Dopamine Receptor
Dopamine Receptor(多巴胺受体)
Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.
Dopamine Receptor 相关产品(289)
- GC17047Threo-methylphenidate hydrochlorideCAS: 298-59-9纯度: >98.00%
盐酸苏哌甲酯(Threo-methylphenidate hydrochloride)是一种儿茶酚胺再摄取抑制剂,抑制多巴胺转运蛋白(DAT)和去甲肾上腺素转运蛋白(NET)。
- GC17192Quinelorane hydrochlorideCAS: 97548-97-5
Quinelorane hydrochloride (LY163502) 是一种有效的多巴胺 D3/D2 受体激动剂。
- GC17527(+)-Dihydrexidine hydrochlorideCAS: 158704-02-0纯度: >98.50%
(+)-Dihydrexidine hydrochloride ((+)-DAR-0100 hydrochloride) 是一种多巴胺 D1 受体激动剂，EC50 为 72± 21 nM。
- GC17729SKF38393 HClCAS: 62717-42-4纯度: >99.00%
SKF38393 HCl 是一种多巴胺 D1 受体 (D1DR) 的选择性激动剂，IC50 为 110 nM。
- GC17877(-)-Quinpirole hydrochlorideCAS: 85798-08-9纯度: >99.50% / >99.00%
(-)-Quinpirole hydrochloride ((-)-LY 171555) 是一种多巴胺 D2/D3 受体的高亲和力激动剂。
- GC30280Chlorpromazine D6 hydrochlorideCAS: 1228182-46-4纯度: >99.50%
Chlorpromazine D6 hydrochloride是 Chlorpromazine 的氘代物，可被用于 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。
- GC30396Piribedil D8 (ET-495 D8)CAS: 1398044-45-5
Piribedil D8 (ET-495 D8) (ET-495 D8) 是氘标记的 Piribedil，它是一种抗帕金森病药物。
- GC30772Dopamine serotonin antagonist-1CAS: 1977-07-7
Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.
- GC30790Triflupromazine hydrochlorideCAS: 1098-60-8纯度: >99.50%
A phenothiazine with diverse biological activities
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC16992 | SCH 39166 hydrobromide | 1227675-51-5 | - | |
A dopamine D 1 receptor antagonist | ||||
| GC17047 | Threo-methylphenidate hydrochloride | 298-59-9 | >98.00% | |
盐酸苏哌甲酯(Threo-methylphenidate hydrochloride)是一种儿茶酚胺再摄取抑制剂,抑制多巴胺转运蛋白(DAT)和去甲肾上腺素转运蛋白(NET)。 | ||||
| GC17075 | NPEC-caged-dopamine | 1257326-23-0 | >99.00% | |
Dopamine receptor agonist | ||||
| GC17192 | Quinelorane hydrochloride | 97548-97-5 | - | |
Quinelorane hydrochloride (LY163502) 是一种有效的多巴胺 D3/D2 受体激动剂。 | ||||
| GC17238 | OSU 6162 hydrochloride | 156907-84-5 | - | |
Dopamine stabilizer | ||||
| GC17527 | (+)-Dihydrexidine hydrochloride | 158704-02-0 | >98.50% | |
(+)-Dihydrexidine hydrochloride ((+)-DAR-0100 hydrochloride) 是一种多巴胺 D1 受体激动剂，EC50 为 72± 21 nM。 | ||||
| GC17593 | Lurasidone HCl | 367514-88-3 | >98.00% | |
An atypical antipsychotic | ||||
| GC17634 | PD 168077 maleate | 630117-19-0 | >98.50% | |
A dopamine D 4 receptor agonist | ||||
| GC17656 | Chlorprothixene (hydrochloride) | 6469-93-8 | >98.00% | |
A dopamine D 2 receptor antagonist | ||||
| GC17729 | SKF38393 HCl | 62717-42-4 | >99.00% | |
SKF38393 HCl 是一种多巴胺 D1 受体 (D1DR) 的选择性激动剂，IC50 为 110 nM。 | ||||
| GC17841 | JHW 007 hydrochloride | 202645-74-7 | - | |
Dopamine uptake inhibitor | ||||
| GC17877 | (-)-Quinpirole hydrochloride | 85798-08-9 | >99.50% / >99.00% | |
(-)-Quinpirole hydrochloride ((-)-LY 171555) 是一种多巴胺 D2/D3 受体的高亲和力激动剂。 | ||||
| GC17890 | LE 300 | 274694-98-3 | - | |
A dopamine D 1 -like and 5-HT 2A receptor antagonist | ||||
| GC18068 | NGB 2904 | 189060-98-8 | >99.00% / >98.00% | |
A selective D 3 antagonist | ||||
| GC19176 | GSK163090 | 844903-58-8 | >99.50% | |
GSK163090 是一种有效的、选择性的和具有口服活性的 5-HT1A/1B/1D 受体拮抗剂，pKi 值分别为 9.4/8.5/9.7。 | ||||
| GC19499 | A-381393 | 726174-00-1 | >99.50% | |
A-381393 是一种有效的、选择性的脑穿透多巴胺 D4 受体拮抗剂，对人多巴胺 D4.4、D4.2 和 D4.7 受体的 Kis 分别为 1.5、1.9 和 1.6 nM，比选择性高 2700 倍以上D1、D2、D3 和 D5 多巴胺受体。 | ||||
| GC30241 | GSK598809 | 863680-45-9 | >99.50% | |
GSK598809是多巴胺D3受体(DRD3)的选择性拮抗剂，其pKi值为8.9。 | ||||
| GC30280 | Chlorpromazine D6 hydrochloride | 1228182-46-4 | >99.50% | |
Chlorpromazine D6 hydrochloride是 Chlorpromazine 的氘代物，可被用于 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。 | ||||
| GC30375 | Clomipramine D3 | 136765-29-2 | - | |
An Analytical Reference Standard | ||||
| GC30396 | Piribedil D8 (ET-495 D8) | 1398044-45-5 | - | |
Piribedil D8 (ET-495 D8) (ET-495 D8) 是氘标记的 Piribedil，它是一种抗帕金森病药物。 | ||||
| GC30772 | Dopamine serotonin antagonist-1 | 1977-07-7 | - | |
Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. | ||||
| GC30787 | Sertindole (Lu 23-174) | 106516-24-9 | >99.50% | |
An atypical antipsychotic | ||||
| GC30790 | Triflupromazine hydrochloride | 1098-60-8 | >99.50% | |
A phenothiazine with diverse biological activities | ||||
| GC30797 | lumateperone Tosylate (ITI-007) | 1187020-80-9 | >99.00% | |
An atypical antipsychotic | ||||