(S)-N-Boc-L-homoserine ethyl ester is a synthetic intermediate in the synthesis of unsaturated caprolactams and monomer units for oxy-peptide nucleic acids from the starting material L-homoserine.1,2
1.Janey, J.M., Orella, C.J., Njolito, E., et al.Raney-Co mediated reductive cyclization of an α,β-unsaturated nitrileJ. Org. Chem.73(8)3212-3217(2008) 2.Kuwahara, M., Arimitsu, M., and Sisido, M.Synthesis of δ-amino acids with an ether linkage in the main chain and nucleobases on the side chain as monomer units for oxy-peptide nucleic acidsTetrahedron55(33)10067-10078(1999)