Calcium Channel(钙离子通道)

Calcium channel is an ion channel that selectively permeable to calcium ions. It serves vital functions in cellular signal transduction.

Products for Calcium Channel

Cat.No. 产品名称 Information
GC10447 Isradipine (Dynacirc)
伊拉地平,PN 200-110
An L-type calcium channel blocker
GC12714 Gabapentin
加巴喷丁
An approved antiepileptic drug
GC14289 Fasudil (HA-1077) HCl
盐酸法舒地尔; HA-1077 Hydrochloride; AT-877 Hydrochloride
Fasudil (HA-1077) HCl（法舒地尔；HA-1077；AT877）是一种非特异性RhoA/ROCK抑制剂，对ROCK1的K_i为0.33μM，IC₅₀为0.158μM，对ROCK2和PKA、PKC、PKG的IC₅₀分别为4.58μM、12.30μM、1.650μM。
GC11735 Zonisamide
唑尼沙胺; AD 810; CI 912
A broad-spectrum sulfonamide antiepileptic agent
GC13882 Ranolazine 2HCl
盐酸雷诺嗪; CVT 303 dihydrochloride; RS 43285
A piperazine derivative with cardioprotective activity
GC12312 Cilnidipine
西尼地平; FRC-8653
An L- and N-type calcium channel blocker
GC13016 Safinamide
沙芬酰胺; FCE 26743; EMD 1195686
Safinamide 是一种强效、选择性和可逆的单胺氧化酶 B (MAO-B) 抑制剂 (IC50=0.098 μM)，优于 MAO-A (IC50=580 μM)。
GC14417 NNC 55-0396
NNC 55-0396 dihydrochloride
A selective T-type calcium channel inhibitor
GC10218 Mibefradil dihydrochloride
盐酸米贝地尔; Ro 40-5967 dihydrochloride
Mibefradil dihydrochloride是一种钙通道阻断剂，可以阻断T型和L型钙通道，Mibefradil dihydrochloride对T型和L型钙电流的IC₅₀分别为0.7μM和2μM。
GC12268 Mibefradil
米贝地尔,Ro 40-5967
Mibefradil是一种钙通道阻断剂，可以阻断T型和L型钙通道，Mibefradil对T型和L型钙电流的IC₅₀分别为0.7μM和2μM。
GC16149 Topiramate
托吡酯; McN 4853; RWJ 17021
Topiramate是一种口服有效的磺胺衍生单糖，具有广谱抗癫痫活性。
GN10715 Catharanthine Tartrate
酒石酸长春质碱; (+)-3,4-Didehydrocoronaridine Tartrate
An indole alkaloid with diverse biological activities
GN10612 (+)- Praeruptorin C
白花前胡丙素
(+)- Praeruptorin C 是前胡的主要生物活性成分（也称为白花前胡）。
GN10517 Ginsenoside Rf
人参皂苷 Rf; Panaxoside Rf
A natural steroid glycoside with diverse effects
GN10445 (±)-Praeruptorin A
(±)-白花前胡甲素
(±)-Praeruptorin A是ciskhellactone（CKL）的二酯化产物，是紫草根中的主要活性成分，具有显著的抗高血压作用，通常通过作为钙通道阻滞剂发挥作用。
GN10446 Tetrandrine
汉防己甲素; NSC-77037; d-Tetrandrine
An alkaloid with diverse biological activities
GN10549 Ginsenoside Rd
人参皂苷 Rd; Gypenoside VIII
A natural steroid glycoside with diverse effects
GN10756 Ophiopogonin D
麦冬皂苷D
A steroid glycoside with diverse biological activities
GN10069 Ginsenoside Ro
人参皂苷 Ro; Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V
A non-steroid glycoside with diverse biological activities
GN10791 Catharanthine
长春质碱; (+)-3,4-Didehydrocoronaridine
An indole alkaloid with diverse biological activities
GA10299 H-Phe-OH
L-苯丙氨酸; (S)-2-Amino-3-phenylpropionic acid
H-Phe-OH ((S)-2-Amino-3-phenylpropionic acid) 是一种从大肠杆菌中分离出来的必需氨基酸。