GlpBio

5-HT Receptor

5-HT Receptor(5-羟色胺受体)

5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.

5-HT Receptor 相关产品(481)

  • GC39724 structure
    GC39724Quetiapine D4 hemifumarate
    CAS: 1217310-65-0

    Quetiapine D4 hemifumarate 是 Quetiapine hemifumarate 的氘代物。Quetiapine 是一种 5-HT 受体激动剂，也是一种多巴胺受体 (dopamine receptor) 拮抗剂。具有抗抑郁和抗焦虑作用。

  • GC39748 structure
    GC39748Facinicline hydrochloride
    CAS: 677305-02-1
    纯度: >99.50%

    Facinicline hydrochloride (RG3487 hydrochloride) 是具有口服活性的烟碱 α7 receptor 部分激动剂，对人nAChR 的 Ki 值为 6 nM。Facinicline hydrochloride (RG3487 hydrochloride) 可改善啮齿类动物的认知和感觉运动门控。Facinicline hydrochloride (RG3487 hydrochloride) 对5-HT3 受体 (拮抗剂)的Ki 值为 1.2 nM。

  • GC43353 structure
    GC43353Cyproheptadine (hydrochloride hydrate)
    CAS: 41354-29-4
    纯度: >99.00%

    An antihistamine with antiserotonergic and anticholinergic activities

  • GC43926 structure
    GC43926Jatrorrhizine (chloride)
    CAS: 6681-15-8
    纯度: >98.00%

    An alkaloid with diverse biological activities

  • GC43999 structure
    GC43999Ketanserin (tartrate)
    CAS: 83846-83-7
    纯度: >99.50%

    A potent 5-HT 2 receptor antagonist

  • GC44875 structure
    GC44875SB-242084 (hydrochloride)
    CAS: 1049747-87-6
    纯度: >98.00%

    Specific antagonist of 5-HT 2C

  • GC44978 structure
    GC44978Syk Inhibitor II
    CAS: 726695-51-8
    纯度: >98.00%

    A selective blocker of spleen tyrosine kinase activity

  • GC45157 structure
    GC45157WAY-161503
    CAS: 75704-24-4
    纯度: >99.00%

    A 5-HT 2C receptor agonist

  • GC45791 structure
    GC45791PF-04995274
    CAS: 1331782-27-4
    纯度: >99.00%

    A partial 5-HT 4 agonist

  • GC46007 structure
    GC46007Cariprazine-d6
    CAS: 1308278-67-2
    纯度: >99.00%

    An internal standard for the quantification of cariprazine

  • GC48255 structure
    GC48255Vortioxetine-d8
    CAS: 2140316-62-5
    纯度: >99.00%

    An internal standard for the quantification of vortioxetine

  • GC50006 structure
    GC50006RU 24969 hemisuccinate
    CAS: 66611-27-6

    A 5-HT 1A and 5-HT 1B receptor agonist

  • GC50007 structure
    GC50007RS 102221 hydrochloride
    CAS: 187397-18-8

    A 5-HT 2C receptor antagonist

  • GC50014 structure
    GC50014SB 215505
    CAS: 162100-15-4

    SB 215505 是一种有效的亚型选择性 5-HT2B 受体拮抗剂，对 5-HT2B、5-HT2A、5-HT2C 的 pKi 值分别为 8.3、6.77、7.66。

  • GC50027 structure
    GC50027Xaliproden hydrochloride
    CAS: 90494-79-4
    纯度: >99.00%

    A 5-HT 1A receptor agonist

  • GC50031 structure
    GC50031Tandospirone hydrochloride
    CAS: 99095-10-0

    Tandospirone (SM-3997) hydrochloride 是一种有效的选择性 5-HT1A 受体部分激动剂，Ki 为 27 nM。

  • GC50033 structure
    GC50033RS 127445 hydrochloride
    CAS: 199864-86-3
    纯度: >99.50%

    A 5-HT 2B receptor antagonist

  • GC50084 structure
    GC50084Eplivanserin hemifumarate
    CAS: 130580-02-8
    纯度: >98.00%

    Eplivanserin (SR-46349) hemifumarate 是一种有效、选择性和口服活性的 5-HT2A 受体拮抗剂，在大鼠皮质膜中的 IC50 为 5.8 nM，Kd 为 1.14 nM。

  • GC50213 structure
    GC50213WAY 181187 oxalate
    CAS: 1883548-85-3

    WAY-181187 (SAX-187) oxalate 是一种有效的选择性全 5-HT6 受体激动剂，Ki 为 2.2 nM，EC50 为 6.6 nM。

  • GC50258 structure
    GC50258(R)-Citalopram oxalate
    CAS: 219861-53-7

    Enantiomer of escitalopram oxalate

  • GC50564 structure
    GC50564PRX 07034
    CAS: 903580-39-2
    纯度: >98.00%

    PRX 07034 是一种高度选择性和有效的 5-HT6 受体拮抗剂，Ki = 4-8 nM，IC50 为 19 nM。

  • GC50668 structure
    GC50668PF 04479745
    CAS: 1065110-43-1
    纯度: >98.00%

    PF 04479745 是一种有效的选择性 5-HT2C 受体激动剂（EC50:10 nM，ki:15 nM）。 PF 04479745 可用于高血压等心血管疾病的研究。

  • GC60017 structure
    GC600172'-O-Methylisoliquiritigenin
    CAS: 51828-10-5
    纯度: >98.00%

    2'-O-Methylisoliquiritigenin可从Arachis中分离得到，可上调5-HT、NE、DA和GABA信号通路，对NE通路影响不大。

  • GC60028 structure
    GC600285-HT1A modulator 2 hydrochloride
    CAS: 3880-76-0
    纯度: >98.00%

    5-HT1Amodulator2hydrochloride是8-OH-DPAT的一种衍生物，5-HT1Amodulator2hydrochloride是5-HT1A的调节剂，与5-HT1A结合的Ki值为53nM。