GlpBio

FLT3

FLT3(FMS样酪氨酸激酶3)

FLT3 (FMS-like tyrosine kinase 3) is a cytokine receptor which belongs to the receptor tyrosine kinase class III and plays a role in cell survival, proliferation, and differentiation.

FLT3 相关产品(91)

  • GC10035 structure
    GC10035TG101209
    CAS: 936091-14-4
    纯度: >99.50%

    An inhibitor of JAK2, FLT3, RET, and JAK3

  • GC10914 structure
    GC10914AST 487
    CAS: 630124-46-8
    纯度: >99.00%

    A multi-kinase inhibitor

  • GC11455 structure
    GC11455Silvestrol
    CAS: 697235-38-4
    纯度: >98.00%

    Silvestrol 是一种真核翻译起始因子 4A (eIF4A) 抑制剂，从 Agave americana Linn 中分离出来。Silvestrol 诱导自噬和半胱天冬酶介导的细胞凋亡。

  • GC12058 structure
    GC12058TCS 359
    CAS: 301305-73-7
    纯度: >99.50%

    A cell-permeable FLT3 inhibitor

  • GC12064 structure
    GC12064SB1317
    CAS: 937270-47-8
    纯度: >99.50%

    A multi-kinase inhibitor

  • GC14396 structure
    GC14396Ponatinib (AP24534)
    CAS: 943319-70-8
    纯度: >99.00%

    Ponatinib (AP24534)是一种多靶点酪氨酸激酶抑制剂，可抑制Abl（IC 50 =0.37nM），PDGFRα（IC 50 =1.1nM），VEGFR2（IC 50 =1.5nM），FGFR1（IC 50 =2.2nM）和Src（IC 50 =5.4nM）的活性。

  • GC14592 structure
    GC14592KW 2449
    CAS: 1000669-72-6
    纯度: >99.50%

    A multi-kinase inhibitor

  • GC15307 structure
    GC15307SU5416
    CAS: 204005-46-9,194413-58-6
    纯度: >98.00%

    SU5416 是一种有效的小分子血管内皮生长因子受体 (VEGFR) 抑制剂。

  • GC15779 structure
    GC15779Cabozantinib (XL184, BMS-907351)
    CAS: 849217-68-1
    纯度: >99.50%

    Cabozantinib (XL184,BMS-907351) 是一种新型 MET 和 VEGFR2 抑制剂，可同时抑制转移、血管生成和肿瘤生长。

  • GC16391 structure
    GC16391Amuvatinib (MP-470, HPK 56)
    CAS: 850879-09-3
    纯度: >98.00%

    A multi-targeted RTK inhibitor

  • GC17033 structure
    GC17033Lestaurtinib
    CAS: 111358-88-4
    纯度: >98.00%

    A potent JAK2 and PRK1 kinase inhibitor

  • GC17958 structure
    GC17958Linifanib (ABT-869)
    CAS: 796967-16-3
    纯度: >98.00%

    A dual VEGFR and PDGFR family kinase inhibitor

  • GC10638 structure
    GC10638AT9283
    CAS: 896466-04-9
    纯度: >99.50%

    A broad spectrum kinase inhibitor

  • GC11057 structure
    GC11057LY2801653
    CAS: 1206799-15-6
    纯度: >98.00%

    A MET kinase inhibitor

  • GC11205 structure
    GC112055'-Fluoroindirubinoxime
    CAS: 861214-33-7
    纯度: >98.00%

    An inhibitor of FLT3 kinase

  • GC12145 structure
    GC12145ENMD-2076 L-(+)-Tartaric acid
    CAS: 1291074-87-7
    纯度: >98.50%

    ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂，对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。

  • GC12178 structure
    GC12178G-749
    CAS: 1457983-28-6
    纯度: >98.00%

    An FLT3 kinase inhibitor

  • GC12251 structure
    GC12251Tandutinib (MLN518) HCl

    FLT3 inhibitor,potent and selective

  • GC13547 structure
    GC13547Dovitinib (TKI-258, CHIR-258)
    CAS: 405169-16-6
    纯度: >98.00%

    Dovitinib (TKI-258, CHIR-258)是一种高效，具有口服活性和安全药代动力学特性的小分子多激酶抑制剂，作用于FLT3、KIT和FGFR等靶点，IC 50 值分别为1、2和8-9nM。

  • GC13848 structure
    GC13848LY2784544
    CAS: 1229236-86-5
    纯度: >99.50%

    Potent inhibitor of JAK2

  • GC14007 structure
    GC14007DCC-2036 (Rebastinib)
    CAS: 1020172-07-9
    纯度: >99.50%

    An orally bioavailable tyrosine kinase inhibitor

  • GC14582 structure
    GC14582SU5614
    CAS: 1055412-47-9

    A multi-kinase inhibitor

  • GC14906 structure
    GC14906Crenolanib (CP-868596)
    CAS: 670220-88-9
    纯度: >99.50%

    An inhibitor of PDGFRα/β and FLT3

  • GC14974 structure
    GC14974AMG 925
    CAS: 1401033-86-0
    纯度: >98.00%

    A dual inhibitor of FLT3 and Cdk4