Integrin(整合素)

Intergrin is a cell adhesion receptor for extracellular matrix protein binding. It is also involved in cell to cell interaction and triggers a variety of signaling pathways for cell proliferation, survival and mobility etc.

Products for Integrin

Cat.No. 产品名称 Information
GC10048 MNS
3,4-亚甲二氧-beta-硝基苯乙烯,NSC 170724; 5-(2-Nitrovinyl)benzodioxole
An inhibitor of Src, Syk, and platelet aggregation
GC13559 Cilengitide
西仑吉肽; EMD 121974
Cilengitide是一种环化五肽，是一种强效整合素拮抗剂，对ανβ3、ανβ5和α5β1的IC₅₀值分别为0.61nM、8.4nM和14.9nM。
GC11371 Tirofiban hydrochloride monohydrate
盐酸替罗非班水合物; L700462 hydrochloride monohydrate; MK383 hydrochloride monohydrate
A GPIIb/IIIa antagonist
GC14804 Firategrast
非拉司特; SB 683699
Firategrast (SB 683699) 是一种具有口服活性的特异性 α4β1/α4β7 整合素拮抗剂。
GN10535 Cucurbitacin B
葫芦素 B

A natural triterpene
GC17610 Cyclo (-RGDfK)
Cyclo(-Arg-Gly-Asp-D-Phe-Lys)
Cyclo (-RGDfK) 是一种高效且特异性较高的 αvβ3 整合素抑制剂，其半抑制浓度（IC₅₀）仅为 0.94nM，能够精准靶向肿瘤细胞表面的 αvβ3 整合素。