JNK(c-Jun N-末端激酶)

JNK (c-Jun N-terminal kinase) is a group of kinases belong to the mitogen-activated protein kinase family and also play a role in T cell differentiation and the cellular apoptosis pathway.

Products for JNK

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Cat.No. 产品名称 Information
GC16652 SR 3576 A JNK3 inhibitor
GC30864 SR-3306 SR-3306是一种有效的可渗透脑的选择性JNK抑制剂。
GC11542 SU 3327

2-氨基-5-[(5-硝基-2-噻唑基)硫代]-1,3,4-噻二唑
A JNK1 inhibitor with antidiabetic and antibiotic activity
GC25982 Tanzisertib(CC-930)

JNK-930, JNKI-1
Tanzisertib (CC-930, JNK-930, JNKI-1) is kinetically competitive with ATP in the JNK-dependent phosphorylation of the protein substrate c-Jun and potent against all isoforms of JNK (Ki(JNK1) = 44 ± 3 nM, IC50(JNK1) = 61 nM, Ki(JNK2) = 6.2 ± 0.6 nM, IC50(JNK2) = 5 nM, IC50(JNK3) = 5 nM) and selective against MAP kinases ERK1 and p38a with IC50 of 0.48 and 3.4 μM respectively.
GC11488 TCS JNK 5a

JNK Inhibitor IX
A selective inhibitor of JNK2 and JNK3
GC17282 TCS JNK 6o

JNK Inhibitor VIII
A JNK inhibitor
GC31647 Tomatidine

番茄碱
A steroidal alkaloid with diverse biological activities
GC45064 Tomatidine (hydrochloride)

盐酸番茄碱
A steroidal alkaloid with diverse biological activities
GC38679 Urolithin B

尿石素B
A metabolite of ellagic acid
GC38053 WHI-P258 A negative control for JAK3 inhibition