GlpBio

Dopamine Receptor

Dopamine Receptor(多巴胺受体)

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

Dopamine Receptor 相关产品(289)

  • GC30824 structure
    GC30824Veralipride ((±)-Veralipride)
    CAS: 66644-81-3
    纯度: >99.50%

    Veralipride ((±)-Veralipride) 是一种 D2 受体拮抗剂。

  • GC30840 structure
    GC30840Quinagolide hydrochloride (CV205-502 hydrochloride)
    CAS: 94424-50-7

    Quinagolide hydrochloride (CV205-502 hydrochloride) 是一种选择性多巴胺 D2 受体激动剂，也是一种催乳素抑制剂。

  • GC30848 structure
    GC30848(+)-PD 128907 hydrochloride
    CAS: 300576-59-4
    纯度: >98.00%

    A potent D 3 receptor agonist

  • GC30854 structure
    GC30854Pridopidine (ACR16)
    CAS: 346688-38-8
    纯度: >99.50%

    Pridopidine (ACR16, ASP2314, FR310826) , a dopamine (DA) stabilizer, acts as an antagonist against sigma 1 receptor (S1R) and dopamine D2 receptor (D2R).

  • GC30871 structure
    GC30871Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride)
    CAS: 28094-15-7
    纯度: >98.00% / >97.00%

    Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride)（6-OHDA）是神经递质多巴胺的拮抗剂。

  • GC30904 structure
    GC30904Molindone hydrochloride (EN-1733A)
    CAS: 15622-65-8
    纯度: >99.50%

    A dopamine receptor antagonist

  • GC30926 structure
    GC30926Lurasidone (SM-13496)
    CAS: 367514-87-2
    纯度: >99.50%

    An atypical antipsychotic

  • GC30944 structure
    GC30944Sultopride hydrochloride (LIN-1418 hydrochloride)
    CAS: 23694-17-9
    纯度: >98.00%

    Sultopride hydrochloride (LIN-1418 hydrochloride) (LIN-1418 hydrochloride) 是多巴胺 D2 受体的选择性拮抗剂。

  • GC30974 structure
    GC30974Promazine hydrochloride
    CAS: 53-60-1
    纯度: >99.00%

    Promazine (Romtiazin, Sinophenin) is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors with antipsychotic effects.

  • GC30975 structure
    GC30975Tiapride hydrochloride
    CAS: 51012-33-0
    纯度: >99.00%

    Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain and is used to treat a variety of neurological and psychiatric disorders.

  • GC30980 structure
    GC30980Pardoprunox hydrochloride (SLV-308 hydrochloride)
    CAS: 269718-83-4
    纯度: >98.00%

    A dopamine D 2 and D 3 receptor partial agonist and 5-HT 1A agonist

  • GC30995 structure
    GC30995CGP 25454A
    CAS: 104391-26-6
    纯度: >99.00%

    CGP25454A是一个新颖和选择性的突触前多巴胺自受体拮抗剂。

  • GC31015 structure
    GC31015NRA-0160
    CAS: 204718-47-8

    NRA-0160是一种选择性的dopamineD4receptor拮抗剂，Ki值为0.48nM；同时对dopamineD2receptor，D3receptor，大鼠5-HT2Areceptor和α1adrenoceptor分别具有不同程度的亲和度，Ki值分别为>10000nM，39nM，180nM和237nM。

  • GC31018 structure
    GC31018NEO 376 (SPI-376)
    CAS: 496921-73-4

    NEO 376 (SPI-376) 是 5-HT1 受体、GABA 受体和多巴胺受体的选择性调节剂，具有抗精神病活性。

  • GC31037 structure
    GC31037Clocapramine (Clocarpramine)
    CAS: 47739-98-0

    Clocapramine是多巴胺D2和5-HT2A受体拮抗剂。

  • GC31047 structure
    GC31047Bromopride
    CAS: 4093-35-0

    A dopamine D 2 receptor antagonist

  • GC31055 structure
    GC31055Abaperidone
    CAS: 183849-43-6

    Abaperidone是一种有效的5-HT2A受体和多巴胺D2受体拮抗剂，IC50分别为6.2和17nM。

  • GC31069 structure
    GC31069Pardoprunox (SLV-308)
    CAS: 269718-84-5

    Pardoprunox hydrochloride (DU-126891, SME-308) is a potent but partial dopamine D2 receptor agonist with pEC50 of 8.0, and a partial agonist in the induction of [35S]GTPγS binding with pEC50 of 9.2 and a serotonin 5-HT1A receptor agonist, with pEC50 of 6.3, respectively.

  • GC31111 structure
    GC31111NMI 8739
    CAS: 129024-87-9

    A conjugate of DHA and dopamine

  • GC31173 structure
    GC31173Ocaperidone (R79598)
    CAS: 129029-23-8
    纯度: >99.50%

    Ocaperidone (R79598) 是一种有效的抗精神病药，作为有效的 5-HT2 和多巴胺 D2 拮抗剂和 5-HT1A 激动剂，对 5-HT2 的 Kis 分别为 0.14 nM、0.46 nM、0.75 nM、1.6 nM 和 5.4 nM 、a1-肾上腺素受体、多巴胺 D2、组胺 H1 和 a2-肾上腺素受体，h5-HT1A 的 pEC50 和 pKi 分别为 7.60 和 8.08。

  • GC31183 structure
    GC31183Piperidine-MO-1
    CAS: 871351-61-0

    Piperidine-MO-1是来自专利WO/2005/121087A1化合物实例2的多巴胺受体(dopaminereceptor)调节剂，在大鼠纹状体中增加DOPAC的ED50值为68μmol/kg。

  • GC31188 structure
    GC31188Sultopride (LIN-1418)
    CAS: 53583-79-2

    Sultopride (LIN-1418) (LIN-1418) 是多巴胺 D2 受体的选择性拮抗剂。

  • GC31214 structure
    GC31214A-437203 (Lu201640)
    CAS: 220519-06-2

    A-437203 (Lu201640) 是一种选择性 D3 受体拮抗剂，对 D2、D3 和 D4 受体的 Ki 分别为 71、1.6 和 6220 nM。

  • GC31225 structure
    GC31225PF-592379
    CAS: 710655-15-5

    PF-592379是一种有效的多巴胺D3受体激动剂，EC50为21nM。