Cardiovascular(心血管)

Cardiovascular

The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment. read more

Products for Cardiovascular

Cat.No. 产品名称 Information
GC18635 18-hydroxy-11-deoxy Corticosterone
18-Hydroxydeoxycorticosterone, 18-OH-DOC
A mineralocorticoid
GC18634 11-deoxy Prostaglandin E1
11脱氧前列腺素E1
A selective EP₂ receptor agonist
GC18616 MMP-8 Inhibitor I
Matrix Metalloproteinase-8 Inhibitor I
MMP-8 Inhibitor I是一种强效的基质金属蛋白酶-8（MMP-8）抑制剂，但口服生物利用度较低。
GC18522 Phosphatidylserines (sodium salt)
L-α-磷脂酰丝氨酸（钠盐）,L-α-Phosphatidylserine
A mixture of phosphatidylserines isolated from soy
GC18474 Acetyldigitoxin
乙酰洋地黄毒甙; Digitoxin 3'''-Acetate
An Na⁺/K⁺ ATPase inhibitor
GC18455 Digoxigenin Monodigitoxoside
地高辛杂质D
A Na⁺/K⁺-ATPase inhibitor
GC18425 4-hydroxy Atorvastatin lactone
P-羟基阿伐他汀内酯
A metabolite of atorvastatin
GC18411 Prostaglandin B2
前列腺素B2,PGB2
A weak TP receptor agonist
GC18353 Prostaglandin A2
前列腺素A2,Medullin
A naturally occurring prostaglandin with antiviral/antitumor activity
GC18332 Oxyphenonium (bromide)
奥芬溴铵
A muscarinic acetylcholine receptor antagonist
GC18323 Picotamide
吡考胺
Picotamide是一种血小板聚集抑制剂，IC₅₀值为0.76µM。
GC18313 BAR501 Impurity A GP-BAR1 agonist
GC18310 Prostaglandin A1
前列腺素A1,PGA1
A PGE₁ dehydration product with anti-tumor and vasodilatory activity
GC18260 FTase Inhibitor I
N-[(2S)-((2R)-2-氨基-3-巯基丙基氨基)-3-甲基丁基]-L-苯丙氨酰-L-蛋氨酸,B581
A potent and selective FTase inhibitor
GC18241 Lysophosphatidylcholines
L-溶血卵磷脂,Lyso-Lecithins (egg)
Lysophosphatidylcholines是一类重要的磷脂分子，是磷脂酶A2水解磷脂酰胆碱的产物。
GC18235 1-O-Hexadecyl-sn-glycerol
鲛肝醇,α-Chimyl Alcohol, (S)-(+)-Chimyl Alcohol
An alkyl glyceryl ether
GC18231 Urocortin II (human) (trifluoroacetate salt) A neuropeptide hormone
GC18219 6-hydroxy Warfarin
3-(Α-丙酮基苄基)-4,6-二羟基香豆素
A phase I metabolite of (+)-warfarin
GC18202 Temocaprilat
替莫普利
An ACE inhibitor
GC17816 I-BOP Potent agonist of TP receptor-mediated platelet aggregation and vascular smooth muscle contraction
GC16536 Phenyl sulfate
GC17258 β-Estradiol-d3
bata-雌二醇,β-Estradiol-d3; 17β-Estradiol-d3; 17β-Oestradiol-d3
β-Estradiol-d3是内源性雌激素17β-Estradiol的氘代标记化合物。
GC10929 Mastoparan X
G protein activator peptide
GC10971 Mexiletine HCl
盐酸美西律
A sodium channel blocker and class Ib antiarrhythmic agent
GP10027 heparin cofactor II precursor fragment [Homo sapiens]
H2N-Tyr-Glu-Ile-Thr-Thr-Ile-His-Asn-Leu-Phe-Arg-OH

Thrombin inhibitor
GP10040 heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]
H2N-Phe-Thr-Val-Asp-Arg-Pro-Phe-Leu-Phe-Leu-Ile-Tyr-Glu-His-Arg-OH

Thrombin inhibitor
GP10011 Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell
Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys-OH
一氧化氮生产阻滞剂
GP10062 Endothelin-1 (1-15), amide, human
H2N-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-NH2

Vasoconstrictor agent
GP10117 Endostatin (84-114)-NH2 (JKC367)
H2N-Pro-Gly-Ala-Arg-Ile-Phe-Ser-Phe-Asp-Gly-Lys-Asp-Val-Leu-Arg-His-Pro-Thr-Trp-Pro-Gln-Lys-Ser-Val-Trp-His-Gly-Ser-Asp-Pro-Asn-NH2
血管生成抑制剂
GP10071 BNP (1-32), human
醋酸奈西立肽,H2N-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu-Arg-Arg-His-OH
BNP (1-32), human是一种具有生物活性的32个氨基酸的多肽，包含一个17个氨基酸的二硫环和线性的76个氨基酸N端肽（NT），具有心肾保护特性。
GP10072 Pro-Adrenomedullin (153-185), human
H2N-Ser-Leu-Pro-Glu-Ala-Gly-Pro-Gly-Arg-Thr-Leu-Val-Ser-Ser-Lys-Pro-Gln-Ala-His-Gly-Ala-Pro-Ala-Pro-Pro-Ser-Gly-Ser-Ala-Pro-His-Phe-Leu-OH

Vasodilator
GP10053 Prothrombin (474-477) [Mus musculus]
H2N-Tyr-Ile-His-Pro-OH

Role in coagulation cascade
GP10134 coagulation factor II (thrombin) B chain fragment [Homo sapiens]
H2N-Lys-Pro-Val-Ala-Phe-Ser-Asp-Tyr-Ile-His-Pro-Val-Cys-Leu-Pro-Asp-Arg-OH

Trypsin-like serine protease
GP10120 Angiotensin 1/2 + A (2 - 8)
H2N-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
Vasoconstrictor
GP10012 Angiotensin 1/2 (1-8) amide
H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide

Vasoconstrictor
GP10144 Angiotensin 1/2 (1-7) amide
H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide

Vasoconstrictor
GP10099 amyloid A protein fragment [Homo sapiens]
H2N-Ala-Gly-Leu-Pro-Glu-Lys-Tyr-OH
Apolipoproteins related to HDL in plasma
GP10045 Angiotensin 1/2 (2-7)
H2N-Arg-Val-Tyr-Ile-His-Pro-OH

Vasoconstrictor
GP10079 Angiotensin 1/2 (5-7)
H2N-Ile-His-Pro-OH

Vasoconstrictor
GP10067 Angiotensin 1/2 (1-6)
H2N-Asp-Arg-Val-Tyr-Ile-His-OH

血管紧张素 I/II 1-6 含有氨基酸 1-6，由血管紧张素 I/II 肽转化而来。
GP10074 Angiotensin 1/2 (1-5)
H2N-Asp-Arg-Val-Tyr-Ile-OH

血管紧张素 I/II 1-5 是一种含有氨基酸 1-5 的肽，由血管紧张素 I/II 转化而来。
GP10085 Thrombin Receptor Activator for Peptide 5 (TRAP-5)
H2N-Ser-Phe-Leu-Leu-Arg-OH

凝血酶受体激活剂 5 (TRAP-5) 也称为凝血因子 II 受体 (1-5) 或蛋白酶激活受体 1 (1-5)，用于研究冠心病 (CHD)。
GP10059 Acetyl Angiotensinogen (1-14), porcine
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH

Angiotensinogen precursor
GP10127 Cadherin Peptide, avian
H2N-Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-amide

Role in cell adhesion
GP10115 GTP-Binding Protein Fragment, G alpha
H2N-Cys-Gly-Ala-Gly-Glu-Ser-Gly-Lys-Ser-Thr-Ile-Val-Lys-Gln-Met-Lys-OH

Hydrolyzes GTP to GDP
GP10089 Platelet Membrane Glycoprotein IIB Peptide (296-306)
H2N-Thr-Asp-Val-Asn-Gly-Asp-Gly-Arg-His-Asp-Leu-OH

Inhibits platelet aggregation
GP10121 Ac-Endothelin-1 (16-21), human
Ac-His-Leu-Asp-Ile-Ile-Trp-OH

ETA/ETB agonist,vasoconstrictor
GP10137 ANP (1-11), rat
H2N-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH

Vasodilator
GP10025 Angiotensin 1/2 (1-9)
血管紧张素I,H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-OH

血管收缩药
GP10113 Adrenomedullin (1-12), human
H2N-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-OH

An N-terminal fragment of adrenomedullin