Apoptosis
Apoptosis(凋亡)
FKBP (FK506-binding protein) is one of two major immunophilins and most of FKBP family members bind FK506 and show peptidylprolyl cis/trans isomerase (PPIase) activity. Small size FKBP family members contain only FK506-binding domain, while FKBPs with large molecular weights possess extra domains such as tetratricopeptide repeat domains, calmodulin binding and transmembrane motifs. FKBPs are involved in several biochemical processes including protein folding, receptor signaling, protein trafficking and transcription. FKBP family proteins play important functional roles in the T-cell activation, when complexed with their ligands.
FK506-binding proteins 1a and 1b (FKBP1a/1b) are immunophilin proteins that bind the immunosuppressant agent FK506 and AY 22989. FKBP12 is a ubiquitous abundant protein that acts as a receptor for FK506, binds tightly to intracellular calcium release channels and to the transforming growth factor β (TGF-β) type I receptor.
Apoptosis 相关产品(777)
- GC48839Nifuroxazide-d4CAS: 1188487-83-3纯度: >99.00%
An internal standard for the quantification of nifuroxazide
- GC48848Albendazole-d7CAS: 1287076-43-0纯度: >99.00%
An internal standard for the quantification of albendazole
- GC48907Metaxalone-d6CAS: 1189944-95-3纯度: >99.00%
An internal standard for the quantification of metaxalone
- GC49042Benastatin ACAS: 138968-85-1纯度: >90.00%
A bacterial metabolite with diverse biological activities
- GC49096Cobaltic Protoporphyrin IX (chloride)CAS: 102601-60-5纯度: >95.00% / >98.00%
Cobaltic Protoporphyrin IX (chloride)是一种高价钴配位卟啉化合物。Cobaltic Protoporphyrin IX (chloride)通过上调HO-1的抗氧化、抗炎和细胞保护功能，有助于减轻免疫相关的肾脏损伤。
- GC49137Triclabendazole-13C-d3CAS: 2938916-53-9纯度: >99.00%
An internal standard for the quantification of triclabendazole
- GC492232-deoxy-D-Glucose-13C6纯度: >95.00%
An internal standard for the quantification of 2-deoxy-D-glucose
- GC49251Oxaliplatin-d10CAS: 1132819-16-9纯度: >99.00%
An internal standard for the quantification of oxaliplatin
- GC49268(+)-δ-CadineneCAS: 483-76-1纯度: >95.00%
A sesquiterpene with antimicrobial and anticancer activities
- GC49270Nicotinamide-d4CAS: 347841-88-7纯度: >99.00%
An internal standard for the quantification of nicotinamide
- GC49308UngeremineCAS: 2121-12-2纯度: >98.00%
A betaine-type alkaloid with diverse biological activities
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC48676 | Monascuspiloin | 1011244-19-1 | >85.00% | |
A fungal metabolite with anticancer activity | ||||
| GC48689 | SBP-7455 | 1884222-74-5 | >98.00% | |
A dual inhibitor of ULK1 and ULK2 | ||||
| GC48839 | Nifuroxazide-d4 | 1188487-83-3 | >99.00% | |
An internal standard for the quantification of nifuroxazide | ||||
| GC48848 | Albendazole-d7 | 1287076-43-0 | >99.00% | |
An internal standard for the quantification of albendazole | ||||
| GC48907 | Metaxalone-d6 | 1189944-95-3 | >99.00% | |
An internal standard for the quantification of metaxalone | ||||
| GC48971 | AZD 1152 (hydrochloride) | 722543-50-2 | >95.00% | |
A prodrug for a potent Aurora B inhibitor | ||||
| GC48974 | Ac-VEID-AMC (ammonium acetate salt) | - | >95.00% | |
A caspase-6 fluorogenic substrate | ||||
| GC49015 | Phenethyl isothiocyanate | 2257-09-2 | >99.00% | |
An isothiocyanate with anticancer activity | ||||
| GC49042 | Benastatin A | 138968-85-1 | >90.00% | |
A bacterial metabolite with diverse biological activities | ||||
| GC49080 | CAY10786 | 1239987-91-7 | >98.00% | |
A GPR52 antagonist | ||||
| GC49084 | PHY34 | 2130033-55-3 | >98.00% | |
An inhibitor of late-stage autophagy | ||||
| GC49096 | Cobaltic Protoporphyrin IX (chloride) | 102601-60-5 | >95.00% / >98.00% | |
Cobaltic Protoporphyrin IX (chloride)是一种高价钴配位卟啉化合物。Cobaltic Protoporphyrin IX (chloride)通过上调HO-1的抗氧化、抗炎和细胞保护功能，有助于减轻免疫相关的肾脏损伤。 | ||||
| GC49130 | Hydroxy Celecoxib | 170571-00-3 | >95.00% | |
An inactive metabolite of celecoxib | ||||
| GC49137 | Triclabendazole-13C-d3 | 2938916-53-9 | >99.00% | |
An internal standard for the quantification of triclabendazole | ||||
| GC49152 | Celecoxib Carboxylic Acid | 170571-01-4 | >95.00% | |
An inactive metabolite of celecoxib | ||||
| GC49168 | Visnagin | 82-57-5 | >98.00% | |
A furanochromone with diverse biological activities | ||||
| GC49177 | Loliolide | 5989-02-6 | >98.00% | |
Loliolide是一种具有多种生物活性的单萜内酯。 | ||||
| GC49221 | QLT0267 | 866409-68-9 | >98.00% | |
An ILK inhibitor | ||||
| GC49223 | 2-deoxy-D-Glucose-13C6 | - | >95.00% | |
An internal standard for the quantification of 2-deoxy-D-glucose | ||||
| GC49251 | Oxaliplatin-d10 | 1132819-16-9 | >99.00% | |
An internal standard for the quantification of oxaliplatin | ||||
| GC49259 | Antagonist G (trifluoroacetate salt) | - | >98.00% | |
A neuropeptide antagonist | ||||
| GC49268 | (+)-δ-Cadinene | 483-76-1 | >95.00% | |
A sesquiterpene with antimicrobial and anticancer activities | ||||
| GC49270 | Nicotinamide-d4 | 347841-88-7 | >99.00% | |
An internal standard for the quantification of nicotinamide | ||||
| GC49308 | Ungeremine | 2121-12-2 | >98.00% | |
A betaine-type alkaloid with diverse biological activities | ||||