GlpBio

Lumisterol 3 (>90%)

目录号: GC61013纯度: >98.00%同义词: 光甾醇 3; 9β,10α-Cholesta-5,7-dien-3β-ol; Cholecalciferol EP Impurity C
A photoisomer of previtamin D3
Lumisterol 3 (>90%)
Cas No.: 5226-01-7
规格价格库存数量操作
1mg¥1,350.00现货
1
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产品描述 Description

Lumisterol 3 (L3) is a photoisomer of previtamin D3 .1 It is formed by photoisomerization of previtamin D3 in the epidermis by prolonged UVB exposure and is metabolized by the cytochrome P450 (CYP) isoform CYP11A1 in a variety of tissues to several hydroxylated metabolites, including the active metabolites 20-hydroxy L3, 24-hydroxy L3, and 20,22-dihydroxy L3.2,3

1.Slominski, A.T., Chaiprasongsuk, A., Janjetovic, Z., et al.Photoprotective droperties of vitamin D and lumisterol hydroxyderivativesCell Biochem. Biophys.78(2)165-180(2020) 2.Holick, M.F.Photosynthesis of vitamin D in the skin: Effect of environmental and life-style variablesFed. Proc.46(5)1876-1882(1987) 3.Slominski, A.T., Kim, T.-K., Hobrath, J.V., et al.Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterolsSci. Rep.7(1)11434(2017)

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
5226-01-7
同义词
光甾醇 3; 9β,10α-Cholesta-5,7-dien-3β-ol; Cholecalciferol EP Impurity C
SMILES
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])C3=CC=C(C[C@@H](O)CC4)[C@]4(C)[C@]3([H])CC1
分子式
C27H44O
分子量
384.64 g/mol
溶解性
DMSO : 2 mg/mL (5.20 mM; ultrasonic and warming and heat to 60°C)
保存条件
-80℃, protect from light, stored under nitrogen,unstable in solution, ready to use.
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol