Autophagy
Autophagy(自噬)
Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.
Autophagy 相关产品(1140)
- GC36671N-BenzyllinolenamideCAS: 883715-18-2
N-?Benzyllinolenamide 是从玛卡中得到的玛卡酰胺,为脂肪酰胺水解酶 (FAAH) 抑制剂,IC50 值为 41.8 μM。
- GC36690Nampt-IN-3CAS: 2121591-52-2纯度: >99.00%
Nampt-IN-3 (Compound 35) 同时抑制烟酰胺磷酸核糖转移酶 (NAMPT) 和 HDAC,IC50 分别为 31 nM 和 55 nM。Nampt-IN-3 有效诱导细胞凋亡 (apoptosis) 和自噬 (autophagy),最终导致细胞死亡。
- GC36703N-BenzyloleamideCAS: 883715-21-7纯度: >98.00%
N-Benzyloleamide 是从 Lepidium meyenii (Maca) 中分离出的一种 maccamide。N-Benzyloleamide 不可逆地抑制脂肪酸酰胺水解酶 (FAAH)。N-Benzyloleamide 影响能量代谢,显示抗氧化和抗疲劳活性。
- GC36736NicodicosapentCAS: 1269181-69-2纯度: >98.00%
Nicodicosapent 是一种脂肪酸烟酸共轭体,可以抑制固醇调节元件结合蛋白 (SREBP) 的活性,调节胆固醇代谢的蛋白质如 PCSK9,HMG-CoA reductase,ATP citrate lyase 和 NPC1L1 等的活性。
- GC36758Norepinephrine hydrochlorideCAS: 329-56-6纯度: >99.50% / >98.00%
Norepinephrine hydrochloride是一种作用于α1、α2、β1等肾上腺素能受体,具有收缩血管、调节血压等药理作用的儿茶酚胺类神经递质。
- GC36806Omeprazole D3CAS: 922731-01-9纯度: >98.50%
An internal standard for the quantification of omeprazole
- GC36855Paris saponin VIICAS: 68124-04-9纯度: >98.00% / >98.50%
Chonglou Saponin VII (Dioscinin, Polyphyllin-VII, Paris saponin-VII), a kind of steroidal saponins from Chonglou (Rhizoma Paridis Chonglou), inhibits EMT and reduces the invasion of ovarian cancer cells via the GSK-3β/β-catenin signaling pathway.
- GC36868Pennogenin 3-O-beta-chacotriosideCAS: 55916-52-4纯度: >99.50%
Pennogenin 3-O-beta-chacotrioside, an active component isolated from Paris polyphylla, modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1, and posesses anti-colorectal cancer activity.
- GC36963Pregnenolone monosulfateCAS: 1247-64-9纯度: >98.00%
Pregnenolone monosulfate是包括甾体酮在内的各种甾体激素的主要前体,具有多种生物学功能。
- GC37664Sorafenib (D3)CAS: 1130115-44-4纯度: >99.00%
An internal standard for the quantification of sorafenib
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC36671 | N-Benzyllinolenamide | 883715-18-2 | - | |
N-?Benzyllinolenamide 是从玛卡中得到的玛卡酰胺,为脂肪酰胺水解酶 (FAAH) 抑制剂,IC50 值为 41.8 μM。 | ||||
| GC36690 | Nampt-IN-3 | 2121591-52-2 | >99.00% | |
Nampt-IN-3 (Compound 35) 同时抑制烟酰胺磷酸核糖转移酶 (NAMPT) 和 HDAC,IC50 分别为 31 nM 和 55 nM。Nampt-IN-3 有效诱导细胞凋亡 (apoptosis) 和自噬 (autophagy),最终导致细胞死亡。 | ||||
| GC36703 | N-Benzyloleamide | 883715-21-7 | >98.00% | |
N-Benzyloleamide 是从 Lepidium meyenii (Maca) 中分离出的一种 maccamide。N-Benzyloleamide 不可逆地抑制脂肪酸酰胺水解酶 (FAAH)。N-Benzyloleamide 影响能量代谢,显示抗氧化和抗疲劳活性。 | ||||
| GC36736 | Nicodicosapent | 1269181-69-2 | >98.00% | |
Nicodicosapent 是一种脂肪酸烟酸共轭体,可以抑制固醇调节元件结合蛋白 (SREBP) 的活性,调节胆固醇代谢的蛋白质如 PCSK9,HMG-CoA reductase,ATP citrate lyase 和 NPC1L1 等的活性。 | ||||
| GC36758 | Norepinephrine hydrochloride | 329-56-6 | >99.50% / >98.00% | |
Norepinephrine hydrochloride是一种作用于α1、α2、β1等肾上腺素能受体,具有收缩血管、调节血压等药理作用的儿茶酚胺类神经递质。 | ||||
| GC36806 | Omeprazole D3 | 922731-01-9 | >98.50% | |
An internal standard for the quantification of omeprazole | ||||
| GC36821 | OSU-T315 | 2070015-22-2 | >98.00% | |
OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain). | ||||
| GC36847 | Pantoprazole sodium | 138786-67-1 | >99.50% | |
A proton pump inhibitor | ||||
| GC36848 | Pantoprazole sodium hydrate | 164579-32-2 | >98.00% | |
A proton pump inhibitor | ||||
| GC36855 | Paris saponin VII | 68124-04-9 | >98.00% / >98.50% | |
Chonglou Saponin VII (Dioscinin, Polyphyllin-VII, Paris saponin-VII), a kind of steroidal saponins from Chonglou (Rhizoma Paridis Chonglou), inhibits EMT and reduces the invasion of ovarian cancer cells via the GSK-3β/β-catenin signaling pathway. | ||||
| GC36868 | Pennogenin 3-O-beta-chacotrioside | 55916-52-4 | >99.50% | |
Pennogenin 3-O-beta-chacotrioside, an active component isolated from Paris polyphylla, modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1, and posesses anti-colorectal cancer activity. | ||||
| GC36879 | PF-04457845 | 1020315-31-4 | >99.00% | |
A selective FAAH inhibitor | ||||
| GC36928 | Pirarubicin Hydrochloride | 95343-20-7 | >98.50% | |
An anthracycline antitumor antibiotic | ||||
| GC36930 | Pitavastatin D4 | 2070009-71-9 | - | |
Pitavastatin D4是Pitavastatin氘代化合物标准品。 | ||||
| GC36963 | Pregnenolone monosulfate | 1247-64-9 | >98.00% | |
Pregnenolone monosulfate是包括甾体酮在内的各种甾体激素的主要前体,具有多种生物学功能。 | ||||
| GC37559 | Rosuvastatin D3 Sodium | 1279031-70-7 | - | |
Rosuvastatin D3钠盐是Rosuvastatin氘代化合物标准品。 | ||||
| GC37560 | Rosuvastatin D6 Calcium | - | - | |
Rosuvastatin D6钙盐是Rosuvastatin的氘代化合物标准品。 | ||||
| GC37561 | Rosuvastatin D6 Sodium | - | - | |
An internal standard for the quantification of rosuvastatin | ||||
| GC37575 | Ruxolitinib sulfate | 1092939-16-6 | - | |
A potent, selective JAK1/JAK2 inhibitor | ||||
| GC37595 | SB 242235 | 193746-75-7 | >98.50% | |
A p38α MAPK inhibitor | ||||
| GC37601 | SBE13 | 775294-82-1 | - | |
A potent Plk1 inhibitor | ||||
| GC37630 | Sevelamer | 52757-95-6 | - | |
Sevelamer HCl is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption. | ||||
| GC37646 | SKF-86002 | 72873-74-6 | >99.00% | |
An anti-inflammatory agent | ||||
| GC37664 | Sorafenib (D3) | 1130115-44-4 | >99.00% | |
An internal standard for the quantification of sorafenib | ||||
