GlpBio

Dopamine serotonin antagonist-1

目录号: GC30772纯度: >98%同义词: 氯氮平杂质,Deschloroclozapine
COASDSData Sheet
Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.
Dopamine serotonin antagonist-1
Cas No.: 1977-07-7
规格价格库存数量操作
10mg¥982.00现货
1
50mg¥3,481.00现货
1
100mg¥5,220.00现货
1
10mM (in 1mL DMSO)¥971.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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产品描述 Description

Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.

[1] Hu F, et al. Eur J Med Chem. 2021 Mar 5;213:113047.

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
1977-07-7
同义词
氯氮平杂质,Deschloroclozapine
SMILES
CN1CCN(C2=NC3=CC=CC=C3NC4=CC=CC=C42)CC1
分子式
C18H20N4
分子量
292.38 g/mol
溶解性
DMSO : ≥ 83.3 mg/mL (284.90 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol