Autophagy
Autophagy(自噬)
Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.
Autophagy 相关产品(1140)
- GC48118Sunitinib-d10CAS: 1126721-82-1纯度: >99.00%
An internal standard for the quantification of sunitinib
- GC48124Tamoxifen-d5CAS: 157698-32-3纯度: >99.00%
An internal standard for the quantification of tamoxifen
- GC49016Dimethyl 2-ketoglutarateCAS: 13192-04-6纯度: >95.00% / >96.00% / >97.00%
An esterified form of α-ketoglutarate
- GC49189(E/Z)-4-hydroxy Tamoxifen-d5CAS: 2470232-57-4纯度: >99.00%
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen
- GC49308UngeremineCAS: 2121-12-2纯度: >98.00%
A betaine-type alkaloid with diverse biological activities
- GC49341Spermidine-d6CAS: 2514812-10-1纯度: >99.00%
An internal standard for the quantification of spermidine
- GC50009LY 294002 hydrochlorideCAS: 934389-88-5纯度: >98.00%
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
- GC50113Noradrenaline bitartrateCAS: 51-40-1纯度: >99.00%
Noradrenaline bitartrate是一种β1选择性肾上腺素受体激动剂，EC 50 值为5.37μM。
- GC50305Autocamtide-2-related inhibitory peptide, myristoylatedCAS: 201422-04-0
Autocamtide-2 相关抑制肽，肉豆蔻酰化是肉豆蔻酰化 Autocamtide-2 相关抑制肽。
- GC60159Ezetimibe ketoneCAS: 191330-56-0
Ezetimibe ketone (EZM-K) 是 Ezetimibe 的 I 期代谢产物。Ezetimibe 是一种 NPC1L1 抑制剂，是有效的 Nrf2 激活剂，Ezetimibe 还是有效的胆固醇吸收抑制剂。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC48118 | Sunitinib-d10 | 1126721-82-1 | >99.00% | |
An internal standard for the quantification of sunitinib | ||||
| GC48124 | Tamoxifen-d5 | 157698-32-3 | >99.00% | |
An internal standard for the quantification of tamoxifen | ||||
| GC48676 | Monascuspiloin | 1011244-19-1 | >85.00% | |
A fungal metabolite with anticancer activity | ||||
| GC48689 | SBP-7455 | 1884222-74-5 | >98.00% | |
A dual inhibitor of ULK1 and ULK2 | ||||
| GC49016 | Dimethyl 2-ketoglutarate | 13192-04-6 | >95.00% / >96.00% / >97.00% | |
An esterified form of α-ketoglutarate | ||||
| GC49084 | PHY34 | 2130033-55-3 | >98.00% | |
An inhibitor of late-stage autophagy | ||||
| GC49189 | (E/Z)-4-hydroxy Tamoxifen-d5 | 2470232-57-4 | >99.00% | |
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen | ||||
| GC49308 | Ungeremine | 2121-12-2 | >98.00% | |
A betaine-type alkaloid with diverse biological activities | ||||
| GC49341 | Spermidine-d6 | 2514812-10-1 | >99.00% | |
An internal standard for the quantification of spermidine | ||||
| GC49670 | Indium (III) thiosemicarbazone 5b | 2345755-20-4 | >95.00% | |
An anticancer agent | ||||
| GC49815 | Oleuropein aglycone | 31773-95-2 | >98.00% | |
A polyphenol with diverse biological activities | ||||
| GC50009 | LY 294002 hydrochloride | 934389-88-5 | >98.00% | |
Prototypical PI 3-kinase inhibitor; also inhibits other kinases | ||||
| GC50040 | SCIO 469 hydrochloride | 2387505-88-4 | - | |
A p38 MAPK inhibitor | ||||
| GC50067 | ML 3403 | 549505-65-9 | - | |
ML 3403 是一种有效的 p38 MAPK 抑制剂，IC50 为 0.38 μM。 | ||||
| GC50113 | Noradrenaline bitartrate | 51-40-1 | >99.00% | |
Noradrenaline bitartrate是一种β1选择性肾上腺素受体激动剂，EC 50 值为5.37μM。 | ||||
| GC50253 | PF 543 hydrochloride | 1706522-79-3 | >98.00% | |
A potent inhibitor of SPHK1 | ||||
| GC50305 | Autocamtide-2-related inhibitory peptide, myristoylated | 201422-04-0 | - | |
Autocamtide-2 相关抑制肽，肉豆蔻酰化是肉豆蔻酰化 Autocamtide-2 相关抑制肽。 | ||||
| GC52057 | QN523 | 878581-60-3 | >98.00% | |
An anticancer agent | ||||
| GC52477 | Corynoxine (hydrochloride) | - | >98.00% | |
An indole alkaloid | ||||
| GC60076 | Bigelovin | 3668-14-2 | >99.50% | |
Bigelovin是可从海百合中分离得到的一种倍半萜内酯，是选择性的视黄素X受体α(retinoidXreceptorα)的激动剂。Bigelovin可通过诱导凋亡和自噬来发挥抗肿瘤活性。Bigelovin通过抑制ROS的生成来调节mTOR信号通路。 | ||||
| GC60159 | Ezetimibe ketone | 191330-56-0 | - | |
Ezetimibe ketone (EZM-K) 是 Ezetimibe 的 I 期代谢产物。Ezetimibe 是一种 NPC1L1 抑制剂，是有效的 Nrf2 激活剂，Ezetimibe 还是有效的胆固醇吸收抑制剂。 | ||||
| GC60241 | Melatonin D5 | 66521-38-8 | - | |
An internal standard for the quantification of melatonin | ||||
| GC60245 | Metformin | 657-24-9 | >98.00% / >95.00% / >97.00% | |
二甲双胍（1,1-二甲基双胍）主要介导 AMPK 的激活，AMPK 是一种参与调节细胞能量代谢的丝氨酸/苏氨酸蛋白激酶，可导致癌细胞中 mTOR 信号传导和蛋白质合成的减少。 | ||||
| GC60325 | Rilmenidine | 54187-04-1 | - | |
An antihypertensive agent | ||||