GlpBio

p38

p38 (p38 mitogen-activated protein kinases) are serine/threonine kinases that activated by environmental stress and proinflammatory cydtokines. They mediates cell growth, differentiation, transcrption and development.

p38 相关产品(100)

  • GC15814 structure
    GC15814Pamapimod (R-1503, Ro4402257)
    CAS: 449811-01-2
    纯度: >99.50%

    An orally bioavailable inhibitor of p38α MAP kinase

  • GC16019 structure
    GC16019SB 202474
    CAS: 172747-50-1

    A negative control for SB 202190 and SB 203580

  • GC16997 structure
    GC16997BMS-582949
    CAS: 623152-17-0

    A p38α MAP kinase inhibitor

  • GC17725 structure
    GC17725SKF 86002 dihydrochloride
    CAS: 116339-68-5

    An anti-inflammatory agent

  • GC17957 structure
    GC17957SX 011
    CAS: 309913-42-6

    p38α inhibitor

  • GC18273 structure
    GC18273SB 202190 (hydrochloride)
    CAS: 350228-36-3
    纯度: >99.50%

    A potent and selective p38 MAP kinase inhibitor

  • GC18602 structure
    GC18602p38 MAPK Inhibitor IV
    CAS: 1638-41-1
    纯度: >98.00%

    An inhibitor of p38 MAP kinases

  • GC19019 structure
    GC19019Acumapimod
    CAS: 836683-15-9
    纯度: >99.00%

    An inhibitor of p38α MAPK

  • GC19304 structure
    GC19304R1487 Hydrochloride
    CAS: 449808-64-4
    纯度: >98.50%

    An inhibitor of p38α MAPK

  • GC19325 structure
    GC19325SD 0006
    CAS: 271576-80-8
    纯度: >98.50%

    An inhibitor of p38α MAPK

  • GC19366 structure
    GC19366UM-164
    CAS: 903564-48-7
    纯度: >98.50%

    An inhibitor of Src and p38 MAPK kinases

  • GC20007 structure
    GC20007Ginsenoside CK
    CAS: 39262-14-1
    纯度: >98.00%

    Ginsenoside CK，一种由主要人参皂苷化合物转化而来的次级人参皂苷，比其母体人参皂苷具有更高的生物利用度和溶解性，具有极其重要的意义。

  • GC30158 structure
    GC30158p38-α MAPK-IN-1
    CAS: 443913-15-3
    纯度: >99.50%

    p38-α MAPK-IN-1 is an inhibitor of p38-α, with IC50 value of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay.

  • GC30609 structure
    GC30609p38 MAPK-IN-2
    CAS: 635725-16-5

    p38MAPK-IN-2是一种p38kinase的抑制剂。

  • GC30646 structure
    GC30646Skatole(3-Methylindole)
    CAS: 83-34-1
    纯度: >99.50%

    Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.

  • GC30676 structure
    GC30676MAPK13-IN-1
    CAS: 229002-10-2
    纯度: >98.00%

    MPAK13-IN-1是MAPK13(p38δ)的一个抑制剂，其IC50值为620nM。

  • GC31058 structure
    GC31058FR 167653 free base
    CAS: 158876-65-4

    FR-167653是一种选择性的p38MAPK抑制剂。

  • GC31697 structure
    GC31697Dilmapimod (SB-681323)
    CAS: 444606-18-2
    纯度: >99.50%

    Dilmapimod (SB-681323,GW 681323) is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease.

  • GC31924 structure
    GC31924AZD7624
    CAS: 1095004-78-6
    纯度: >98.00%

    AZD7624是一种可吸入的p38抑制剂，具有高效的抗炎活性。

  • GC31988 structure
    GC31988p38α inhibitor 1
    CAS: 1034189-82-6
    纯度: >98.50%

    p38αinhibitor1是p38α的抑制剂，来自专利WO2008076265A1。

  • GC32209 structure
    GC32209ITX5061
    CAS: 1252679-52-9
    纯度: >98.00%

    ITX5061是一个II型p38MAPK抑制剂，也是清道夫受体B1(SR-B1)的拮抗剂。

  • GC32411 structure
    GC32411FR 167653 (FR 167653 sulfate)
    CAS: 158876-66-5

    FR 167653 (FR 167653硫酸盐) (FR 167653 (FR 167653硫酸盐))，一种具有口服活性和选择性的p38 MAPK抑制剂，是TNF-α的强效抑制剂；和 IL-1β；通过特异性抑制 p38 MAPK 活性产生。

  • GC33008 structure
    GC33008p38 MAPK-IN-1
    CAS: 1006378-90-0
    纯度: >99.50%

    p38MAPK-IN-1是p38MAPK新型高效选择性抑制剂,IC50值68nM。

  • GC33229 structure
    GC33229SJFα
    CAS: 2254609-27-1

    SJFα是一种含13个原子连接桥的PROTAC。SJFα降解p38α，DC50为7.16nM，但降解p38δ效果较差(DC50=299nM)，且在浓度高达2.5μM时也不会降解其他p38亚型(β和γ)。