注动物模型中，Nigranoicacid通过PARP/AIF信号通路保护大脑。

  • GC62223 structure
    GC62223Ro-0335
    CAS: 867365-76-2
    纯度: >99.50%

    An NNRTI and active metabolite of elsulfavirine

  • GC62607 structure
    GC62607EFdA-TP tetraammonium

    EFdA-TP tetraammonium 是一种有效的核苷逆转录酶 (RT) 抑制剂。EFdA-TP tetraammonium 作为有效的立即或延迟链终止剂 (ICT 或 DCT) 抑制 RT 催化的 DNA 合成。EFdA-TP tetraammonium 通过多种机制抑制 HIV-1 RT。