Endogenous Metabolite
Endogenous Metabolite(内源性代谢物)
Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.
Endogenous Metabolite 相关产品(1712)
- GC60779Dimethylmalonic acidCAS: 595-46-0纯度: >98.00%
Dimethylmalonicacid是人血清中的短链二羧酸。Dimethylmalonicacid也是在肺泡呼吸中检测到的挥发性有机化合物。
- GC60793D-RibonolactoneCAS: 5336-08-3纯度: >95.00%
D-Ribonolactone是一种糖内酯，也是一种大肠杆菌β-半乳糖苷酶(β-galactosidase)的抑制剂，Ki为26mM。
- GC60859Fructosyl-lysine dihydrochlorideCAS: 96192-35-7纯度: >95.00%
Fructosyl-lysine(Fructoselysine)dihydrochloride是葡萄糖与赖氨酸通过美拉德反应生成的一种氨基糖基化产物(amadoriglycation)。Fructosyl-lysine是葡萄糖烷的前体，葡萄糖烷是一种赖氨酸-精氨酸蛋白交联物，可作为糖尿病中检测的指标。
- GC60898H-His-OH.HCl.H2OCAS: 5934-29-2纯度: >97.00%
L-Histidine monohydrochloride monohydrate (L-Histidine hydrochloride hydrate, H-His-OH.HCl.H2O), a structural analogue of the essential amino acid L-histidine, is a reversible inhibitor of protein biosynthesis which evokes disparate responses from non-tumorigenic and tumorigenic cells in culture.
- GC60948Isohomovanillic acidCAS: 1131-94-8
Isohomovanillic acid is a deaminated metabolite of catecholamines formed by the enzyme catechol-O-methyltransferase which catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine.
- GC60976L-Aspartic aicd sodiumCAS: 3792-50-5纯度: >97.00%
L-Asparticaicdsodium是一种氨基酸，被证明是一种结肠特异性药物输送的前体药物。
- GC60979L-Cysteine hydrochloride hydrateCAS: 7048-04-6纯度: >98.00%
L-cysteine Hydrochloride, also known as L-CYSTEINE or Cysteine HCL (anhydrous), is classified as a cysteine or a cysteine derivative that increases glutathione levels and is important for lung and brain function and liver detoxification.
- GC61007L-SepiapterinCAS: 17094-01-8纯度: >98.00%
L-Sepiapterin(Sepiapterin)是内皮型一氧化氮合酶(eNOS)辅因子四氢生物喋呤(BH4)的前体。L-Sepiapterin改善db/db小鼠肠系膜小动脉内皮功能障碍，诱导血管生成。L-Sepiapterin通过下调p70S6K依赖性VEGFR-2表达抑制卵巢癌细胞增殖和迁移。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC60720 | Coenzyme FO | 37333-48-5 | >99.00% | |
CoenzymeFO是一种脱氮黄素发色团，在产甲烷途径中起着重要的氢化物受体/供体作用。 | ||||
| GC60728 | Creosol | 93-51-6 | >99.50% | |
A phenolic pyrolysis product of plant biomass | ||||
| GC60734 | Cyclohexaneacetic acid | 5292-21-7 | - | |
Cyclohexaneacetic acid is a flavouring ingredient. | ||||
| GC60768 | Dibenzyl disulfide | 150-60-7 | - | |
Dibenzyldisulfide是一种内源性代谢产物。 | ||||
| GC60779 | Dimethylmalonic acid | 595-46-0 | >98.00% | |
Dimethylmalonicacid是人血清中的短链二羧酸。Dimethylmalonicacid也是在肺泡呼吸中检测到的挥发性有机化合物。 | ||||
| GC60780 | Diphenyl disulfide | 882-33-7 | >98.50% | |
Diphenyldisulfide是一种内源性代谢产物。 | ||||
| GC60784 | DL-Tryptophan | 54-12-6 | >99.50% | |
A racemic mixture of D- and L-tryptophan | ||||
| GC60793 | D-Ribonolactone | 5336-08-3 | >95.00% | |
D-Ribonolactone是一种糖内酯，也是一种大肠杆菌β-半乳糖苷酶(β-galactosidase)的抑制剂，Ki为26mM。 | ||||
| GC60819 | Ethoxyacetic acid | 627-03-2 | >97.00% | |
Ethoxyaceticacid是一种内源性代谢产物。 | ||||
| GC60859 | Fructosyl-lysine dihydrochloride | 96192-35-7 | >95.00% | |
Fructosyl-lysine(Fructoselysine)dihydrochloride是葡萄糖与赖氨酸通过美拉德反应生成的一种氨基糖基化产物(amadoriglycation)。Fructosyl-lysine是葡萄糖烷的前体，葡萄糖烷是一种赖氨酸-精氨酸蛋白交联物，可作为糖尿病中检测的指标。 | ||||
| GC60898 | H-His-OH.HCl.H2O | 5934-29-2 | >97.00% | |
L-Histidine monohydrochloride monohydrate (L-Histidine hydrochloride hydrate, H-His-OH.HCl.H2O), a structural analogue of the essential amino acid L-histidine, is a reversible inhibitor of protein biosynthesis which evokes disparate responses from non-tumorigenic and tumorigenic cells in culture. | ||||
| GC60916 | Hydroxyacetone | 116-09-6 | >97.00% | |
Hydroxyacetone是一种内源性代谢产物。 | ||||
| GC60933 | Imidazol-1-yl-acetic acid | 22884-10-2 | - | |
Imidazol-1-yl-aceticacid是一种内源性代谢产物。 | ||||
| GC60934 | Indole-3-methanamine | 22259-53-6 | >95.00% | |
Indole-3-methanamine是大麦、谷类食物的摄取生物标志物。 | ||||
| GC60942 | Isobutyryl-L-carnitine chloride | 6920-31-6 | >98.00% | |
An acylcarnitine | ||||
| GC60948 | Isohomovanillic acid | 1131-94-8 | - | |
Isohomovanillic acid is a deaminated metabolite of catecholamines formed by the enzyme catechol-O-methyltransferase which catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. | ||||
| GC60976 | L-Aspartic aicd sodium | 3792-50-5 | >97.00% | |
L-Asparticaicdsodium是一种氨基酸，被证明是一种结肠特异性药物输送的前体药物。 | ||||
| GC60979 | L-Cysteine hydrochloride hydrate | 7048-04-6 | >98.00% | |
L-cysteine Hydrochloride, also known as L-CYSTEINE or Cysteine HCL (anhydrous), is classified as a cysteine or a cysteine derivative that increases glutathione levels and is important for lung and brain function and liver detoxification. | ||||
| GC60991 | L-Homocysteine | 6027-13-0 | >98.50% | |
L-Homocysteine是一种含硫氨基酸，作为必需氨基酸蛋氨酸（Met）的中间代谢产物存在。 | ||||
| GC60999 | L-Norvaline | 6600-40-4 | >98.00% | |
An inhibitor of arginase and p70S6K1 | ||||
| GC61007 | L-Sepiapterin | 17094-01-8 | >98.00% | |
L-Sepiapterin(Sepiapterin)是内皮型一氧化氮合酶(eNOS)辅因子四氢生物喋呤(BH4)的前体。L-Sepiapterin改善db/db小鼠肠系膜小动脉内皮功能障碍，诱导血管生成。L-Sepiapterin通过下调p70S6K依赖性VEGFR-2表达抑制卵巢癌细胞增殖和迁移。 | ||||
| GC61013 | Lumisterol 3 (>90%) | 5226-01-7 | >98.00% | |
A photoisomer of previtamin D 3 | ||||
| GC61027 | m-Anisaldehyde | 591-31-1 | >99.50% | |
m-Anisaldehyde是一种内源性代谢产物。 | ||||
| GC61044 | Mesitaldehyde | 487-68-3 | >95.00% | |
Mesitaldehyde是一种内源性代谢产物。 | ||||